Research keywords (8):
Netherton syndrome
, atopic dermatitis
, psoriasis
, LEKTI
, kallikrein-related peptidases
, antimicrobial peptides
, epidermal keratinocytes
, Innate immunity in the skin
Research theme for competitive and other funds (11):
2023 - 2026 Elucidation of the pathogenesis of Netherton syndrome using model mice
2023 - 2026 高深度プロテオーム解析による悪性黒色腫血中腫瘍マーカーの探索と臨床応用
2023 - 2026 Mechanisms of reciprocal regulation of immune diseases by EBI3-containing heterodimer cytokines
2020 - 2023 乾癬病変部表皮角化細胞産生EBI3含有サイトカインに関する研究
2016 - 2018 the elucidation of complication mechanism in patients with recessive dystrophic epidermolysis bullosa (RDEB)
2014 - 2017 The analysis of regulation of serine protease inhibitors expression in epidermal keratinocytes
2012 - 2015 Studies on host immune responses induced by reactivation of EB virus-infected lymphocytes and resultant skin lesions
2012 - 2014 The effect of aberrant expression of kallikrein 7 induced by Th2 cytokines on epidermal barrier
2011 - 2013 Investigation of expression regulation and pathological mechanism of Panton-valentine leukocidine in skin
2010 - 2011 Preferable biological milieu for the growth of viral epithelial neoplasms and its regulation
2010 - 2011 An effect of Th2 environment on kallikrein expression in keratinocytes and skin barrier
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Papers (129):
Kei Nagao, Soichiro Yoshikawa, Hitoshi Urakami, Yuki Fujita, Ayaka Komura, Miho Nakashima, Masatsugu Oh-Hora, Atsushi Fujimura, Takeshi Y Hiyama, Keiji Naruse, et al. Ligand-independent function of β2-adrenergic receptor affects IgE-mediated Ca2+ influx in mast cells. Biochemical and biophysical research communications. 2024. 733. 150595-150595
Yoshihiro Matsuda, Tomoko Miyake, Hironobu Toda, Kota Tachibana, Hayato Nomura, Yoji Hirai, Yoshio Kawakami, Naoya Sakoda, Shin Morizane. The treatment effect of endovascular therapy for chronic limb-threatening ischemia with systemic sclerosis. The Journal of dermatology. 2024. 51. 8. 1108-1112
Yuko Fujimoto, Yoshio Kawakami, Tomoko Miyake, Yoji Hirai, Masahiro Tabata, Shin Morizane. Acquired generalized anhidrosis following durvalumab treatment in a patient with advanced non-small cell lung cancer. The Journal of dermatology. 2024
Yoji Hirai, Jun Sakurai, Shiho Yoshida, Takashi Kikuchi, Toshiharu Mitsuhashi, Tomoko Miyake, Taku Fujimura, Riichiro Abe, Hiroki Fujikawa, Hikari Boki, et al. Phase I/II clinical trial of brentuximab vedotin for pretreated Japanese patients with CD30-positive cutaneous T-cell lymphoma. The Journal of dermatology. 2024. 51. 8. 1037-1049
Masaya Kawamoto, Yoshio Kawakami, Yoji Hirai, Saya Kubota, Hideaki Fujiwara, Yayoi Ueda, Kazushi Anzawa, Yoshinobu Maeda, Shin Morizane. Disseminated Lomentospora prolificans infection presenting with multiple cutaneous lesions in an immunocompromised host: A case report and literature review. The Journal of dermatology. 2024