Research field (4)：
Biophysics
, Optical engineering and photonics
, Nanobioscience
, Nanomaterials
Research keywords (4)：
FRET
, 単一分子計測
, 統計的データ解析
, 光学顕微鏡
Research theme for competitive and other funds (4)：
2014 - 2017 Single-molecule FRET measurement of structural dynamics of intrinsically disordered domain in EGFR
2015 - 2016 生細胞深部の分子構造変化ダイナミクスをとらえる1分子FRET計測法の開発
2009 - 2010 Conformational dynamics measurement of EGFR by high-speed single-molecule FRET measurement
2006 - 2007 高圧力顕微鏡の開発と生体システムへの応用
Papers (45)：
Kenji Okamoto, Yasushi Sako. Two closed conformations of CRAF require the 14-3-3 binding motifs and cysteine-rich domain to be intact in live cells. Journal of Molecular Biology. 2023. 167989-167989
Yoshiko Nakagawa, Howard C.-H. Shen, Yusuke Komi, Shinju Sugiyama, Takaaki Kurinomaru, Yuri Tomabechi, Elena Krayukhina, Kenji Okamoto, Takeshi Yokoyama, Mikako Shirouzu, et al. Amyloid conformation-dependent disaggregation in a reconstituted yeast prion system. Nature Chemical Biology. 2022. 18. 3. 321-331
Wooseok Heo, Kazuto Hasegawa, Kenji Okamoto, Yasushi Sako, Kunihiko Ishii, Tahei Tahara. Scanning Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy: Conformational Dynamics of DNA Holliday Junction from Microsecond to Subsecond. The Journal of Physical Chemistry Letters. 2022. 1249-1257
