Rchr
J-GLOBAL ID：201101082570695641   Update date: Nov. 07, 2024

Ohata Shinya

オオハタ シンヤ | Ohata Shinya
Affiliation and department：
Musashino University

About Musashino University


Job title： Associate Professor
Homepage URL  (1)： https://www.musashino-u.ac.jp/research/laboratory/pharmacy/lab/saibo.html
Research field  (4)： Neuroscience - general ,  Developmental biology ,  Molecular biology ,  Pharmaceuticals - health and biochemistry
Research keywords  (6)： ependymoma ,  planar cell polarity ,  cilia ,  ependymal cell ,  neural stem cell ,  differentiation
Research theme for competitive and other funds  (10)：
  • 2024 - 2025 Drug Discovery Project to Satisfy Unmet Medical Needs
  • 2024 - 2025 Active learning using generative AI
  • 2021 - 2024 Molecular and structural basis for the development of rare brain tumors
  • 2020 - 2023 Elucidation of ependymoma pathogenesis and search for therapeutic targets
  • 2020 - 2023 Elucidation of the mechanism of ependymoma caused by abnormal ependymal cell differentiation
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Papers (27)：
  • Kazuki Ishikawa, Nao Kamiya, Masaki Ishii, Takashi Yaguchi, Koji Ichinose, Shinya Ohata. Aszonapyrone A Isolated from Neosartorya spinosa IFM 47025 Inhibits the NF-κB Signaling Pathway Activated by Expression of the Ependymoma-causing Fusion Protein ZFTA-RELA. Advances in Microbiology. 2024. 14. 9. 448-467
  • Sachiko Toma-Fukai, Yutaro Nakamura, Akihiro Kawamoto, Hikaru Shimizu, Koki Hayama, Ruri Kojima, Kanami Yoshimura, Masaki Ishii, Mika Hirose, Toshiaki Teratani, et al. Structural insight into the nuclear transportation mechanism of PPARg by Transportin-1. bioRχiv. 2024
  • Masaki Ishii, Tsuyoshi Yamada, Shinya Ohata. An efficient gene targeting system using Δku80 and functional analysis of Cyp51A in Trichophyton rubrum. AMB Express. 2024. 14. 96
  • Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohata. Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence. iScience. 2024. 27. 6. 110139
  • Masaki Ishii, Tsuyoshi Yamada, Kazuki Ishikawa, Koji Ichinose, Michel Monod, Shinya Ohata. The Ptk2-Pma1 pathway enhances tolerance to terbinafine in Trichophyton rubrum. Antimicrobial Agents and Chemotherapy. 2024. 68. 5. e0160923
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MISC (28)：
  • Masaki Ishii, Tsuyoshi Yamada, Shinya Ohata. An efficient gene targeting system using Δku80 and functional analysis of Cyp51A in Trichophyton rubrum. bioRχiv. 2024
  • Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohata. Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence. bioRχiv. 2024
  • Masaki Ishii, Tsuyoshi Yamada, Michel Monod, Shinya Ohata. The Ptk2-Pma1 pathway enhances tolerance to terbinafine in Trichophyton rubrum. bioRχiv. 2023
  • Shinya Ohata. Pathogenesis of ependymomas arising due to abnormal ependymal cell differentiation. Advances in Pharmaceutical Sciences. 2023. 39. 17-28
  • Search for anti-Rhizopus oryzae active substances from fungi of Aspergillus genus. 2022. 142年会. 27PO1-23S
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Lectures and oral presentations  (86)：
  • Molecular and Structural Bases of Nuclear transportation of ZFTA-RELA fusion protein that drives ependymoma
    (The 47th Annual Meeting of the Japanese Society for Molecular Biology 2024)
  • Nuclear migration mechanism of ependymoma-causing protein ZFTA-RELA FUS2.
    (21st Life Sciences Research Meeting 2024)
  • Structural studies to elucidate the nuclear transport mechanism of the ependymoma-causing protein ZFTA-RELA.
    (The 24th Annual Meeting of the Japanese Society for Protein Science 2024)
  • Structural studies to elucidate the nuclear transport mechanism of the ependymoma-causing protein ZFTA-RELA
    (The 70th regular meeting of the Kinki Branch of the Biochemical Society 2024)
  • Exploration of fungal metabolites that inhibit oncogenic NF-κB signaling and elucidation of their mechanism of action
    (2024)
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Professional career (1)：
  • Ph.D. (Pharmaceutical Sciences) (The University of Tokyo)
Work history (10)：
  • 2023/08 - 現在 Musashino University Center for the Development of Enhanced Learning
  • 2021/04 - 現在 Musashino University Graduate School of Pharmaceutical Sciences
  • 2017/04 - 現在 Musashino University Faculty of Pharmacy
  • 2019/07 - 2019/07 Council on Pharmaceutical Education Completed a training workshop for certified practical training pharmacists
  • 2015/07 - 2017/03 University of Tokyo
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Committee career (16)：
  • 2024/04 - 現在 Faculty of Pharmaceutical Sciences, Musashino University Comprehensive Selection Review Committee
  • 2024/04 - 現在 Musashino University Academic Institutional Repository Steering Committee
  • 2024/04 - 現在 Musashino University Librarian
  • 2024/03 - 現在 Council of Pharmaceutical Education Biochemistry Subject Faculty
  • 2024/03 - 現在 Faculty of Pharmacy, Musashino University Working Group for the Improvement of Learning
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Awards (9)：
  • 2023/12 - Kanto Branch Meeting of the Bacteriological Society of Japan Best Presentation Award Topoisomerase I inhibition inhibits NF-κB activation in ependymomas.
  • 2020/09 - Kanto Branch of the Pharmaceutical Society of Japan Best Poster Presentation Award Functional analysis of dermatophyte Rac and CDC42 in mycelial growth
  • 2014 - MBSJ Travel Grant
  • 2014 - Cell Science Foundation Fellowship
  • 2011 - The National Science Foundation Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring
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Association Membership(s) (3)：
Japan Society for Instructional Systems in Healthcare ,  The Pharmaceutical Society of Japan ,  Japanese Society of Molecular Biology
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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