Rchr
J-GLOBAL ID:201201047168327773
Update date: Aug. 23, 2024
DAISUKE KIMURA
キムラ ダイスケ | DAISUKE KIMURA
Affiliation and department:
Other affiliations (1):
Research field (4):
Hygiene and public health (non-laboratory)
, Hygiene and public health (laboratory)
, Immunology
, Parasitology
Research keywords (8):
感染症
, 免疫
, マラリア
, 寄生虫
, 免疫抑制
, 免疫記憶
, T細胞
, IL-27
Research theme for competitive and other funds (16):
- 2022 - 2023 脱脂米糠のアレルギー抑制効果の検討
- 2019 - 2023 マラリアにおける免疫記憶抑制 ーIL-27依存的細胞死のメカニズム解明ー
- 2019 - 2022 Studies on the role of Plasmodium-specific Tr27 cells in infection regulation and on their antigen recognition
- 2016 - 2019 Induction mechanisms and the regulatory roles of IL-27-producing regulatory T cells during malaria infection
- 2016 - 2019 Interleukin-27-dependent loss of CD4 T cell-memory during malaria infection
- 2015 - 2018 Study on the balance between protective and regulatory immune responses that determine the pathogenesis of malaria infection in the endemic region of Kenya
- 2016 - 2017 マラリア感染後におけるIL-27依存的免疫記憶抑制機序の解明
- 2016 - 2017 ヒトマラリアに認められる免疫抑制の調査研究(ケニア)
- 2013 - 2016 Role of novel regulatory T cells in malaria
- 2013 - 2014 IL-2補助療法による抗マラリア原虫防御免疫の増強と脳マラリア発症阻止
- 2009 - 2011 Inhibition of CD4+ T cell function during infection with malaria parasite
- 2011 - マラリア原虫感染中に誘導される制御性CD4+ T細胞が産生する抑制因子の解析
- 2009 - 2010 マラリア原虫感染中に誘導される制御性CD4+T細胞が産生する抑制因子の同定
- 2010 - マラリア原虫感染中に誘導される制御性CD4+T細胞が産生する抑制因子の同定
- 2007 - 2008 Host effector mechanisms against malaria infection -Study using recombinant parasites expressing model antigens-
- 2008 - マラリア原虫感染により誘導される新規制御性CD4+ T細胞の解析
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Papers (46):
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Sanjaadorj Tsogtsaikhan, Shin-Ichi Inoue, Ganchimeg Bayarsaikhan, Maria Lourdes Macalinao, Daisuke Kimura, Mana Miyakoda, Masahiro Yamamoto, Hiromitsu Hara, Hiroki Yoshida, Katsuyuki Yui. Regulation of memory CD4+ T cell generation by intrinsic and extrinsic IL-27 signaling during malaria infection. International immunology. 2024
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Ahmad Syihan Mat Udin, Shigehiko Uni, Jules Rodrigues, Coralie Martin, Kerstin Junker, Takeshi Agatsuma, Van Lun Low, Weerachai Saijuntha, Hasmahzaiti Omar, Nur Afiqah Zainuri, et al. Redescription, molecular characterisation and Wolbachia endosymbionts of Mansonella (Tupainema) dunni (Mullin & Orihel, 1972) (Spirurida: Onchocercidae) from the common treeshrew Tupaia glis Diard & Duvaucel (Mammalia: Scandentia) in Peninsular Malaysia. Current Research in Parasitology & Vector-Borne Diseases. 2024. 5. 100154
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Maria Lourdes Macalinao, Shin-Ichi Inoue, Sanjaadorj Tsogtsaikhan, Hirotaka Matsumoto, Ganchimeg Bayarsaikhan, Jiun-Yu Jian, Kazumi Kimura, Yoshiaki Yasumizu, Tsuyoshi Inoue, Hiroki Yoshida, et al. IL-27 produced during acute malaria infection regulates Plasmodium-specific memory CD4+ T cells. EMBO molecular medicine. 2023. e17713
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Shigehiko Uni, Ahmad Syihan Mat Udin, Poai Ean Tan, Jules Rodrigues, Coralie Martin, Kerstin Junker, Takeshi Agatsuma, Van Lun Low, Yvonne Ai-Lian Lim, Weerachai Saijuntha, et al. Description and molecular characterisation of Pelecitus copsychi Uni, Mat Udin & Martin n. sp. (Nematoda: Onchocercidae) from the white-rumped shama Copsychus malabaricus (Scopoli) (Passeriformes: Muscicapidae) of Pahang, Malaysia. Current Research in Parasitology & Vector-Borne Diseases. 2022. 2. 100078-100078
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Mbaya Ntita, Shin-Ichi Inoue, Jiun-Yu Jian, Ganchimeg Bayarsaikhan, Kazumi Kimura, Daisuke Kimura, Mana Miyakoda, Eriko Nozaki, Takuya Sakurai, Daniel Fernandez-Ruiz, et al. Type I interferon production elicits differential CD4+ T-cell responses in mice infected with Plasmodium berghei ANKA and P. chabaudi. International immunology. 2022. 34. 1. 21-33
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MISC (14):
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木村 大輔, 都田 真奈, 中前 早百合, Sukhbaatar Odsuren, 木村 一美, Bayarsaikhan Ganchimeg, Akbari Maoud, 原 博満, 吉田 裕樹, 由井 克之. 生体防御研究の新展開〜宿主免疫 vs 病原体の多彩な攻防戦略〜 Interleukin-27はマラリア感染中にCD4+T細胞機能を調節する(Interleukin-27 regulate the function of CD4+ T cells during malaria infection). 日本細菌学雑誌. 2018. 73. 1. 18-18
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Daisuke Kimura, Sayuri Nakamae, Odsuren Sukhbaatar, Mana Miyakoda, Masoud Akbari, Kazumi Kimura, Hiromitsu Hara, Hiroki Yoshida, Katsuyuld Yui. Interleukin-27 inhibits the generation of memory CD4+T cells during malaria infection. CYTOKINE. 2017. 100. 46-46
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都田真奈, 木村大輔. マラリア原虫感染とT細胞反応. Bio Clinica. 2017. 6. 2. 134-137-137
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KAN Kun’u, MIYAKODA Mana, BAYARSAIKHAN Ganchimeg, AKBARI Masoud, KIMURA Kazumi, KIMURA Daisuke, YUI Katsuyuki. IRF4+ dendritic cells play pivotal roles for the induction of protective immunity against infection with Plasmodium chabaudi. 日本寄生虫学会大会プログラム・抄録集. 2017. 86th
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特集 I.サイトカインによる生体応答制御 IL-27による免疫抑制. 2017. 67. 1. 23-29
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Books (3):
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米の機能性食品化と新規利用技術・高度加工技術の開発
テクノシステム 2022 ISBN:9784924728929
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寄生虫学研究 -材料と方法- (再掲)
三恵社 2012
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虫の知らせ
三恵社 2002
Lectures and oral presentations (129):
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メトホルミンによるマラリア原虫排除亢進メカニズムの解明
(第86回日本寄生虫学会大会 2017)
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マラリア原虫治癒後における免疫記憶消失はIL-27依存的である
(第86回日本寄生虫学会大会 2017)
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Plasmodium chabaudi chabaudi感染治癒マウスのP. barghei ANKA感染に対する交叉保護作用
(第86回日本寄生虫学会大会 2017)
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Plasmodium berghei感染マウスの脾臓における抗原特異的CD8+ T細胞動態の解析
(第86回日本寄生虫学会大会 2017)
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IRF+ dendritic cells play pivotal roles for the induction of protective immunity against infection with Plasmodium chabaudi
(第86回日本寄生虫学会大会 2017)
more...
Education (3):
- 2002 - 2005 Kobe University Graduate School, Division of Medical Sciences
- 1999 - 2001 Kobe University Graduate School, Division of Medical Sciences
- 1994 - 1998 Osaka Institute of Technology Faculty of Engineering
Work history (7):
Committee career (2):
- 2015/07 - 現在 日本寄生虫学会 情報処理広報委員、コンサルテーション担当
- 日本寄生虫学会 評議員
Association Membership(s) (3):
日本栄養・食糧学会
, 日本寄生虫学会
, 日本免疫学会
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