Rchr
J-GLOBAL ID：201201078583617046   Update date: Jun. 10, 2024

Kakuda Nobuto

カクダ ノブト | Kakuda Nobuto
Affiliation and department：
Doshisha University Faculty of Life and Medical Sciences

About Doshisha University Faculty of Life and Medical Sciences


Research field  (1)： Neuropathology
Research keywords  (6)： アミロイドβタンパク ,  γ-セクレターゼ ,  アルツハイマー病 ,  Amyloid beta protein ,  gamma-secretase ,  Alzheimer's disease
Research theme for competitive and other funds  (5)：
  • 2023 - 2026 動脈硬化症の連鎖的破綻によるアルツハイマー病の発症機序解明
  • 2017 - 2020 Detecting early-stage biomarker of multiple sclerosis using Imaging Mass Spectrometry
  • 2016 - 2019 Efficacy of TSPAN for gamma-secretase activity
  • 2015 - 2016 TSPAN6によるγ-secretase活性変化の機序解明
  • 2004 - 2004 アルツハイマー病におけるガンマセクレターゼの機能解析
Papers (21)：
  • Haruko Miyazaki, Saki Nishioka, Tomoyuki Yamanaka, Manabu Abe, Yukio Imamura, Tomohiro Miyasaka, Nobuto Kakuda, Toshitaka Oohashi, Tomomi Shimogori, Kazuhiro Yamakawa, et al. Generation and characterization of cerebellar granule neurons specific knockout mice of Golli-MBP. Transgenic research. 2024
  • Masaya Ikegawa, Nobuto Kakuda, Tomohiro Miyasaka, Yumiko Toyama, Takashi Nirasawa, Karolina Minta, Jörg Hanrieder. Mass spectrometry imaging in Alzheimer's disease. Brain connectivity. 2023
  • Rikuya Yoshimura, Tomohiro Miyasaka, Satoru Funamoto, Takashi Saito, Takaomi C Saido, Masaya Ikegawa, Nobuto Kakuda. The senile plaque: Morphological differences in APP knock-in mice brains by fixatives. Brain and behavior. 2023. e2953
  • Nobuto Kakuda, Mako Takami, Masayasu Okochi, Kensaku Kasuga, Yasuo Ihara, Takeshi Ikeuchi. Switched Aβ43 generation in familial Alzheimer’s disease with presenilin 1 mutation. Translational Psychiatry. 2021. 11. 1. 558-558
  • Ayaka Hagita, Satoko Wada-Kakuda, Mika Nobuhara, Nobuto Kakuda, Tomohiro Miyasaka. Quantitative fractionation of tissue microtubules with distinct biochemical properties reflecting their stability and lability. Biochemical and biophysical research communications. 2021. 560. 186-191
ｍore...
MISC (45)：
  • 角田 伸人. Aβの病的・生理的役割再考 孤発性・家族性ADにおけるAβ産生と老人斑の再考. Dementia Japan. 2023. 37. 4. 630-630
  • 角田 伸人, 吉村 陸哉, 宮坂 知宏, 船本 聡, 池川 雅哉, 斎藤 貴志, 西道 隆臣. ADモデルマウスにおける老人斑検出の最適化. Dementia Japan. 2023. 37. 4. 677-677
  • 大日方 藍, Liu Lixin, 原 範和, 長谷川 舞衣, 月江 珠緒, 五十嵐 一也, 幡野 敦, 角田 伸人, 菊地 正隆, 松本 雅記, et al. ヒト肝癌由来HepG2細胞株におけるAPOEの機能解析. Dementia Japan. 2023. 37. 4. 678-678
  • 外山友美子, 朴洪宣, 角田伸人, 韮澤崇, 村山繁雄, 貫名信行, 池川雅哉. イメージング質量分析法を用いたアルツハイマー病をはじめとする脳病理解析. 組織細胞化学. 2022. 2022
  • 外山友美子, 徳平壮一郎, 朴洪宣, 韮澤崇, 角田伸人, 宮坂知宏, 村山繁雄, 齊藤祐子, 内藤康秀, 貫名信行, et al. イメージング質量分析法を用いたアルツハイマー病脳の組織マルチオミクス解析. Dementia Japan. 2021. 35. 4
ｍore...
Patents (5)：
Education (8)：
  • - 2005 The University of Tokyo
  • - 2005 The University of Tokyo Graduate School, Division of Medical Sciences
  • - 2001 Tokyo Institute of Technology Bioscience and Biotechnology Biological Information
  • - 2001 Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering
  • - 1999 Tokyo Institute of Technology School of Bioscience and Biotechnology
Show all
Professional career (1)：
  • Master of Engineering (Tokyo Institute of Technology)
Work history (4)：
  • 2015/04 - 現在 Doshisha University Faculty of Life and Medical Sciences Department of Medical Life Systems
  • 2013/09 - 2015/03 KU Leuven Postdoctral fellow
  • 2011/04 - 2013/08 Doshisha University Organization for Research Initiatives and Development Researcher
  • 2005/04 - 2011/03 株式会社 免疫生物研究所
Association Membership(s) (1)：
日本認知症学会
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