Rchr
J-GLOBAL ID：201101080759095162
Update date: Aug. 02, 2024
SASSA Takayuki
サッサ タカユキ | SASSA Takayuki
Affiliation and department：
Job title：
Associate Professor
Research field (2)：
Pharmaceuticals - health and biochemistry
, Neuroscience - general
Research keywords (6)：
Very-long-chain fatty acids
, ELOVL fatty acid elongases
, Sphingolipids
, Skin barrier
, Oral barrier
, Tear film lipids
Research theme for competitive and other funds (5)：
- 2022 - 2026 生体バリアを形成する極長鎖脂質の多様性と機能の解明
- 2019 - 2022 消化管バリアにおける極長鎖脂質の分布と機能の解明
- 2016 - 2019 Study of very long-chain fatty acids using genetically modified mice.
- 2012 - 2015 Fatty acid elongase ELOVL1: function and diseases
- 2002 - 2003 ゼブラフィッシュ小脳プルキンエ細胞活動観察系の確立
Papers (42)：
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Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. eLife. 2024. 12
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Yuta Yamamoto, Takayuki Sassa, Akio Kihara. Comparison of skin barrier abnormalities and epidermal ceramide profiles among three ω-O-acylceramide synthesis-deficient mouse strains. Journal of dermatological science. 2024. 113. 1. 10-17
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Takayuki Sassa, Akio Kihara. Involvement of ω-O-acylceramides and protein-bound ceramides in oral permeability barrier formation. Cell reports. 2023. 42. 4. 112363
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Yuka Tamura, Takayuki Sassa, Takumi Nishizawa, Akio Kihara. Incomplete Elongation of Ultra-long-chain Polyunsaturated Acyl-CoAs by the Fatty Acid Elongase ELOVL4 in Spinocerebellar Ataxia Type 34. Molecular and cellular biology. 2023. 43. 2. 1-17
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Ayami Arai, Takuya Takeichi, Hiroyuki Wakamoto, Takayuki Sassa, Yasutoshi Ito, Yuya Murase, Tomoo Ogi, Masashi Akiyama, Akio Kihara. Ceramide profiling of stratum corneum in Sjögren-Larsson syndrome. Journal of dermatological science. 2022. 107. 3. 114-122
ｍore...
Education (2)：
- - 2001 Kyoto University Graduate School of Science
- - 1995 Kyoto University Faculty of Science
Professional career (1)：
Work history (4)：
- 2015 - 現在 Hokkaido University Faculty of Pharmaceutical Sciences
- 2009 - 2015 Hokkaido University Faculty of Pharmaceutical Sciences
- 2006 - 2009 University of North Carolina at Chapel Hill, Neuroscience Center
- 2001 - 2006 RIKEN Brain Science Institute
Association Membership(s) (5)：
Japanese Society for Ceramides
, THE JAPAN NEUROSCIENCE SOCIETY
, THE JAPANESE BIOCHEMICAL SOCIETY
, 日本脂質生化学会
, 日本神経化学会
