Hirono Moritoshi

ヒロノモリトシ | Hirono Moritoshi

Affiliation and department：
Homepage URL (1)： https://nrid.nii.ac.jp/nrid/1000030318836/

Research field (3)： Clinical pharmacy , Physiology , Neuroscience - general

Research keywords (18)： ghrelin , 代謝調節型受容体 , GABA_B受容体 , ホスホリパーゼC , mGluR1 , チロシンキナーゼ , 小脳 , 長期抑圧現象 , 小脳長期抑圧現象 , 小脳皮質 , アドレナリン受容体 , NO , ホスファチジルイノシトール二リン酸 , 瞬目反射学習 , LTD , 連合学習 , 抑制性介在ニューロン , 抑制性シナプス伝達

Research theme for competitive and other funds (9)：

2022 - 2025 グレリン様作用薬による神経機能促進と小脳失調改善への寄与
2019 - 2022 ペリニューロナルネットによる機能的なシナプス伝達モジュレーションの解明
2016 - 2019 Noval regulatory mechanisms of axonal action potentials
2015 - 2018 Development of organic fiber electrodes for improving brain functions
2015 - 2018 ランビエ絞輪に局在するグルタミン酸受容体による活動電位伝播制御

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Papers (34)：

Wataru Matsunaga, Toru Shinoe, Moritoshi Hirono. GAD65 deficient mice are susceptible to ethanol-induced impairment of motor coordination and facilitation of cerebellar neuronal firing. PLOS ONE. 2023. 18. 5. e0286031-e0286031
Moritoshi Hirono, Masanori Nakata. Ghrelin signaling in the cerebellar cortex enhances GABAergic transmission onto Purkinje cells. Scientific Reports. 2023. 13. 1. 2150-2150
Moritoshi Hirono, Yuchio Yanagawa. Endocannabinoids regulate cerebellar GABAergic transmission in a synapse type-dependent manner. Journal of Neuroscience Research. 2021. 99. 3. 898-913
Yasushi Kishimoto, Moritoshi Hirono, Ryuichiro Atarashi, Suehiro Sakaguchi, Tohru Yoshioka, Shigeru Katamine, Yutaka Kirino. Impairment of cerebellar long-term depression and GABAergic transmission in prion protein deficient mice ectopically expressing PrPLP/Dpl. Scientific Reports. 2020. 10. 1
Hirono M, Watanabe S, Karube F, Fujiyama F, Kawahara S, Nagao S, Yanagawa Y, Misonou H. Perineuronal nets in the deep cerebellar nuclei regulate GABAergic transmission and delay eyeblink conditioning. The Journal of Neuroscience. 2018. 38. 27. 6130-6144

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MISC (21)：

Moritoshi Hirono, Fuyuki Karube, Yuchio Yanagawa. Modulatory Effects of Monoamines and Perineuronal Nets on Output of Cerebellar Purkinje Cells. Frontiers in Neural Circuits. 2021. 15. 661899
Moritoshi Hirono, Hiroaki Misonou. The roles of perineuronal nets in the deep cerebellar nuclei. Clinical Neuroscience. 2019. 37. 8. 1022-1023
Fumihito Saitow, Moritoshi Hirono, Hidenori Suzuki. Serotonin and synaptic transmission in the cerebellum. Handbook of the Cerebellum and Cerebellar Disorders. 2013. 915-926
廣野守俊. Diversity of interneurons elaborates cerebellar circuits. 生体の科学. 2011. 62. 4. 292-297
Chihiro Hisatsune, Hiroyuki Miyamoto, Moritoshi Hirono, Naohide Yamaguchi, Takeyuki Sugawara, Naoko Ogawa, Toshio Ohshima, Masahisa Yamada, Takao K. Hensch, Mitsuharu Hattori, et al. Disturbed Purkinje cell spike activity produces dystonia in mice lacking the type 1 inositol 1,4,5-trisphosphate receptor. NEUROSCIENCE RESEARCH. 2011. 71. E99-E99

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Books (6)：

Essentials of Cerebellum and Cerebellar Disorders
2023
Handbook of the Cerebellum and Cerebellar Disorders
2022
Cerebellum as a CNS Hub, H. Mizusawa, S. Kakei (eds.)
Springer Nature Switzerland AG 2021 2021
Essentials of Cerebellum and Cerebellar Disorders. A Primer For Graduate Students, D.L. Gruol et al. (eds.)
Springer International Publishing Switzerland 2016 2016
小脳-脳科学辞典
2015

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Professional career (1)：

Ph.D. (Waseda University)

Work history (4)：

2019/04 - 現在 Wakayama Medical University School of Medicine Department of Physiology Associate Professor
2015/04 - 2019/03 Doshisha University Organization for Research Initiatives and Development Research Associate Professor
2012/10 - 2015/03 Doshisha University Organization for Advanced Research and Education Research Associate Professor
2010/04 - 2012/09 RIKEN

Committee career (9)：

2023/04 - 現在日本薬理学会学術評議員
2022/09 - 現在 Associate Editor, Frontiers in Molecular Neuroscience
2020/05 - 現在 Review Editor, Frontiers in Molecular Neuroscience
2017/01 - 現在日本生理学会評議員
2011/08 - 現在活性アミンに関するワークショップ世話人

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Awards (1)：

2017/08 - 活性アミンに関するワークショップ功労賞

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