Rchr
J-GLOBAL ID：201201084500571295   Update date: Oct. 03, 2024

Hirota Kouji

ヒロタ コウジ | Hirota Kouji
Affiliation and department：
Tokyo Metropolitan University Graduate School of Science, Graduate School of Science

About Tokyo Metropolitan University Graduate School of Science, Graduate School of Science


Homepage URL  (1)： https://khirota9.wixsite.com/website
Research field  (3)： Genetics ,  Molecular biology ,  Cell biology
Research keywords  (30)： 組換え ,  ヒストン修飾 ,  DT40 ,  相同組換え ,  ノンコーディングRNA ,  Exo1 ,  DT40細胞 ,  Blm ,  組換え促進法 ,  細胞分化 ,  イムノグロブリン ,  トリBリンパ球 ,  標的組換え ,  クロマチン再編成 ,  transcriptome ,  クロマチン ,  染色体 ,  減数分裂 ,  転写制御 ,  DNA複製 ,  ストレス応答 ,  ヒストンアセチル化 ,  バイオテクノロジー ,  癌 ,  セントロメア ,  ゲノム ,  non-coding RNA ,  SPO11 ,  Bloom症候群 ,  姉妹染色体結合
Research theme for competitive and other funds  (21)：
  • 2023 - 2027 A novel non-invasive assessment of atherosclerotic risk using a combination of saliva exRNA measurement and a food model, and its application to the diet
  • 2022 - 2025 相同的組換えでの相同並行三重鎖DNAの働き
  • 2019 - 2024 International collaborations for revealing the synergistic genetic relationship in genome maintenance systems
  • 2021 - 2023 Search for a pioneer polymerase complex that opens chromatin in non-coding RNA transcribed regions
  • 2020 - 2023 Role of proofreading exonuclease activity of replicative polymerase epsilon in replication fork slowing at DNA damage
Show all
Papers (104)：
  • Hidetaka Seo, Kouji Hirota, Kunihiro Ohta. Molecular mechanisms of avian immunoglobulin gene diversification and prospect for industrial applications. Frontiers in immunology. 2024. 15. 1453833-1453833
  • Tasnim Ahmad, Ryotaro Kawasumi, Tomoya Taniguchi, Takuya Abe, Kazuhiro Terada, Masataka Tsuda, Naoto Shimizu, Toshiki Tsurimoto, Shunichi Takeda, Kouji Hirota. The proofreading exonuclease of leading-strand DNA polymerase epsilon prevents replication fork collapse at broken template strands. Nucleic Acids Research. 2023
  • Ivan Psakhye, Ryotaro Kawasumi, Takuya Abe, Kouji Hirota, Dana Branzei. PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesion. Nature structural & molecular biology. 2023
  • Mubasshir Washif, Tasnim Ahmad, Md Bayejid Hosen, Md Ratul Rahman, Tomoya Taniguchi, Hiromori Okubo, Kouji Hirota, Ryotaro Kawasumi. CTF18-RFC contributes to cellular tolerance against chain-terminating nucleoside analogs (CTNAs) in cooperation with proofreading exonuclease activity of DNA polymerase ε. DNA repair. 2023. 127. 103503-103503
  • Daiki Ikemoto, Tomoya Taniguchi, Kouji Hirota, Kiyoshi Nishikawa, Kan Okubo, Takuya Abe. Application of neural network-based image analysis to detect sister chromatid cohesion defects. Scientific Reports. 2023. 13. 1
ｍore...
MISC (20)：
ｍore...
Education (3)：
  • 1998 - 2001 The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry
  • 1996 - 1998 The University of Tokyo Graduate School of Science Department of Biophysics and Biochemistry
  • 1992 - 1996 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
Professional career (1)：
  • 博士(理学) (東京大学大学院理学系研究科生物化学専攻)
Work history (5)：
  • 2012/04 - 現在 Tokyo Metropolitan University Graduate School of Science, Graduate School of Science
  • 2010/05 - 2012/03 京都大学 医学(系)研究科(研究院) 准教授
  • 2008/04 - 2010/04 京都大学 医学(系)研究科(研究院) 助教
  • 2005/04 - 2008/03 理化学研究員 基礎科学特別研究員
  • 2001/04 - 2005/03 理化学研究所 協力研究員
Association Membership(s) (3)：
THE JAPANESE ENVIRONMENTAL MUTAGEN SOCIETY ,  THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM