NOMURA Jun

ノムラジュン | NOMURA Jun

Affiliation and department：
Job title： Lecturer
Homepage URL (2)： https://nrid.nii.ac.jp/en/nrid/1000070406528/ , http://www.researchgate.net/profile/Jun_Nomura/

Research field (6)： Neuroscience - general , Pharmaceuticals - health and biochemistry , Animals: biochemistry, physiology, behavioral science , Molecular biology , Psychiatry , Pathobiochemistry

Research keywords (11)： Schizophrenia , Mental Disorders , Developmental Disorders , Autism , Chromosome Engineering , Genome editing , Stem Cells , Knockout mouse , Gene Targeting , Differentiation , Oncogenicity

Research theme for competitive and other funds (13)：

2024 - 2027 Phase-specific risk factor analysis of the translation process in autism
2021 - 2024 Identifying drug targets for neuropsychiatric and neurodevelopmental disorders via brain transcriptome
2018 - 2023 Integrated analysis of the human chromosome 15q13.3 copy number variation
2017 - 2020 Develop and analysis for chromosome mutant mice
2016 - 2017 RIKEN-MITI FS research fund

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Papers (26)：

Sawako Furukawa*, Jun Nomura* (contributed equally), HIroaki Hanafusa, Hiroko Maegawa, Toru Takumi. Germ-cell-specific transcriptome analysis illuminates the chromatin and ubiquitin pathway in autism spectrum disorders. Autism Research. 2023. 16. 6. 1101-1110
Chia-Wen Lin, Dian E. Septyaningtrias, Hsu-Wen Chao, Mikiko Konda, Koji Atarashi, Kozue Takeshita, Kota Tamada, Jun Nomura, Yohei Sasagawa, Kaori Tanaka, et al. A common epigenetic mechanism across different cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model. Molecular Psychiatry. 2022. 27. 8. 3343-3354
Jun Nomura, Amila Zuko, Keiko Kishimoto, Hiroaki Mutsumine, Kazumi Fukatsu, Yoshiko Nomura, Xiaoxi Liu, Nobuhiro Nakai, Eiki Takahashi, Tsukasa Kouno, et al. Autism in a dish: ES cell models of autism with copy number variations reveal cell-type-specific vulnerability. BioRxiv. 2022
Yoshiko Nomura, Jun Nomura, Toru Nishikawa, Toru Takumi. Reciprocal differentiation via GABAergic components and ASD-related phenotypes in hES with 1q21.1 CNV. BioRrxiv. 2021
Jun Nomura, Matthew Mardo, Toru Takumi. Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia. Journal of Neurochemistry. 2021. 159. 4. 647-659

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MISC (14)：

Nomura J, Takumi T. Identification of cell type-specific autism risk factors by single-cell, organoid studies. Japanese Journal of Biological Psychiatry. 2022. 33. 2. 48-52
Jun Nomura, Toru Takumi. Emerging technologies for autism spectrum disorders. Japanese Journal of Biological Psychiatry. 2020. 31. 2. 71-75
Jun Nomura, Toru Takumi. Comprehensive analysis of the human chromosome 15q13.3 copy number variation. Smoking Research Foundation annual research report. 2019. 1132-1135
Jun Nomura, Toru Takumi. Trends in in vitro basic research for autism phenotyping. Journal of clinical and experimental medicine. 2019. 268. 3. 184-190
Jun Nomura, Akifumi Kanda, Yusuke Sotomaru, Toru Takumi. Phenotypic analysis of a mouse model for 15q25.2-25.3 deletion syndrome. International Journal of Neuropsychopharmacology. 2016. 19. Suppl_1. 3-3

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Lectures and oral presentations (31)：

【Symposium】Single-cell analysis identifies cell-type-specific molecular pathology in autism spectrum disorder
(NEURO2024 (The 47th Annual Meeting of the Japan Neuroscience Society (JNS), The 67th Annual Meeting of the Japanese Society for Neurochemistry (JSN), The 46th Annual Meeting of the Japanese society of Biological Psychiatry (JSBP), The 8th FAONS Congress) 2024)
【Oral Session】Single-cell analysis identified cell-type-specific and converged pathways of autism spectrum disorder
(The 35th WORLD CONGRESS -World Congress Collegium Internationale Neuro-Psychopharmacologicum-, The International College of Neuropsychopharmacology (CINP) 2024)
[Co-sponsored Academic Seminar 7] To 3D Cell Culture -Introduction and implementation
(The 23rd Congress of the Japanese Society for Regenerative Medicine 2024)
【Symposium】 Challenges of Organoid Research -Basics and Trends in Organoid Research-
(The 4th CMX Emergence Conference, Center for Medical Transformation Kobe University 2024)
【Symposium】Phenotypic analysis of mice with altered chromosomal regions correlated with neurodevelopmental disorders
(Japan Science and Technology Agency, Moonshot-type R&D Project Objective 9: The 2nd Mouse Society 2023)

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Education (3)：

2002 - 2005 Hokkaido University Graduate School of Pharmaceutical Sciences
1999 - 2001 Ritsumeikan University Graduate School of Science & Engineering
1995 - 1999 Ritsumeikan University Science & Engineering Environmental Systems Engineering

Professional career (1)：

Ph.D. (Pharmaceutical Sciences)

Work history (7)：

2024/04 - 現在 Kobe University School of Medicine Lecturer
2020/10 - 現在 Kobe University School of Medicine Assistant Professor
2020/04 - 2020/09 Kobe University School of Medicine Specially Appointed Assistant Professor
2016/04 - 2020/03 RIKEN Center for Brain Science Research Scientist
2011 - 2016 Hiroshima University Graduate School of Biomedical Sciences Specially Appointed Assistant Professor

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Committee career (2)：

2018 - 現在 The International College of Neuropsychopharmacology (CINP) Fellow
2016 - 現在 The Japanese Society of Neuropsychopharmacology Councilor

Awards (6)：

2023 - Journal of Neurochemistry (Wiley) Top Downloaded Article in Journal of Neurochemistry Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia
2022 - Neuroscience Research (Elsevier) Excellent Paper Award Transcriptome analysis of human neural cells derived from isogenic embryonic stem cells with 16p11.2 deletion.
2020/01 - Takeda Science Foundation, The 10th Takeda Science Foundation International Symposium on PharmaSciences Excellent Poster Award
2014 - RIKEN BSI Riken BSI Hot Topics 2014 Genome Editing Tools for Neurobiology
2009 - International Congress on Schizophrenia Research (ICOSR), Young Investigator Program Award 2009, USA, A new cell model to study the mechanism of gene-environment interactions relevant to schizophrenia

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Association Membership(s) (9)：

The Japanese Society for Bioinformatics , The Japanese Biochemical Society , The Molecular Biology Society of Japan , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE JAPAN NEUROSCIENCE SOCIETY , THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY , International College of Neuropsychopharmacology , Society for Neuroscience , The International Behavioral Neuroscience Society (IBNS)

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