Research field (1):
Environmental and pharmaceutical development resources
Research keywords (4):
伝統医学
, 放線菌
, 生合成
, 天然物化学
Research theme for competitive and other funds (6):
2020 - 2023 Verification of Southeast Asian traditional medicine
2017 - 2020 Evidence of medicinal properties and efficacy of Southeast Asian medicinal plants
2015 - 2019 Collection of new natural sources and analysis of their chemical constituents and construction of genetic resource bank
2014 - 2017 Biosynthetic studies on actinomycete metabolites for development of novel diabetes drugs
2012 - 2014 Biosynthetic study of manumycin antibiotics for creating novel analogs
2006 - 2009 Distribution Research of Malagasy and Kenyan medicinal plants and Development of Medical and Pharmaceutical Sources
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Papers (90):
Senda Kartika Rakainsa, Khoirun Nisa, Takuya Ito, Hiroyuki Morita. Antibacterial activity of five Indonesian medicinal plants and the isolation of compounds from Plectranthus scutellarioides. Journal of Applied Pharmaceutical Science. 2024. 14. 5. 185-192
Ryosuke Tanaya, Takeshi Kodama, Juthamart Maneenet, Yoko Yasuno, Atsushi Nakayama, Tetsuro Shinada, Hironobu Takahashi, Takuya Ito, Hiroyuki Morita, Suresh Awale, et al. Substrate-Dependent Alteration in the C- and O-Prenylation Specificities of Cannabis Prenyltransferase. Biological & pharmaceutical bulletin. 2024. 47. 2. 449-453
Yui Ito, Takuro Kobori, Yoko Urashima, Takuya Ito, Kikuko Hotta, Tokio Obata. Moesin affects the plasma membrane expression and the immune checkpoint function of CD47 in human ovarian clear cell carcinoma. Journal of reproductive immunology. 2023. 161. 104185-104185
Shuhei Fukuno, Katsuhito Nagai, Akemi Kurotobi, Yuki Sahori, Ryo Nakagawa, Rena Nomura, Takuya Ito, Hiroki Konishi. Danazol increases the oral bioavailability of midazolam by inactivation of hepatic and intestinal CYP3A in rats. Xenobiotica; the fate of foreign compounds in biological systems. 2023. 1-8
Structural analysis of a novel prenyltransferase
(量子ビームサイエンスフェスタ(Web) 2023)
Crystal structure analysis of novel enzyme derived from Streptomyces.
(KEK Progress Report (Web) 2023)
Involvement of Ezrin/Radixin/Moesin in the cell surface expression of immune checkpoint molecule PD-L1 in human endometrial carcinoma cell line
(日本薬学会年会要旨集(Web) 2023)
Ezrin modulates the cell surface localization of Programmed Death Ligand-1 in HEC-151 cells.
(日本薬学会年会要旨集(Web) 2023)
Ezrin contributes to the plasma membrane expression of Programmed Death Ligand-1 in A2780 cells
(日本薬学会年会要旨集(Web) 2023)