Rchr
J-GLOBAL ID：201201051987429566
Update date: Sep. 24, 2024
Kouji Nishi
ニシ コウジ | Kouji Nishi
Affiliation and department：
Research field (1)：
Clinical pharmacy
Research keywords (1)：
膵臓癌
Research theme for competitive and other funds (8)：
- 2020 - 2023 膵がん治療を目的としたアルブミン結合性NOラジカル放出型抗がん剤の開発
- 2018 - 2021 Development of poorly absorbable drug delivery system in vivo by sonodynamic action
- 2017 - 2020 Approach to developing of new pancreatic cancer therapeutic method focused on fatty acid metabolism
- 2019 - CD47修飾アルブミンキャリアーによる膵 がんターゲティングDDSの開発
- 2018 - 超音波の音響化学的作用による難吸収性薬物の生体内新規薬物送達システムの開発
- 2014 - 2016 Approach to new therapeutic strategy against pancreatic cancer by targeting lipid metabolism
- 2011 - 2014 Proteomic and metabolomic analysis on chemo-sensitivity and resistance of cancer towards personalized medicine
- 2011 - 2012 Approach to a new target for pancreatic cancer therapy to elevate the response of anti-cancer drugs
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Papers (69)：
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Koji Nishi, Yoshifumi Arimura, Naho Suetsugi, Takuro Beppu, Kaho Takasaki, Ayano Tamori, Ryo Kanda, Shuhei Imoto, Hirotaka Murase, Kenji Tsukigawa, et al. Ibuprofen-derived nitric oxide donors with a high affinity to human serum albumin induce cell death in pancreatic cancer cells through a non-caspase 3/7-mediated pathway. Biomedical reports. 2024. 21. 5. 159-159
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Koji Nishi, Ryo Kanda, Kaho Takasaki, Ayano Tamori, Yoshifumi Arimura, Shuhei Imoto, Hirotaka Murase, Kenji Tsukigawa, Masaki Otagiri, Keishi Yamasaki. Novel Diclofenac-NO Donor With High Affinity for Human Serum Albumin Induces Endoplasmic Reticulum Stress-mediated Cell Death in Human Pancreatic Cancer Cells. Anticancer research. 2024. 44. 9. 3793-3798
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Takashi Hasegawa, Kenji Tsukigawa, Kindness Commey, Mina Sakuragi, Shuhei Imoto, Kazuaki Taguchi, Koji Nishi, Masaki Otagiri, Keishi Yamasaki. Preparation and in Vitro Characterization of Fatty-Acid Modified Pirarubicin Nanosuspensions Stabilized by Albumin. Chemical & pharmaceutical bulletin. 2024. 72. 1. 21-27
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Kindness Lomotey Commey, Akari Nakatake, Airi Enaka, Ryota Nakamura, Koji Nishi, Kenji Tsukigawa, Hirohito Ikeda, Koki Yamaguchi, Daisuke Iohara, Fumitoshi Hirayama, et al. Study of the Structural Chemistry of the Inclusion Complexation of 4-Phenylbutyrate and Related Compounds with Cyclodextrins in Solution: Differences in Inclusion Mode with Cavity Size Dependency. International Journal of Molecular Sciences. 2023
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Kengo Yasuda, Hitoshi Maeda, Ryo Kinoshita, Yuki Minayoshi, Yuki Mizuta, Yuka Nakamura, Shuhei Imoto, Koji Nishi, Keishi Yamasaki, Mina Sakuragi, et al. Encapsulation of an Antioxidant in Redox-Sensitive Self-Assembled Albumin Nanoparticles for the Treatment of Hepatitis. ACS Nano. 2023
ｍore...
MISC (2)：
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Ono Tomomi, Nishi Koji, Fukunaga Naoko, Iwao Yasunori, Maruyama Toru, Otagiri Masaki. PEPTIDE MOIETIES OF HUMAN ALPHA1-ACID GLYCOPROTEIN ARE INVOLVED IN LIGAND-BINDING PROPERTIES. Abstracts of Annual meeting of Japanese Society for the Study of Xenobiotics. 2008. 23. 0. 162-162
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Ayaka Suenaga, Kazuaki Matsumoto, Koji Nishi, Mari Kikuchi, Daisuke Kadowaki, Masaki Otagiri, Yoshiko Tokutomi. alpha(1)-acid glycoprotein suppresses rat acute inflammatory paw edema through the inhibition of neutrophil activation and prostaglandin E-2 generation. DRUG METABOLISM REVIEWS. 2006. 38. 147-147
Education (3)：
- 2001 - 2004 Kumamoto University Graduate School, Division of Pharmaceutical Sciences
- 1999 - 2001 Kumamoto University Graduate School, Division of Pharmaceutical Sciences
- 1995 - 1999 Kumamoto University School of Pharmacy
Professional career (3)：
- 学士(薬学) (熊本大学)
- 修士(薬学) (熊本大学)
- 博士(薬学) (熊本大学)
Work history (7)：
Association Membership(s) (6)：
日本DDS学会
, 日本薬剤学会
, 日本癌学会
, アメリカ癌学会
, 日本薬物動態学会
, 日本薬学会
