Rchr
J-GLOBAL ID：201101082570695641   Update date: May. 28, 2024

Ohata Shinya

オオハタ シンヤ | Ohata Shinya
Affiliation and department：
Musashino University

About Musashino University


Job title： Associate Professor
Homepage URL  (1)： https://www.musashino-u.ac.jp/research/laboratory/pharmacy/lab/saibo.html
Research field  (4)： Neuroscience - general ,  Developmental biology ,  Molecular biology ,  Pharmaceuticals - health and biochemistry
Research keywords  (6)： ependymoma ,  planar cell polarity ,  cilia ,  ependymal cell ,  neural stem cell ,  differentiation
Research theme for competitive and other funds  (10)：
  • 2024 - 2025 アンメットメディカルニーズを満たす新薬創生プロジェクト
  • 2024 - 2025 生成系AIを活用したアクティブラーニング
  • 2021 - 2024 Molecular and structural basis for the development of rare brain tumors
  • 2020 - 2023 Elucidation of ependymoma pathogenesis and search for therapeutic targets
  • 2020 - 2023 Elucidation of the mechanism of ependymoma caused by abnormal ependymal cell differentiation
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Papers (25)：
  • Masaki Ishii, Tsuyoshi Yamada, Kazuki Ishikawa, Koji Ichinose, Michel Monod, Shinya Ohata. The Ptk2-Pma1 pathway enhances tolerance to terbinafine in Trichophyton rubrum. Antimicrobial agents and chemotherapy. 2024. 68. 5. e0160923
  • Masaki Ishii, Tsuyoshi Yamada, Shinya Ohata. An efficient gene targeting system using Δku80 and functional analysis of Cyp51A in Trichophyton rubrum. bioRχiv. 2024
  • Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohata. Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence. iScience,. 2024. in press
  • Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohata. TrCla4 promotes actin polymerization at the hyphal tip and mycelial growth in Trichophyton rubrum. Microbiology Spectrum. 2023. 5. e0292323
  • Kazuki Ishikawa, Masaki Ishii, Takashi Yaguchi, Toshiaki Katada, Koji Ichinose, Shinya Ohata. <i>epi</i>-Aszonalenin B from <I>Aspergillus novofumigatus</i> inhibits NF-κB activity induced by ZFTA-RELA fusion protein that drives ependymoma. Biochemical and Biophysical Research Communications. 2022. 596. 104-110
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MISC (27)：
  • Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohata. Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence. bioRχiv. 2024
  • Masaki Ishii, Tsuyoshi Yamada, Michel Monod, Shinya Ohata. The Ptk2-Pma1 pathway enhances tolerance to terbinafine in Trichophyton rubrum. bioRχiv. 2023
  • Shinya Ohata. Pathogenesis of ependymomas arising due to abnormal ependymal cell differentiation. Advances in Pharmaceutical Sciences. 2023. 39. 17-28
  • Search for anti-Rhizopus oryzae active substances from fungi of Aspergillus genus. 2022. 142年会. 27PO1-23S
  • Herranz-Pérez V, Nakatani J, Ishii M, Katada T, García-Verdugo JM, Ohata S. Ependymoma associated protein Zfta is expressed in immature ependymal cells but is not essential for ependymal development in mice. Research Square. 2021
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Lectures and oral presentations  (82)：
  • Exploration of fungal metabolites that inhibit oncogenic NF-κB signaling and elucidation of their mechanism of action
    (2024)
  • Exploration of NF-κB signalling inhibitors by fungal secondary metabolites to overcome unmet medical needs
    (2024)
  • Cryo-EM構造解析により明らかにするPPARgの核内輸送機構
    (日本薬学会第144年会 2024)
  • Analysis and Utilization of Free Descriptions in Teaching Evaluation Questionnaires - A Case Study of IR and FD Collaboration at Musashino University-
    (The 30th University Education Research Forum 2024)
  • 響学スパイラルとアクティブラーニングを活用した学修技術獲得の試み
    (第16回日本医療教授システム学会 総会・学術集会 2024)
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Professional career (1)：
  • Ph.D. (Pharmaceutical Sciences) (The University of Tokyo)
Work history (10)：
  • 2023/08 - 現在 Musashino University Center for the Development of Enhanced Learning
  • 2021/04 - 現在 Musashino University Graduate School of Pharmaceutical Sciences
  • 2017/04 - 現在 Musashino University Faculty of Pharmacy
  • 2019/07 - 2019/07 Council on Pharmaceutical Education Completed a training workshop for certified practical training pharmacists
  • 2015/07 - 2017/03 University of Tokyo
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Committee career (15)：
  • 2024/04 - 現在 武蔵野大学 学術機関リポジトリ運営委員
  • 2024/04 - 現在 武蔵野大学 図書委員
  • 2024/03 - 現在 薬学教育協議会 生化学分野教科担当教員
  • 2024/03 - 現在 Faculty of Pharmacy, Musashino University Working Group for the Improvement of Learning
  • 2023/10 - 現在 生命科学研究会 第21回生命科学研究会世話人
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Awards (9)：
  • 2023/12 - 日本細菌学会関東支部会 優秀発表賞 トポイソメラーゼI阻害は上衣腫のNF-κB活性化を抑制する
  • 2020/09 - 日本薬学会関東支部 優秀ポスター発表賞 皮膚糸状菌Rac及びCDC42の菌糸成長における機能解析
  • 2014 - MBSJ Travel Grant
  • 2014 - Cell Science Foundation Fellowship
  • 2011 - The National Science Foundation Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring
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Association Membership(s) (3)：
Japan Society for Instructional Systems in Healthcare ,  The Pharmaceutical Society of Japan ,  Japanese Society of Molecular Biology
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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