Okita Riki

Homepage URL (1)： http://www.yamaguchi-hosp.jp/wp/wp-content/uploads/2018/04/HP-腫瘍免疫%E3%80%80宇部.pdf

Research field (3)： Immunology , Respiratory surgery , Cardiovascular surgery

Research keywords (3)： Surgical Oncology , Tumor Immunology , General thoracic surgery

Research theme for competitive and other funds (5)：

2022 - 2025 Study for regulation mechanism of immunomodulatory molecules which are therapeutic targets for malignant pleural mesothelioma
2019 - 2023 悪性胸膜中皮腫に対するNK細胞に関連した免疫調節分子の発現制御療法の開発
2016 - 2020 Immunoescape mechanisms of thoracic malignancy via EGFR signaling
2013 - 2015 Immunoescape from innnate/adoptive antitumor immunity via EGF family receptor in non-small cell lung cancer
2012 - 2013 非小細胞肺癌におけるHERシグナルを介した自然免疫逃避機構の解明

Papers (111)：

Akira Tanaka, Riki Okita, Takushi Morishige, Masanori Okada, Hidetoshi Inokawa, Katsutoshi Hirazawa, Kaori Kameyama, Akihiko Ikeda, Eiji Ikeda. A case of primary lung adenocarcinoma mimicking metastatic papillary thyroid carcinoma. Thoracic cancer. 2023
Riki Okita, Nobutaka Kawamoto, Masanori Okada, Hidetoshi Inokawa, Naoki Yamamoto, Tomoyuki Murakami, Eiji Ikeda. Preoperative neutrophil-to-lymphocyte ratio correlates with PD-L1 expression in immune cells of patients with malignant pleural mesothelioma and predicts prognosis. Scientific Reports. 2023. 13. 1
Riki Okita, Nobutaka Kawamoto, Masanori Okada, Hidetoshi Inokawa, Naoki Yamamoto, Tomoyuki Murakami, Eiji Ikeda. Preoperative neutrophil-to-lymphocyte ratio correlates with PD-L1 expression in immune cells of patients with malignant pleural mesothelioma and predicts prognosis. Scientific reports. 2023. 13. 1. 5263-5263
Riki Okita, Yuka Mimura-Kimura, Nobutaka Kawamoto, Naoki Yamamoto, Masashi Umeda, Masanori Okada, Hidetoshi Inokawa, Yusuke Mimura, Tomoyuki Murakami, Masao Nakata, et al. Effects of tumor-infiltrating CD8+ T cells, PD1/PD-L1 axis, and expression patterns of HLA class I on the prognosis of patients with malignant pleural mesothelioma who underwent extra-pleural pneumonectomy. Cancer immunology, immunotherapy : CII. 2022
Nobutaka Kawamoto, Riki Okita, Masanori Okada, Kosuke Ito, Katsutoshi Hirazawa, Hidetoshi Inokawa. Fibrin glue-induced eosinophilic pleural effusion after pulmonary resection: A case report. International Journal of Surgery Case Reports. 2021. 85

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MISC (45)：

木下征也, 沖田理貴, 野島雄史, 最相晋輔, 清水克彦, 中田昌男, 鹿股直樹. 脱落膜型悪性胸膜中皮腫の一例. 日本臨床外科学会雑誌. 2018. 79. 6. 1340-1340
R. Okita, A. Maeda, T. Yukawa, K. Shimizu, Y. Nojima, S. Saisho, M. Nakata. Survival of non-small cell lung cancer patients predicted from expression of PD-L1, HLA class I and MICA/B on tumor cells. ANNALS OF ONCOLOGY. 2017. 28
Yuji Nojima, Katsuhiko Shimizu, Ai Maeda, Shinsuke Saisho, Riki Okita, Masao Nakata. Clinicopathological and Immunohistochemical Features in Lung Invasive Mutinous Adenocarcinoma According to Computed Tomography Findings. JOURNAL OF THORACIC ONCOLOGY. 2017. 12. 1. S1123-S1123
R. Okita, Y. Nojima, A. Maeda, S. Saisho, K. Shimizu, M. Nakata. Repeated exposure to cisplatin enhances NK cell-mediated cytotoxicity via up-regulation of NKG2D ligands in non-small cell lung cancer cells. ANNALS OF ONCOLOGY. 2016. 27
R. Okita, T. Yukawa, Y. Nojima, A. Maeda, S. Saisho, K. Shimizu, M. Nakata. Overexpression of NK cell-activating ligand MICA/B correlates with superior outcomes and might be a therapeutic target for chemo-immunotherapy in non-small-cell lung cancer. ANNALS OF ONCOLOGY. 2015. 26. 149-150

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Work history (10)：

2018/04 - 現在 NHO Yamaguchi Ube Medical Center Thoracic Surgery chief physician
2012/04 - 2018/03 Kawasaki Medical School General Thoracic Surgery
2009/05 - 2012/03 Karolinska Institutet Oncology-Pathology post doc
2008/04 - 2009/04 Hiroshima Univ. Research Institute for Radiation Biology and Medicine Surgical Oncology Assistant professor
2007/10 - 2008/03 広島大学がん治療学特任助教

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Awards (1)：

2006/12 - 日本バイオセラピィ学会優秀演題賞

Association Membership(s) (8)：

日本乳癌学会 , THE JAPAN LUNG CANCER SOCIETY , JAPAN SOCIETY OF CLINICAL ONCOLOGY , ESMO , JSMO , THE JAPANESE ASSOCIATION FOR THORACIC SURGERY , THE JAPANESE ASSOCIATION FOR CHEST SURGERY , JAPAN SURGICAL SOCIETY

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