Rchr
J-GLOBAL ID：201201036108439740
Update date: Oct. 29, 2024
Tawarayama Hiroshi
Tawarayama Hiroshi
Affiliation and department：
Research field (1)：
Neuroscience - general
Research theme for competitive and other funds (7)：
- 2023 - 2026 グルタチオン三硫化物GSSSGの抗酸化・抗炎症作用に基づく難治性眼疾患の病態制御
- 2023 - 2026 STING経路に着目した滲出型加齢黄斑変性の網膜下線維化の病態解明
- 2021 - 2024 炎症性眼疾患の治療・緩和を見据えた活性イオウ分子種による抗炎症作用機序の解明
- 2018 - 2021 Development of a HDAC1/2 inhibitor K560-mediated treatment for glaucoma
- 2015 - 2018 The roles of the chamorepellent draxin in hippocampal neurogenesis
- 2015 - 2016 癲癇モデルマウスを用いたタキシフェン 誘導 体リダイフェン-D による神経保護効果の検討
- 2013 - 2015 Roles of draxin in hippocampal development as a neurotrophic factor
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Papers (26)：
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Hiroshi Tawarayama, Keiko Uchida, Hirokazu Hasegawa, Masaaki Yoshida, Maki Inoue-Yanagimachi, Wataru Sato, Noriko Himori, Masayuki Yamamoto, Toru Nakazawa. Estrogen, via ESR2 receptor, prevents oxidative stress-induced Müller cell death and stimulates FGF2 production independently of NRF2, attenuating retinal degeneration. Experimental Eye Research. 2024. 248
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内田 惠子, 檜森 紀子, 吉田 真彰, 俵山 寛司, 佐藤 孝太, 中澤 徹. Nrf2欠損Mueller細胞はエストロゲン受容体β発現上昇を介して抗炎症効果が増強する. 日本眼科学会雑誌. 2024. 128. 臨増. 204-204
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Hiroshi Tawarayama, Kota Umeki, Maki Inoue-Yanagimachi, Naoki Takahashi, Hirokazu Hasegawa, Noriko Himori, Satoru Tsuda, Hiroshi Kunikata, Takaaki Akaike, Toru Nakazawa. Glutathione trisulfide prevents lipopolysaccharide-induced retinal inflammation via inhibition of proinflammatory cytokine production in glial cells. Scientific reports. 2023. 13. 1. 11513-11513
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Hiroshi Tawarayama, Yoshiyuki Hirata, Uchida Keiko, Noriko Himori, Shinichi Uesato, Toru Nakazawa. Isozyme-specific Histone Deacetylase 1/2 Inhibitor K560 Attenuates Oxidative Stress-induced Retinal Cell Death. Neuroscience letters. 2022. 793. 136978-136978
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Maki Inoue-Yanagimachi, Noriko Himori, Keiko Uchida, Hiroshi Tawarayama, Kota Sato, Masayuki Yamamoto, Kazuhiko Namekata, Takayuki Harada, Toru Nakazawa. Changes in glial cells and neurotrophic factors due to rotenone-induced oxidative stress in Nrf2 knockout mice. Experimental eye research. 2022. 226. 109314-109314
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MISC (3)：
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佐藤大夢, 石川誠, 大石路子, 神位りえ子, 佐藤孝太, 俵山寛司, 中澤徹. Changes in NLRP3 modulated by microglia in a rat ex vivo glaucoma model. 日本眼科学会雑誌. 2024. 128
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佐藤孝太, 藤田幸輔, 俵山寛司, 片山翔太, 西口康二, 中澤徹. AAV2-CRISPR/Cas9システムを用いた網膜神経節細胞のゲノム編集. 日本眼科学会雑誌. 2019. 123
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國方彦志, 佐藤孝太, 俵山寛司, 中澤徹. 先進感覚器研究コアセンターの感覚器研究プロジェクト. ファルマシア(Web). 2018. 54. 11. 1025-1029(J-STAGE)
Professional career (1)：
- Ph.D. (Tohoku University)
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