Hirano Tatsuya

Affiliation and department：
Homepage URL (2)： http://www.riken.jp/chromdyna/ , http://www.riken.jp/chromdyna/index_en.html

Research field (2)： Molecular biology , Cell biology

Research keywords (8)： Xenopus laevis , Meiosis , Mitosis , SMC proteins , Cohesin , Condensin , Cell cycle , Chromosomes

Research theme for competitive and other funds (9)：

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Papers (109)：

Keishi Shintomi, Yuki Masahara-Negishi, Masami Shima, Shoji Tane, Tatsuya Hirano. Recombinant cyclin B-Cdk1-Suc1 capable of multi-site mitotic phosphorylation in vitro. PLoS One. 2024. 19. 3. e0299003
Makoto M. Yoshida, Kazuhisa Kinoshita, Keishi Shintomi, Yuuki Aizawa, Tatsuya Hirano. Regulation of condensin II by self-suppression and release mechanisms. Molecular Biology of the Cell. 2024. 35. 2. ar21
Tetsuya Yamamoto, Kazuhisa Kinoshita, Tatsuya Hirano. Elasticity control of entangled chromosomes: crosstalk between condensin complexes and nucleosomes. Biophysical journal. 2023. 122. 19. P3869-3881
Mingxuan Sun, Hossein Amiri, Alexander B Tong, Keishi Shintomi, Tatsuya Hirano, Carlos Bustamante, Rebecca Heald. Monitoring the compaction of single DNA molecules in Xenopus egg extract in real time. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 12. e2221309120
Shoji Tane, Keishi Shintomi, Kazuhisa Kinoshita, Yuko Tsubota, Makoto M Yoshida, Tomoko Nishiyama, Tatsuya Hirano. Cell cycle-specific loading of condensin I is regulated by the N-terminal tail of its kleisin subunit. eLife. 2022. 11. e84694

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MISC (28)：

平野達也. 分裂期染色体のつくり方. 月刊「細胞」. 2022
平野達也, 胡桃坂仁志. 変貌する染色体研究の最前線. 実験医学増刊号. 2018. 36. 17. 10-17
新冨圭史, 平野達也. 分裂期染色体をつくるためにヌクレオソームは本当に必須なのか?. ライフサイエンス新着論文レビュー. 2017
平野達也, インタビュー. わずか6種のタンパク質で染色体凝縮を再現. Nature ダイジェスト. 2015. 12. 12. 28-29
Mechanisms of Mitotic Chromosome Assembly Unveiled by In-Vitro Studies. 2015. 34. 11. 1034-1039

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Books (5)：

Lectures and oral presentations (197)：

Toward a deep understanding of mitotic chromosome assembly
(International Symposium on "The 3D Genome", Kobe, Japan. 2024)
Toward a deep understanding of mitotic chromosome assembly
(The 5th International SMC Meeting (NIG & RIKEN International Symposium 2024) "SMC complexes: orchestrating diverse genome functions", Numazu, Shizuoka, Japan. 2024)
A tale of two condensins: molecular dissection of mitotic genome folding machines
(RIKEN International Symposium on “Nuclear Structure and Function”, Wako, Japan. 2024)
Condensins and mitotic genome folding
(Research Lecture at Nobel Forum, Karolinska Institutet, Stockholm, Sweden. 2024)
Mitotic chromosome assembly: what happens when DNAs remain entangled?
(BIE International Symposium, Wako, Japan. 2024)

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Professional career (1)：

Work history (16)：

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Awards (7)：

2019 - The Asahi Prize
2017 - The commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology (Research Category)
2005 - The American Association for the Advancement of Science (AAAS) Fellow
2003 - ISI Highly Cited Researcher
1996 - Pew Scholarship

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Association Membership(s) (2)：

Member, The American Society for Cell Biology , Member, The Molecular Biology Society of Japan

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