Research theme for competitive and other funds (17):
2021 - 2024 A novel disease modification strategy for Parkinson disease by PGK enhancement
2021 - 2024 Targeting basal autophagy as therapeutic drugs in neurodegenerative diseases
2021 - 2024 Functional morphology of mice that can be visualized neuron-specific autophagy under stress
2020 - 2022 Comprehensive analysis of aggregate-resistant structure and its application for disease prevention
2018 - 2021 Pathogenesis of ALS linked p62-mutants from the point of view of autophagy and oxidative stress
2017 - 2021 Functional and morphological survey of the involvement of autophagy in stress and emotional system
2015 - 2019 A trial of avoiding disease propagation targeted on the synuclein aggregation and lysophagy
2015 - 2018 Identification of neurotoxic alpha-synuclein oligomers in Parkinson's disease and its application to molecular targeted therapy
2015 - 2018 Analysis of autophagic degradation of alpha-synuclein by p62-phosphorylation
2013 - 2018 Involvement of RNA editing of 5HT2C receptor in emotion and stress: functional and morphological study
2012 - 2016 Habitual alcohol-drinking behavior associated with active ghrelinergic and serotonergic neurons in the lateral hypothalamus and amygdala
2013 - 2015 For the in vivo imaging of 5-HT2C receptor activity using Tango system
2012 - 2015 The role of BAG3/HSP70 complex in selective autophagic degradation of alpha-synuclein
2011 - 2013 Elucidation of characters and neurotoxic mechanisms of alpha-synuclein oligomers and its application to molecular targeted therapy
2009 - 2011 Functional morphology of neuropeptide RLN3-survey for the involvement in emotion and food intake-
2008 - 2010 Exploration of intracellular protease property and control factors of neurosin with α-synuclein degrading activity
2006 - 2007 Functional and morphological analysis of a novel peptide relaxin 3 in the central nervous system
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Papers (65):
Ayumi Matsuki, Yoshihisa Watanabe, Sho Hashimoto, Atsushi Hoshino, Satoaki Matoba. Cathepsin L prevents the accumulation of alpha-synuclein fibrils in the cell. Genes to cells : devoted to molecular & cellular mechanisms. 2024
Yoshihisa Watanabe, Katsutoshi Taguchi, Masaki Tanaka. Roles of Stress Response in Autophagy Processes and Aging-Related Diseases. International journal of molecular sciences. 2023. 24. 18
Masaki Tanaka, Shunji Yamada, Yoshihisa Watanabe. The Role of Neuropeptide Y in the Nucleus Accumbens. International journal of molecular sciences. 2021. 22. 14