Rchr
J-GLOBAL ID:201101083281524665   Update date: Aug. 23, 2024

Nakai Hiroyuki

ナカイ ヒロユキ | Nakai Hiroyuki
Affiliation and department:
Research field  (2): Food sciences ,  Applied biochemistry
Research keywords  (3): 物質生産 ,  糖質科学 ,  酵素化学
Research theme for competitive and other funds  (7):
  • 2022 - 2025 糖質の構造と生理活性の相関解明に向けた機能性糖質の創生
  • 2019 - 2022 Screening of novel carbohydrate phosphorylase using carbohydrate assimilation modified Escherichia coli
  • 2016 - 2019 Screening of novel carbohydrate phosphorylase using metagenomics
  • 2014 - 2017 Studies on the energetically efficient metabolic pathway of N-glycans in intestinal bacteria
  • 2014 - 2016 Screening of carbohydrate phosphorylases enabling practical synthesis of oligosaccharides
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Papers (81):
  • Sei Motouchi, Shiro Komba, Hiroyuki Nakai, Masahiro Nakajima. Discovery of Anomer-Inverting Transglycosylase: Cyclic Glucohexadecaose-Producing Enzyme from Xanthomonas, a Phytopathogen. Journal of the American Chemical Society. 2024. 146. 26. 17738-17746
  • Meng-Shu Hao, Scott Mazurkewich, He Li, Alma Kvammen, Srijani Saha, Salla Koskela, Annie R. Inman, Masahiro Nakajima, Nobukiyo Tanaka, Hiroyuki Nakai, et al. Structural and biochemical analysis of family 92 carbohydrate-binding modules uncovers multivalent binding to β-glucans. Nature Communications. 2024. 15. 1
  • Nobukiyo Tanaka, Ryotaro Saito, Kaito Kobayashi, Hiroyuki Nakai, Shogo Kamo, Kouji Kuramochi, Hayao Taguchi, Masahiro Nakajima, Tomoko Masaike. Functional and structural analysis of a cyclization domain in a cyclic β-1,2-glucan synthase. Applied Microbiology and Biotechnology. 2024. 108. 1
  • Sei Motouchi, Kaito Kobayashi, Hiroyuki Nakai, Masahiro Nakajima. Identification of enzymatic functions of osmo-regulated periplasmic glucan biosynthesis proteins from Escherichia coli reveals a novel glycoside hydrolase family. Communications Biology. 2023. 6. 1
  • Ami Koizumi, Ken Miyazawa, Makoto Ogata, Yuzuru Takahashi, Shigekazu Yano, Akira Yoshimi, Motoaki Sano, Masafumi Hidaka, Takanori Nihira, Hiroyuki Nakai, et al. Cleavage of α-1,4-glycosidic linkages by the glycosylphosphatidylinositol-anchored α-amylase AgtA decreases the molecular weight of cell wall α-1,3-glucan in Aspergillus oryzae. Frontiers in Fungal Biology. 2023. 3. Article 1061841
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MISC (62):
Patents (9):
  • β-マンノシドの製造方法
  • グルコシル-α-1,2-グリセロールホスホリラーゼ及びそれを用いたグルコシル-α-1,2-グリセロールの製造方法
  • セロビオン酸ホスホリラーゼおよびそれを用いた酸性βグルコシル二糖の製造法
  • オリゴ糖合成酵素並びにβ-1,2-マンノビオース及びその誘導体の製造方法
  • オリゴ糖合成酵素およびアスパラギン結合型糖タンパク質のコア糖鎖構造の製造方法
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Education (2):
  • - 2005 Hokkaido University Graduate School, Division of Agriculture
  • - 2000 Hokkaido University Faculty of Agriculture
Professional career (1):
  • 博士(農学) (北海道大学)
Work history (6):
  • 2015/04/01 - 現在 Niigata University Faculty of Agriculture Department of Applied Biological Chemistry Associate Professor
  • 2010/12 - 2015/03 Niigata University Graduate School of Science and Technology Assistant Professor
  • 2010/10 - 2010/11 National Agriculture and Food Research Organization, National Food Research Institute
  • 2008/09/15 - 2010/09/15 デンマーク工科大学 助教
  • 2007/09 - 2008/08 デンマーク工科大学 博士研究員
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Awards (13):
  • 2021/09 - 日本応用糖質科学会 ポスター賞
  • 2020/03 - 日本農芸化学会 2020年度大会トピックス賞
  • 2017/09 - 日本応用糖質科学会 奨励賞
  • 2017/03 - 日本農芸化学会 2017年度大会トピックス賞
  • 2016/04 - 公益財団法人 長瀬科学技術振興財団 長瀬研究振興賞
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Association Membership(s) (3):
THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH ,  JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  THE JAPANESE SOCIETY OF APPLIED GLYCOSCIENCE
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