Research theme for competitive and other funds (14):
2021 - 2025 胎生期における超早期脳ゲノム編集治療法の開発
2022 - 2024 Understanding of the regulation of sleep and wakefulness by CRF neurons in mice
2021 - 2024 概日時計による体温調節メカニズムの解明
2020 - 2024 Understanding of sleep-wake regulatory mechanisms in nature
2022 - 2024 厳しい地球環境に適応するための哺乳類生体機能の解明
2021 - 2023 哺乳類の昼行性・夜行性を決定する神経メカニズムの解明
2021 - 2023 時間感覚と睡眠・覚醒リズムを形成する神経基盤の解明
2021 - 2023 概日時計が制御するシンギュラリティー神経回路の探索
2018 - 2021 Understanding of neuronal circuits that are related circadian clock regulated sleep/wakefulness
2015 - 2018 Hierarchical self-organization of circadian system: synchronization of cellular oscillators and pacemaker coupling
2015 - 2018 Measurement of transcription activity in freely moving mice: Ultradian rhythms and their physiological roles
2014 - 2017 Understanding of circadian system in the central circadian clock using in vivo recording
2012 - 2014 Molecular mechanisms of the cellular coupling in the SCN during postnatal development
2009 - 2011 哺乳類概日リズム形成機構の解明 : in vitro, in vivo単一細胞イメージング
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Papers (44):
Hiroto Ito, Noriaki Fukatsu, Sheikh Mizanur Rahaman, Yasutaka Mukai, Shuntaro Izawa, Daisuke Ono, Thomas S. Kilduff, Akihiro Yamanaka. Deficiency of orexin signaling during sleep is involved in abnormal REM sleep architecture in narcolepsy. Proceedings of the National Academy of Sciences. 2023. 120. 41
Yasutaka Mukai, Tatsuo S. Okubo, Michael Lazarus, Daisuke Ono, Kenji F. Tanaka, Akihiro Yamanaka. Prostaglandin E2Induces Long-Lasting Inhibition of Noradrenergic Neurons in the Locus Coeruleus and Moderates the Behavioral Response to Stressors. The Journal of Neuroscience. 2023. 43. 47. 7982-7999
Apirada Padlom, Daisuke Ono, Rio Hamashima, Yuko Furukawa, Takashi Yoshimura, Taeko Nishiwaki-Ohkawa. Level of constitutively expressed BMAL1 affects the robustness of circadian oscillations. Scientific reports. 2022. 12. 1. 19519-19519
Daisuke Ono. Neural circuits in the central circadian clock and their regulation of sleep and wakefulness in mammals. Neuroscience research. 2022. 182. 1-6
Circadian clock and postnatal development. 2016. 67. 6. 550-554
Honma S, Ono D, Enoki R, Yoshikawa T, Kuroda S, Honma K. Oscillator networks in the suprachiasmatic nucleus: analysis of circadian parameters using time-laps images. Biological Clocks - 30th Anniversary of Sapporo Symposium on Biological Rhythm, (eds by Honma K and Honma S). 2016. 33-41
Shin-ya Nishide, Yoko Suzuki, Daisuke Ono, Ken-ichi Honma, Sato Honma, Serge Daan. Hypothermia is induced by restricted feeding in mice : Effect of time of day. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S259-S259
Ryosuke Enoki, Shigeru Kuroda, Daisuke Ono, Hasan Mazahir, Tetsuo Ueda, Sato Honma, Ken-ichi Honma. Large-Scale Circadian Calcium Imaging in Neuronal Network of the Suprachiasmatic Nucleus. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S53-S53
MURAKAMI Akitoshi, HIROTA Sinya, TAKEUCHI Akimasa, INOUE Kousuke, ONO Daisuke, HONMA Sato, KOTANI Kiyoshi, JIMBO Yasuhiko. Functional characterization of suprachiasmatic nucleus cultured with retina. 2012. 2012. 34. 21-24