Research keywords (8):
Netherton syndrome
, atopic dermatitis
, psoriasis
, LEKTI
, kallikrein-related peptidases
, antimicrobial peptides
, epidermal keratinocytes
, Innate immunity in the skin
Research theme for competitive and other funds (11):
2023 - 2026 Elucidation of the pathogenesis of Netherton syndrome using model mice
2023 - 2026 高深度プロテオーム解析による悪性黒色腫血中腫瘍マーカーの探索と臨床応用
2023 - 2026 Mechanisms of reciprocal regulation of immune diseases by EBI3-containing heterodimer cytokines
2020 - 2023 乾癬病変部表皮角化細胞産生EBI3含有サイトカインに関する研究
2016 - 2018 the elucidation of complication mechanism in patients with recessive dystrophic epidermolysis bullosa (RDEB)
2014 - 2017 The analysis of regulation of serine protease inhibitors expression in epidermal keratinocytes
2012 - 2015 Studies on host immune responses induced by reactivation of EB virus-infected lymphocytes and resultant skin lesions
2012 - 2014 The effect of aberrant expression of kallikrein 7 induced by Th2 cytokines on epidermal barrier
2011 - 2013 Investigation of expression regulation and pathological mechanism of Panton-valentine leukocidine in skin
2010 - 2011 Preferable biological milieu for the growth of viral epithelial neoplasms and its regulation
2010 - 2011 An effect of Th2 environment on kallikrein expression in keratinocytes and skin barrier
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Papers (133):
Tomoko Miyake, Takenobu Yamamoto, Yoji Hirai, Takahide Takahashi, Takuya Furuhashi, Hisashi Nomura, Yoshio Kawakami, Shin Morizane. Monokine induced by gamma interferon levels in plasma might be a diagnostic marker of Hydroa vaccniforme lymphoproliferative disorder systemic form. Journal of the American Academy of Dermatology. 2024
Hitoshi Urakami, Soichiro Yoshikawa, Kei Nagao, Kensuke Miyake, Yuki Fujita, Ayaka Komura, Miho Nakashima, Ryusuke Umene, Shuhei Sano, Zheyu Hu, et al. Stress-experienced monocytes/macrophages lose anti-inflammatory function via β2-adrenergic receptor in skin allergic inflammation. Journal of Allergy and Clinical Immunology. 2024
Shogo Ikezawa, Emi Yokoyama, Hitoshi Urakami, Mikiko Takigawa, Tomoko Miyake, Yoji Hirai, Yoshio Kawakami, Shin Morizane. A case of anaphylaxis to kumquat (Citrus japonica). European journal of dermatology : EJD. 2024. 34. 5. 539-541
Kei Nagao, Soichiro Yoshikawa, Hitoshi Urakami, Yuki Fujita, Ayaka Komura, Miho Nakashima, Masatsugu Oh-Hora, Atsushi Fujimura, Takeshi Y Hiyama, Keiji Naruse, et al. Ligand-independent function of β2-adrenergic receptor affects IgE-mediated Ca2+ influx in mast cells. Biochemical and biophysical research communications. 2024. 733. 150595-150595
Yoshihiro Matsuda, Tomoko Miyake, Hironobu Toda, Kota Tachibana, Hayato Nomura, Yoji Hirai, Yoshio Kawakami, Naoya Sakoda, Shin Morizane. The treatment effect of endovascular therapy for chronic limb-threatening ischemia with systemic sclerosis. The Journal of dermatology. 2024. 51. 8. 1108-1112