Ichikawa Yuichi

イチカワユウイチ | Ichikawa Yuichi

Affiliation and department：

Research field (5)： Molecular biology , Cell biology , Genomics , Genetics , Structural biochemistry

Research keywords (4)： epigenetics , chromatin , noncoding RNA , 乳がん

Research theme for competitive and other funds (6)：

2022 - 2025 RNAクラウド形成を介した核内長鎖非コードRNAによる新規転写制御機構の解明
2020 - 2022 Mechanisms of transcriptional activation via RNA Cloud formed by ELEANOR noncoding RNAs
2019 - 2020 Defining novel transcriptional regulatory mechanisms via nuclear non-coding RNA involved in breast cancer recurrence
2014 - 2015 出芽酵母人工ミニ染色体を用いたヒトのテロメア領域特異的なヌクレオソーム形成機構の解明
2013 - 2014 減数分裂期における染色体末端集合に必須なタンパク質Bqt1-Bqt2 複合体の構造解析

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Papers (15)：

Megumi Fukuoka, Yuichi Ichikawa, Tomo Osako, Tomoko Fujita, Satoko Baba, Kengo Takeuchi, Nobuyuki Tsunoda, Tomoki Ebata, Takayuki Ueno, Shinji Ohno, et al. The ELEANOR non-coding RNA expression contributes to cancer dormancy and predicts late recurrence of ER-positive breast cancer. Cancer Science. 2022. 113. 7. 2336-2351
Yuichi Ichikawa, Vincent M Bruno, Carol A Woolford, Hannah Kim, Eunsoo Do, Grace C Brewer, Aaron P Mitchell. Environmentally contingent control of Candida albicans cell wall integrity by transcriptional regulator Cup9. Genetics. 2021. 218. 3
Koji Katsumata, Yuichi Ichikawa, Tomohiro Fuse, Hitoshi Kurumizaka, Akio Yanagida, Takeshi Urano, Hiroaki Kato, Mitsuhiro Shimizu. Sequence-dependent nucleosome formation in trinucleotide repeats evaluated by in vivo chemical mapping. Biochemical and Biophysical Research Communications. 2021. 556. 179-184
Risa Fujita, Tatsuro Yamamoto, Yasuhiro Arimura, Saori Fujiwara, Hiroaki Tachiwana, Yuichi Ichikawa, Yuka Sakata, Liying Yang, Reo Maruyama, Michiaki Hamada, et al. Nucleosome destabilization by nuclear non-coding RNAs. Communications Biology. 2020. 3. 1. 60-60
Hidetaka Yuzurihara, Yuuki Aizawa, Mika Saotome, Yuichi Ichikawa, Hiroshi Yokoyama, Yuji Chikashige, Tokuko Haraguchi, Yasushi Hiraoka, Hitoshi Kurumizaka, Wataru Kagawa. Improved Methods for Preparing the Telomere Tethering Complex Bqt1-Bqt2 for Structural Studies. The Protein Journal. 2020. 39. 2. 174-181

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MISC (5)：

山本達郎, 市川雄一, 斉藤典子. ノンコーディングRNAによる3次元ゲノム構造の制御. 生化学. 2021. 93. 1
Yuichi Ichikawa, Paul D. Kaufman. Novel genetic tools for probing individual H3 molecules in each nucleosome. Current Genetics. 2019. 65. 2. 371-377
Yuichi Ichikawa, Paul Kaufman. Biochemical Analysis of Dimethyl Suberimidate-crosslinked Yeast Nucleosomes. BIO-PROTOCOL. 2018. 8. 6
Yuichi Ichikawa, Yoshifumi Nishimura, Hitoshi Kurumizaka, Mitsuhiro Shimizu. Nucleosome organization and chromatin dynamics in telomeres. Biomolecular Concepts. 2015. 6. 1. 67-75
Y. Ichikawa, N. Morohashi, H. Mikai, Y. Nishimura, H. Kurumizaka, M. Shimizu. Nucleosome-disfavoring properties of telomeric repeat sequences in vivo. MOLECULAR BIOLOGY OF THE CELL. 2013. 24

Books (6)：

Cytogenomics 1st Edition, Edited by: Thomas Liehr, Chapter 18- Shaping of genome by long noncoding RNAs
ELSEVIER 2021
実験医学増刊【相分離 : メカニズムと疾患 : “膜のないオルガネラ"はいかに機能するか?】廣瀬哲郎, 加藤昌人, 中川真一・編『染色体座位顆粒』
羊土社 2021 ISBN:9784758103954
Replication mechanisms of non-genomic information
2020
Basic principle of gene expression governed by chromatin and nuclear structure
2020
基礎コース細胞生物学永田恭介・編「5章情報記憶媒体としてのDNA 」
東京化学同人 2013 ISBN:9784807908196

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Lectures and oral presentations (9)：

ELEANOR-chromatin interaction facilitates ESR1 transcription
(The 80th Annual Meeting of the Japanese Cancer Association 2021)
ER陽性乳がんで高発現している非コードRNA Eleanorsを介した転写活性化
(第20回関東ホルモンと癌研究会 2020)
Eleanor RNAクラウドを介した転写活性化
(第37回染色体ワークショップ・第18回核ダイナミクス研究会 2019)
Mechanisms of transcriptional activation mediated by Eleanor RNA cloud in ER-positive breast cancer cells
(2019)
Eleanor RNAクラウドを介した転写活性化機構
(RNAフロンティアミーティング 2019)

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Education (3)：

Work history (9)：

2024/04 - 現在第一三共株式会社
2023/08 - 現在 National Center for Global Health and Medicine
2022/03 - 2024/03 第一三共RDノバーレ株式会社
2018/02 - 2022/02 公益財団法人がん研究会がん研究所がん生物部博士研究員
2016/07 - 2018/02 University of Massachusetts Medical School Department of Molecular, Cell and Cancer Biology Postdoctoral Researcher

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Awards (1)：

2021/12 - EMBO-MBSJ Program “EMBO Reports Poster Award” Long noncoding RNA ELEANOR2 forms RNA cloud and facilitates transcription in ER positive breast cancer cells

Association Membership(s) (2)：

日本癌学会 , 日本分子生物学会

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