Rchr
J-GLOBAL ID:201101081256089684
Update date: Apr. 15, 2024
Umemura Mariko
Umemura Mariko
Affiliation and department:
Tokyo University of Pharmacy and Life Sciences School of Life Science
About Tokyo University of Pharmacy and Life Sciences School of Life Science
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Detailed information
Research field (3):
Molecular biology
, Neuroscience - general
, Applied biochemistry
Research keywords (5):
脳神経疾患
, マウス
, 脳・神経
, 転写因子
, ストレス応答
Research theme for competitive and other funds (4):
2021 - 2024 大脳皮質の構築が異常の原因となる自閉症発症の分子機構の解明
2017 - 2020 Functional analysis of the mechanism of hyperactivity disorder caused by dopaminergic abnormality and psychological stress
2011 - 2013 Starvation stress-responsive transcription factor is involved in the regulation of memory-independent social behavior of mouse
2009 - 2010 Functional analysis of stress-response protein in the mouse brain
Papers (26):
Chiharu Ishii, Haruo Nakano, Riko Higashiseto, Yusaku Ooki, Mariko Umemura, Shigeru Takahashi, Yuji Takahashi. Nescient helix-loop-helix 1 (Nhlh1) is a novel activating transcription factor 5 (ATF5) target gene in olfactory and vomeronasal sensory neurons in mice. Cell and tissue research. 2024. 396. 1. 85-94
Haruo Nakano, Ayano Hata, Usato Ishimura, Ryo Kosugi, Eina Miyamoto, Kota Nakamura, Takumi Muramatsu, Moe Ogasawara, Motohiro Yamada, Mariko Umemura, et al. Activating transcription factor 5 (ATF5) controls intestinal tuft and goblet cell expansion upon succinate-induced type 2 immune responses in mice. Cell and tissue research. 2023. 393. 2. 343-355
Yoko Itakura, Yasuko Hasegawa, Yurika Kikkawa, Yuina Murakami, Kosuke Sugiura, Chiaki Nagai-Okatani, Norihiko Sasaki, Mariko Umemura, Yuji Takahashi, Tohru Kimura, et al. Spatiotemporal changes of tissue glycans depending on localization in cardiac aging. Regenerative therapy. 2023. 22. 68-78
Takehiko Yoko-O, Akiko Komatsuzaki, Erina Yoshihara, Song Zhao, Mariko Umemura, Xiao-Dong Gao, Yasunori Chiba. Regulation of alcohol oxidase gene expression in methylotrophic yeast Ogataea minuta. Journal of bioscience and bioengineering. 2021. 132. 5. 437-444
Haruo Nakano, Shiori Kawai, Yusaku Ooki, Tomoki Chiba, Chiharu Ishii, Takumi Nozawa, Hisako Utsuki, Mariko Umemura, Shigeru Takahashi, Yuji Takahashi. Functional validation of epitope-tagged ATF5 knock-in mice generated by improved genome editing of oviductal nucleic acid delivery (i-GONAD). Cell and tissue research. 2021. 385. 1. 239-249
more...
MISC (3):
高橋勇二, 梅村真理子, 時下進一, 関洋一, 佐藤健吾. 産学公連課題解決型授業の学修効果. 東京薬科大学研究紀要. 2018. 21. 7-12
Haruo Nakano, Yoshitaka Iida, Marie Aoki, Makoto Suzuki, Miyu Yamamoto, Takahiro Murase, Mariko Umemura, Shigeru Takahashi, Yuji Takahashi. Transcription factor ATF5 controls the maturation and survival of mouse vomeronasal sensory neurons. CHEMICAL SENSES. 2016. 41. 9. E152-E152
Mariko Umemura, Yoshifumi Jigami. Lipid remodelling pathway of glycosylphosphatidylinositol (GPI) -anchored proteins. Pharma VISION NEWS. 2007. 10. 23-26
Patents (5):
セラミドの付加したGPIアンカー型タンパク質の製造方法
GPIアンカー型タンパク質の脂質リモデリングに関与する遺伝子、タンパク質、およびその利用法。
GPIアンカー型タンパク質の脂質リモデリングに関与する遺伝子、タンパク質、およびその利用法。
GWT1遺伝子産物の酵素活性を阻害する化合物をスクリーニングする方法
GWT1遺伝子産物の酵素活性を阻害する化合物をスクリーニングする方法
Education (1):
2006 - 2008 University of Tsukuba Graduate School of Life and Environmental Sciences
Professional career (1):
博士(農学)
Work history (3):
2018/04 - 現在 Tokyo University of Pharmacy and Life Sciences School of Life Sciences Lecturer
2008/06 - 2018/03 Tokyo University of Pharmacy and Life Sciences School of Life Sciences Assistant Professor
- 2008/06 National Institute of Advanced Industrial Science and Technology (AIST) Research Center for Medical Glycoscience
Awards (1):
2008/03 - 筑波大学大学院 生命環境科学研究科長賞
Association Membership(s) (2):
THE JAPAN NEUROSCIENCE SOCIETY
, THE JAPANESE BIOCHEMICAL SOCIETY
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