Nozumi Motohiro

ノズミモトヒロ | Nozumi Motohiro

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.med.niigata-u.ac.jp/bc2/index.html

Research field (2)： Cell biology , Neuroscience - general

Research keywords (12)： 3D-STED , 3D-SIM , Super-resolution microscopy , Membrane trafficking , Cell motility , Growth cone , Cytoskeleton , Organelles , Endocytosis , Actin , Axon guidance , 包括脳ネットワーク

Research theme for competitive and other funds (12)：

2021 - 2024 極長鎖脂肪酸産生による神経軸索成長の制御機構の解明
2021 - 2023 Development of a novel method for live cell imaging of intracellular and extracellular structures in brain tissue
2021 - 2022 神経組織における細胞内構造の網羅的可視化技術の開発
2020 - 2021 網羅的オルガネラ動態の可視化による神経成長機構の解明
2018 - 2021 Actin-dependent endocytosis producing the driving force for neuronal growth

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Papers (19)：

Atsuko Honda, Motohiro Nozumi, Yasuyuki Ito, Rie Natsume, Asami Kawasaki, Fubito Nakatsu, Manabu Abe, Haruki Uchino, Natsuki Matsushita, Kazutaka Ikeda, et al. Very-long-chain fatty acids are crucial to neuronal polarity by providing sphingolipids to lipid rafts. Cell reports. 2023. 113195-113195
Masayasu Okada, Yosuke Kawagoe, Toshiyuki Takasugi, Motohiro Nozumi, Yasuyuki Ito, Hayato Fukusumi, Yonehiro Kanemura, Yukihiko Fujii, Michihiro Igarashi. JNK1-Dependent Phosphorylation of GAP-43 Serine 142 is a Novel Molecular Marker for Axonal Growth. Neurochemical research. 2022. 47. 9. 2668-2682
Masayasu Okada, Yosuke Kawagoe, Toshiyuki Takasugi, Motohiro Nozumi, Yasuyuki Ito, Hayato Fukusumi, Yonehiro Kanemura, Yukihiko Fujii, Michihiro Igarashi. Correction to: JNK1-Dependent Phosphorylation of GAP-43 Serine 142 is a Novel Molecular Marker for Axonal Growth. Neurochemical research. 2022. 47. 9. 2683-2683
Masayasu Okada, Yosuke Kawagoe, Yuta Sato, Motohiro Nozumi, Yuya Ishikawa, Atsushi Tamada, Hiroyuki Yamazaki, Yuko Sekino, Yonehiro Kanemura, Yohei Shinmyo, et al. Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates. Molecular brain. 2021. 14. 1. 66-66
Xubin Hou, Motohiro Nozumi, Harukazu Nakamura, Michihiro Igarashi, Sayaka Sugiyama. Coactosin Promotes F-Actin Protrusion in Growth Cones Under Cofilin-Related Signaling Pathway. Frontiers in cell and developmental biology. 2021. 9. 660349-660349

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MISC (14)：

河嵜麻実, 小林大記, 岡田正康, 野住素広, 武内恒成, 五十嵐道弘. リン酸化プロテオミクスで同定された、神経成長関連分子群の責任キナーゼの解析. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [4T17L-12(3P0403)]
M. Nozumi, M. Igarashi. Membrane retrieval coincides with the filopodia formation in the neuronal growth cone. MOLECULAR BIOLOGY OF THE CELL. 2014. 25
A. Kawasaki, M. Nozumi, K. Takeuchi, N. Yoshioka, M. Igarashi. The in vivo GAP-43 phosphorylation sites involved in axon growth or regeneration. JOURNAL OF NEUROCHEMISTRY. 2012. 123. 56-56
Motohiro Nozumi, Jia Lu, Kosei Takeuchi, Michihiro Igarashi. Functions of newly identified nerve growth-associated proteins in the growth cone. NEUROSCIENCE RESEARCH. 2009. 65. S97-S97
Jia Lu, Motohiro Nozumi, Haruki Abe, Michihiro Igarashi. RNAi-mediated knockdown of FABP-7 inhibits neurite outgrowth in developing cortical neurons. NEUROSCIENCE RESEARCH. 2008. 61. S233-S233

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Patents (1)：

GAP43の免疫学的分析方法及び当該方法を実行するためのキット、並びに成長円錐を検出するための試薬及び方法

Lectures and oral presentations (8)：

Visualization of various organelle dynamics by super-resolution shadow imaging of intracellular space.
(Neuro2022 2022)
Actin reorganization and plasma membrane trafficking in three-dimensional space of nerve growth cones.
(2021)
Super-resolution shadow imaging of intracellular space reveals various organelle dynamics in living cells.
(2020)
構造化照明による超解像顕微鏡(SIM)で明らかになった神経突起先端の3次元構造
(第 41 回日本分子生物学会年会ワークショップ 2018)
New relationships between F actin organization and membrane trafficking in the growth cone revealed by SIM.
(2018)

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Education (2)：

1998 - 2003 九州工業大学大学院情報工学研究科情報科学専攻
1996 - 1998 九州工業大学情報工学部生物科学システム工学科

Professional career (1)：

Ph.D. (Kyushu Institute of Technology)

Work history (6)：

2011/06 - 現在 Niigata University Department of Neurochemistry Lecturer
2021/01 - 2021/06 Universite de Bordeaux Institute for Interdisciplinary Neuroscience Visiting researcher
2019/07 - 2019/12 Universite de Bordeaux Institute for Interdisciplinary Neuroscience Visiting researcher
2008/04 - 2011/05 Niigata University Department of Neurochemistry Assistant Professor
2005/04 - 2008/03 Niigata University Department of Neurochemistry PostDoc Position

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Association Membership(s) (6)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , American Society for Cell Biology , Society for Neuroscience , THE JAPANESE BIOCHEMICAL SOCIETY , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE JAPAN NEUROSCIENCE SOCIETY

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