Rchr
J-GLOBAL ID：201201011040301947
Update date: Dec. 06, 2024
Ohtsuka Hokuto
Ohtsuka Hokuto
Homepage URL (1)：
http://www.ps.nagoya-u.ac.jp/lab_pages/microbio/aiba/index.html
Research field (1)：
Applied microbiology
Research theme for competitive and other funds (4)：
- 2021 - 2024 Analysis of cell miniaturization under sulfur depletion-Relationship between cyclin degradation and autophagy-
- 2019 - 2022 Hidden response to amino acid depletion -Ecl1 family gene-dependent extension of lifespan-
- 2016 - 2020 Analysis of mechanism of chronological lifespan extension by sulfur depletion in fission yeast
- 2014 - 2017 Analysis of Ecl1 family proteins that extends chronological lifespan
Papers (45)：
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Hokuto Ohtsuka, Kotaro Ohara, Takafumi Shimasaki, Yoshiko Hatta, Yasukichi Maekawa, Hirofumi Aiba. A novel transcription factor Sdr1 involving sulfur depletion response in fission yeast. Genes to Cells. 2024
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Ohtsuka, H, Shimasaki, T, Aiba, H. Low-Molecular Weight Compounds that Extend the Chronological Lifespan of Yeasts, Saccharomyces cerevisiae, and Schizosaccharomyces pombe. ADVANCED BIOLOGY. 2024. 8. 5. e2400138
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Yoshiaki Kamada, Chiharu Umeda, Yukio Mukai, Hokuto Ohtsuka, Yoko Otsubo, Akira Yamashita, Takahiro Kosugi. Structure-based engineering of Tor complexes reveals that two types of yeast TORC1 produce distinct phenotypes. Journal of Cell Science. 2024. 137. 4
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Ohtsuka, H., Kawai, S., Ito, Y., Kato, Y., Shimasaki, T., Imada, K., Otsubo, Y., Yamashita, A., Mishiro-Sato, E., Kuwata, K., et al. Novel TORC1 inhibitor Ecl1 is regulated by phosphorylation in fission yeast. Aging Cell. 2024
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Maekawa, Y, Matsui, K, Okamoto, K, Shimasaki, T, Ohtsuka, H, Tani, M, Ihara, K, Aiba, H. Identification of plb1 mutation that extends longevity via activating Sty1 MAPK in Schizosaccharomyces pombe. MOLECULAR GENETICS AND GENOMICS. 2023. 299. 1. 20
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Books (1)：
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生物の寿命延長 ~老化・長寿命の基盤研究最前線~
(株)エヌ・ティー・エス 2022 ISBN:9784860437732
Lectures and oral presentations (130)：
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分裂酵母の寿命制御因子Ecl1によるTORC1抑制機構の解析
(第47回 日本分子生物学会年会 2024)
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分裂酵母の寿命制御因子Eclファミリーの役割分担と機能解明
(日本農芸化学会中部支部第199回例会 2024)
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分裂酵母に対するTschimganineの生育阻害作用とその標的因子の解析
(日本農芸化学会中部支部第199回例会 2024)
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分裂酵母における小胞体ストレスと細胞長寿命化に関する研究
(日本農芸化学会中部支部第199回例会 2024)
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寿命延長因子eclファミリー遺伝子とカゼインキナーゼ2(CK2)の関連解析
(酵母遺伝学フォーラム第57回研究報告会 2024)
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Education (4)：
- 2009 - 2011 Nagoya University Graduate School of Bioagricultural Sciences
- 2007 - 2009 Nagoya University
- 2003 - 2007 Nagoya University
- 1999 - 2002 中京大学附属中京高等学校
Work history (3)：
- 2012/04 - 現在 Nagoya University Graduate School of Pharmaceutical Sciences Department of Basic Medicinal Sciences Bioscience Assistant Professor
- 2011/05 - 2012/03 Japan Society for Promotion of Science Researcher
- 2009/04 - 2011/04 Japan Society for Promotion of Science Researcher
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