Rchr
J-GLOBAL ID:201201041406375210   Update date: Nov. 17, 2024

Sato Takashi

サトウ タカシ | Sato Takashi
Affiliation and department:
Job title: Specially appointed professor
Other affiliations (2):
  • 富士電機株式会社 半導体事業本部  松本工場    健康管理センター所長
  • Yokohama City University  Department of Pulmonology, School of Medicine  
Homepage URL  (1): https://www.ingentaconnect.com/content/sil/impact/2019/00002019/00000003/art00022
Research field  (1): Respiratory medicine
Research keywords  (3): ナノ粒子 ,  免疫調節性DNA ,  免疫制御
Research theme for competitive and other funds  (11):
  • 2022 - 2025 Development of genetically modified lactococcus lactis-based mucosal vaccines/drugs for COVID-19
  • 2020 - 2024 経口用乳酸菌オリゴDNA微粒子の最適化と腸管上皮を起点とする免疫制御機構の解明
  • 2019 - 2024 Innovative therapy for lung cancer: prophylaxis and therapy by intratracheal delivery of probiotics harboring immune checkpoint-blocking single-chain variable fragment
  • 2020 - 2022 Development of smart lactic acid bacteria
  • 2017 - 2021 Study on the immune mechanism using oral nanocapsule with oligodeoxynucleotides from lactic acid bacteria
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Papers (85):
  • Masahiro Yoda, Shogo Takase, Kaho Suzuki, Aito Murakami, Fu Namai, Takashi Sato, Tadashi Fujii, Takumi Tochio, Takeshi Shimosato*. Development of engineered IL-36γ-hypersecreting Lactococcus lactis to improve the intestinal environment. World Journal of Microbiology and Biotechnology. 2024. in press
  • Aito Murakami, Haruka Yamaguchi, Fu Namai, Takashi Sato, Maki Yamazaki, Hiroshi Uehara, Tadashi Fujii, Takumi Tochio, Kunihiro Shiomi, Takeshi Shimosato. Ad libitum feeding of silkworm larvae powder-containing diets specifically influences metabolism-related and short-chain fatty acid-producing gut bacteria in mice. Frontiers in cellular and infection microbiology. 2024. 14. 1383774-1383774
  • Aito Murakami, Koharu Toyomoto, Fu Namai, Takashi Sato, Tadashi Fujii, Takumi Tochio, Takeshi Shimosato. Oral administration of Brevibacterium linens from washed cheese increases the proportions of short-chain fatty acid-producing bacteria and lactobacilli in the gut microbiota of mice. Animal Science Journal. 2023. 94. 1
  • Taishi Onodera, Nicolas Sax, Takashi Sato, Yu Adachi, Ryutaro Kotaki, Takeshi Inoue, Ryo Shinnakasu, Takayuki Nakagawa, Shuetsu Fukushi, Tommy Terooatea, et al. CD62L expression marks SARS-CoV-2 memory B cell subset with preference for neutralizing epitopes. Science Advances. 2023. 9. 24
  • Masahiro Shinoda, Shinichiro Ota, Yuto Yoshida, Takatomo Hirouchi, Kanako Shinada, Takashi Sato, Miwa Morikawa, Naoki Ishii, Masaharu Shinkai. High Fever, Wide Distribution of Viral Pneumonia, and Pleural Effusion are More Critical Findings at the First Visit in Predicting the Prognosis of COVID-19: A Single Center, retrospective, Propensity Score-Matched Case-Control Study. International Journal of General Medicine. 2023. Volume 16. 2337-2348
more...
MISC (14):
  • Kaho Suzuki, Fu Namai, Aito Murakami, Yuichi Sato, Akihiro Kotsugai, Takeshi Shimosato, Takashi Sato. Intratracheal therapy using nintedanib amorphous particles in murine pulmonary fibrosis. European Respiratory Journal. 2024. 64. suppl 68. OA4557-OA4557
  • K. Suzuki, F. Namai, N. Nomura, Y. Sato, A. Kotsugai, T. Shimosato, T. Sato. Effect of Local Intratracheal Therapy Using Particleized Nintedanib in a Murine Model of Pulmonary Fibrosis. D29. TRANSLATIONAL RESEARCH IN IPF. 2023. 207. A6476
  • N. Nomura, F. Namai, T. Sato, T. Shimosato. Intranasal Administration of Genetically Modified Lactococcus Lactis Producing PD-L1 scFv Improves Survival in Lung Cancer Model Mice. C70. COPD (AND LUNG CANCER) CLINICAL AND TRANSLATIONAL STUDIES. 2023. 207. A5754
  • Kentaro Nakashima, Yu Hara, Takashi Sato, Masaharu Shinkai, Takeshi Kaneko. A Case of Adenocarcinoma of the Lung With EGFR T790 Mutation Presenting With Chylous Ascites. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2018. 13. 8. 1227-1228
  • T. Sato, K. Nakashima, Y. Shibata, H. Sasaki, M. Ikeda, A. Nagashima, H. Watanabe, K. Nagai, H. Nagakura, N. Horita, et al. Toll-Like Receptor 9, A Key To Attenuate Disease Progression In A Murine Model Of COPD. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2017. 195
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Patents (4):
  • PHARMACEUTICAL COMPOSITION
  • Polyketal particles including a CpG oligodeoxynucleotide for the treatment of lung cancer
  • Use of CpG oligodeoxynucleotides to induce epithelial cell growth
  • Method of treating pneumoconiosis with oligodeoxy- nucleotides
Books (7):
  • Innovative therapy for lung cancer - intratracheal delivery of probiotics harboring immune checkpoint-blocking single-chain variable fragment -
    2024
  • Development of microbial therapeutics for the prevention/suppression of cancer and beyond
    2024
  • Innovative therapy for lung cancer - intratracheal delivery of probiotics harboring immune checkpoint-blocking single-chain variable fragment -
    BIO Clinica 2023;38(7):638-42 2023
  • Book title: Chronic Obstructive Pulmonary Disease - A Compendium of Medicine and the Humanities
    IntechOpen 2022 ISBN:9781803567679
  • Development of a New Treatment Modality for Lung Diseases That Uses Innovative Fine Droplet Drying (FDD) Technology Offering Inhalable Nano/microparticles-incorporated Therapeutic Agents
    Science Impact Ltd 2019
more...
Lectures and oral presentations  (5):
  • Intratracheal therapy using oligodeoxynucleotides and/or genetically modified lactic acid bacteria-derived biological molecules
    (The Korean Society of Toxicology/The Korean Environmental Mutagen Society 2022 KSOT/KEMS Spring International Symposium 2022)
  • Innovative therapy for lung cancer ~Intratracheal delivery of nanomicroparticles-incorporated immune checkpoint-blocking single-chain variable fragment~
    (NIH/NCI Symposium on Innate Immunity & Modulation of the Host Immune Response in Honor of the Career of Dr. Dennis Klinman 2019)
  • 吸入治療イノベーション~吸入薬で肺癌の制御を目指す研究開発の取り組み~
    (横浜市立大学先端医科学研究センター 第54回市民講座 2018)
  • Intratracheal delivery of immunostimulatory oligonucleotides using biodegradable polyketal nanoparticles: effect of long-term immune responses on murine lung cancer
    (THE 14TH US-JAPAN SYMPOSIUM ON DRUG DELIVERY SYSTEMS 2017)
  • Intratracheal delivery of immunostimulatory oligonucleotides using biodegradable polyketal nanoparticles: effect on murine lung cancer
    (THE 13TH US-JAPAN SYMPOSIUM ON DRUG DELIVERY SYSTEMS 2015)
Education (3):
  • 2002 - 2006 Yokohama City University Graduate School of Medicine Department of Internal Medicine and Clinical Immunology
  • 1994 - 2000 Yokohama City University School of Medicine
  • 1990 - 1994 Tokyo Instutute of Technology School of Engineering Department of Mechano-Aerospace Engineering
Professional career (2):
  • 博士(医学) (横浜市立大学)
  • Bachelor of Engineering (Tokyo Institute of Technology)
Work history (12):
  • 2024/04 - 現在 富士電機株式会社 半導体事業本部 松本工場 健康管理センター所長
  • 2022/04 - 現在 富士電機株式会社 半導体事業本部 松本工場 専属産業医
  • 2020/04 - 現在 Yokohama City University Department of Pulmonology, School of Medicine
  • 2019/08 - 現在 Shinshu University Interdisciplinary Cluster for Cutting Edge Research
  • 2020/04 - 2022/03 Tokyo Shinagawa Hospital Head of Medical Oncology Department/Director of Research Center
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Committee career (3):
  • 2017/04 - 2020/04 日本呼吸器学会 国際委員会委員
  • 2012/04 - 2015/05 米国胸部疾患学会(American Thoracic Society) プログラム委員
  • 2008/04 - 2010/05 米国胸部疾患学会(American Thoracic Society) プログラム委員
Awards (6):
  • 2013/11 - National Institute of Health Fellows Award for Research Excellence (FARE) 2014
  • 2013/04 - 米国国立衛生研究所 Appreciation Award
  • 2009/01 - 横浜市立大学第一内科同門会賞
  • 2008/10 - 神奈川難病財団研究奨励賞
  • 2007/05 - The Oak Ridge Institute for Science and Education (ORISE) Research Award
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