Kitajima Shunsuke

キタジマシユンスケ | Kitajima Shunsuke

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/90566465.ja.html

Research field (1)： Tumor biology

Research keywords (2)： STING-TBK1経路 , KRAS変異型肺がん

Research theme for competitive and other funds (6)：

2020 - 2023 KRAS/LKB1変異型肺がんが示す免疫チェックポイント阻害薬治療耐性の克服
2020 - 2022 Identification of STING agonist transporter in cancer cells by utilizing a lineage barcoding system
2014 - 2017 Regulation of metabolism by RB tumor suppressor gene
2014 - 2016 Inflammatory circuit that triggres malignant progression
2013 - 2015 CCL2 induced by RB inactivation contributes to the formation of tumor-promoting inflammatory microenvironment

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Papers (39)：

Tetsuo Tani, Haritha Mathsyaraja, Marco Campisi, Ze-Hua Li, Koji Haratani, Caroline G Fahey, Keiichi Ota, Navin R Mahadevan, Yingxiao Shi, Shin Saito, et al. TREX1 inactivation unleashes cancer cell STING-interferon signaling and promotes anti-tumor immunity. Cancer discovery. 2024
谷哲夫, 北嶋俊輔, 吉田遼平, Barbie David. 稀少ドライバー変異 KRAS変異陽性肺癌でのSTING経路活性化を介した新規治療法の検討. 日本呼吸器学会誌. 2023. 12. 増刊. 191-191
Christopher Noyes, Shunsuke Kitajima, Fengkai Li, Yusuke Suita, Saradha Miriyala, Shakson Isaac, Nagib Ahsan, Erik Knelson, Amir Vajdi, Tetsuo Tani, et al. The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells. Communications Biology. 2023. 6. 1
Shunsuke Kitajima, Tetsuo Tani, Benjamin F Springer, Marco Campisi, Tatsuya Osaki, Koji Haratani, Minyue Chen, Erik H Knelson, Navin R Mahadevan, Jessica Ritter, et al. MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer. Cancer cell. 2022. 40. 10. 1128-1144
Ryohei Yoshida, Maria Saigi, Tetsuo Tani, Benjamin F Springer, Hirofumi Shibata, Shunsuke Kitajima, Navin R Mahadevan, Marco Campisi, William Kim, Yoshihisa Kobayashi, et al. MET-induced CD73 restrains STING-mediated immunogenicity of EGFR-mutant lung cancer. Cancer research. 2022. 82. 21. 4079-4092

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MISC (23)：

Shunsuke Kitajima, Fengkai Li, Chiaki Takahashi. Tumor milieu controlled by RB tumor suppressor. International Journal of Molecular Sciences. 2020. 21. 7
D Thumkeo, Y Katsura, Y Nishimura, P Kanchanawong, K Tohyama, T Ishizaki, S Kitajima, C Takahashi, T Hirata, N Watanabe, et al. mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse. Science advances. 2020. 6. 1. eaay2432
Fengkai Li, Shunsuke Kitajima, Naofumi Mukaida, Chiaki Takahashi. Rb inactivation enhances tumor progression by elevating CCL2 expression. CYTOKINE. 2017. 100. 189-190
Shunsuke Kitajima, Chiaki Takahashi. Intersection of retinoblastoma tumor suppressor function, stem cells, metabolism, and inflammation. CANCER SCIENCE. 2017. 108. 9. 1726-1731
河野晋, 村中勇人, 北嶋俊輔, 佐々木信成, 鈴木美砂, 髙橋智聡. RBとがんの代謝. 実験医学(増刊号). 2017. 35. 10. 21-25

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Education (1)：

Work history (4)：

Association Membership(s) (2)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE CANCER ASSOCIATION

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