Rchr
J-GLOBAL ID：201201031770731271   Update date: Oct. 02, 2024

SAKAI Daisuke

サカイ ダイスケ | SAKAI Daisuke
Affiliation and department：
Kanazawa Medical University Department of Biology

About Kanazawa Medical University Department of Biology


Job title： Associate Professor
Research field  (1)： Developmental biology
Research keywords  (4)： マウス胚 ,  神経堤細胞 ,  顔面発生 ,  脳発生
Research theme for competitive and other funds  (10)：
  • 2023 - 2026 生理的低酸素による抑制性神経の多様化機構
  • 2021 - 2024 低酸素刺激とガレクチンファミリーによる胎盤栄養膜細胞の分化制御機構
  • 2019 - 2022 低酸素シグナルによる抑制性神経の発生制御機構の解明
  • 2017 - 2021 Roles of galectins during trophoblast differentiation into invasive cells
  • 2019 - 2021 低酸素シグナルによる抑制性神経の発生制御機構の解明
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Papers (32)：
  • Miki Matsuoka, Daisuke Sakai, Hiroshi Shima, Toshio Watanabe. Neuron-specific loss of Ppp6c induces neonatal death and decreases the number of cortical neurons and interneurons. Biochemical and biophysical research communications. 2024. 693. 149353-149353
  • Yuki Murakami, Yukio Imamura, Yoshiyuki Kasahara, Chihiro Yoshida, Yuta Momono, Ke Fang, Daisuke Sakai, Yukuo Konishi, Toshimasa Nishiyama. Maternal Inflammation with Elevated Kynurenine Metabolites Is Related to the Risk of Abnormal Brain Development and Behavioral Changes in Autism Spectrum Disorder. Cells. 2023. 12. 7. 1087-1087
  • Daisuke Sakai, Yuki Murakami, Daichi Shigeta, Mitsuhiro Tomosugi, Hiromi Sakata-Haga, Toshihisa Hatta, Hiroki Shoji. Glycolytic activity is required for the onset of neural plate folding during neural tube closure in mouse embryos. Frontiers in cell and developmental biology. 2023. 11. 1212375-1212375
  • Sho Takata, Hiromi Sakata-Haga, Hiroki Shimada, Tsuyoshi Tsukada, Daisuke Sakai, Hiroki Shoji, Mitsuhiro Tomosugi, Yuka Nakamura, Yasuhito Ishigaki, Hideaki Iizuka, et al. LIF-IGF Axis Contributes to the Proliferation of Neural Progenitor Cells in Developing Rat Cerebrum. International journal of molecular sciences. 2022. 23. 21. 13199
  • Karla T. Falcon, Kristin E. N. Watt, Soma Dash, Ruonan Zhao, Daisuke Sakai, Emma L. Moore, Sharien Fitriasari, Melissa Childers, Mihaela E. Sardiu, Selene Swanson, Dai Tsuchiya, Jay Unruh, George Bugarinovic, Lin Li, Rita Shiang, Annita Achilleos, Jill Dixon, Michael Dixon, and Paul A Trainor. Dynamic regulation and requirement for ribosomal RNA transcription during mammalian development. Proceedings of National Academy of Science. 2022. 119(31). 2116974119
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MISC (6)：
  • Murakami Yuki, Imamura Yukio, Sakai Daisuke, Konishi Yukuo. Maternal immune activation related to neurodevelopmental disorder-like phenotype in mouse models. Japanese Journal of Biological Psychiatry. 2021. 32. 3. 120-123
  • OGOH Honami, YAMAGATA Kazutsune, NAKAO Tomomi, SANDELL Lisa L., YAMAMOTO Ayaka, YAMASHITA Aiko, TANGA Naomi, SUZUKI Mai, ABE Takaya, KITABAYASHI Issay, et al. Deregulation of histone methylation is implicated in the etiology of frontonasal dysplasia. 日本先天異常学会学術集会プログラム・抄録集. 2019. 59th
  • Daisuke Sakai, Jun Motoyama, Paul A Trainor. Prevention of the craniofacial abnormalities based on the pathogenesis of Treacher Collins syndrome. Congenital Anomalies. 2015. 55. 4
  • Daisuke Sakai, Jill Dixon, Michael Dixon, Paul A Trainor. Prevention of the craniofacial abnormalities of Treacher Collins syndrome through treatment with antioxidant. Congenital Anomalies. 2013. 53. 4
  • Takashi Suzuki, Daisuke Sakai, Noriko Osumi, Yoshio Wakamatsu. Expression of Sox9-interacting protein SC35/Sfrs2 in avian embryos. FUTURE MEDICAL ENGINEERING BASED ON BIONANOTECHNOLOGY, PROCEEDINGS. 2006. 199-+
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Books (2)：
  • Mammalian Cell Culture, Current Protocols in Essential Laboratory Technique
    John Wiley & Sons 2015
  • Mammalian Cell Culture. Current Protocols in Essential Laboratory Technique
    John Wiley & Sons 2013
Lectures and oral presentations  (22)：
  • 迅速かつ非破壊的な組織透明化法RAPを基盤とする新規プロトコルの開発
    (第64回日本組織細胞化学会総会・学術集会 2023)
  • RAP組織透明化法のin situ hybridizationへの応用
    (第63回日本先天異常学会学術集会 2023)
  • 胎生期マウス由来のニューロスフェアを対象とした組織透明化技術の開発および3次元イメージング手法の検討
    (第63回日本先天異常学会学術集会 2023)
  • 胎盤ACTHの発現誘導における胎盤CRHの作用
    (第 58回北陸生殖医学会 総会・学術講演会 2023)
  • Mechanisms of ACTH induction in mouse trophoblast stem cells by LIF
    (2022)
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Education (1)：
  • - 2001 Tokyo Metropolitan University
Professional career (1)：
  • 理学博士
Work history (6)：
  • 2024/10 - 現在 Kanazawa Medicak University Department of Biology Associate Professor
  • 2019/04 - 2024/09 Kanazawa Medical University Department of Biology Lecture
  • 2012/04 - 2019/03 Doshisha University Graduate School of Brain Science
  • 2010/09 - 2012/03 Nara Institute of Science and Technology
  • 2006/02 - 2010/08 ストワーズ医学研究所(アメリカ) Senior Research Associate
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Committee career (3)：
  • 2022/05 - 現在 Review Editori
  • 2011/08 - 現在 Frontiers in Physiology, Craniofacial Biology Review Editor
  • 2021/04 - 2022/03 金沢医科大学一般教育機構 教養論文集編集委員
Awards (4)：
  • 2024/01 - 金沢医科大学 優良教員賞 Best Researcher Award
  • 2023/07 - 金沢医科大学 金沢医科大学医学会論文表彰
  • 2023/03 - 金沢医科大学 優良教員賞 Best Researcher Award
  • 2011/08 - 第23回 MBL高遠分子細胞生物学シンポジウム 研究奨励賞
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