Rchr
J-GLOBAL ID：201201084712183007   Update date: Sep. 19, 2024

Takahashi Hiroo

タカハシ ヒロオ | Takahashi Hiroo
Affiliation and department：
Kagawa University Medical Faculty

About Kagawa University Medical Faculty


Homepage URL  (1)： http://kaken.nii.ac.jp/ja/r/20390685
Research field  (2)： Neuroscience - general ,  Developmental biology
Research keywords  (26)： 包括脳ネットワーク ,  Pax6 ,  嗅細胞 ,  分化 ,  BMPシグナル ,  発生・分化 ,  領域特異性 ,  神経科学 ,  ノックインマウス ,  嗅覚系 ,  レンチウイルス ,  グアニル酸シクラーゼ ,  ニューロスフェア ,  炭酸脱水酵素 ,  CO2 ,  GFP ,  成体神経新生 ,  神経幹細胞 ,  再生医療 ,  樹状突起 ,  シングルセルマイクロアレイ ,  嗅球介在ニューロン ,  in vitro系 ,  嗅覚神経系 ,  5T4 ,  移植
Research theme for competitive and other funds  (20)：
  • 2022 - 2025 脳梗塞から脳を守る分子メカニズムの制御機構
  • 2022 - 2025 A novel therapeutic strategy for ischemic stroke based on understanding how subsequently induced Npas4 expression potentiates protecting neurons from death
  • 2019 - 2023 A novel therapeutic strategy for ischemic stroke based on reshaping neuronal circuits in an activity-dependent manner
  • 2019 - 2022 A novel therapeutic strategy for ischemic stroke based on the activity-dependent transcription factor Npas4
  • 2018 - 2021 神経活動依存的な転写因子Npas4が脳梗塞から脳を守るメカニズムの解明
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Papers (24)：
  • Daiki Ojima, Yoko Tominaga, Takashi Kubota, Atsushi Tada, Hiroo Takahashi, Yasushi Kishimoto, Takashi Tominaga, Tohru Yamamoto. Impaired Hippocampal Long-Term Potentiation and Memory Deficits upon Haploinsufficiency of MDGA1 Can Be Rescued by Acute Administration of d-Cycloserine. International Journal of Molecular Sciences. 2024
  • Keiko Honda, Hiroo Takahashi, Saori Hata, Ruriko Abe, Takashi Saito, Takaomi C Saido, Hidenori Taru, Yuriko Sobu, Kanae Ando, Tohru Yamamoto, et al. Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging. Scientific reports. 2024. 14. 1. 18471-18471
  • S M Khaledur Rahman, Zahir Hussain, Katsuya Morito, Naoko Takahashi, Mohammad Mamun Sikder, Tamotsu Tanaka, Ken-Ichi Ohta, Masaki Ueno, Hiroo Takahashi, Tohru Yamamoto, et al. Formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2ε in an ex vivo murine model of brain ischemia. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2022. 1867. 12. 159222-159222
  • Hiroo Takahashi, Tohru Yamamoto, Akio Tsuboi. Molecular mechanisms underlying activity-dependent ischemic tolerance in the brain. Neuroscience research. 2022
  • Yohei Kokudo, Takahiro Arakawa, Hiroo Takahashi, Hideki Kobara, Masaki Kamada, Kazushi Deguchi, Tetsuo Touge, Tsutomu Masaki, Tohru Yamamoto. Ascending spinal tract formation in chick embryo originating from different spinal regions. Brain research. 2021. 1768. 147595-147595
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MISC (31)：
  • 多田 篤史, 田之上 優, 黒川 直弘, 津島 希海, 尾嶋 大喜, Hossain MD Razib, 小坂 信二, 芳地 一, 窪田 剛志, 高橋 弘雄, et al. シナプス形成抑制因子MDGA1の欠失による精神神経疾患様行動異常と、これを抑止する薬剤の探索. 日本薬学会年会要旨集. 2020. 140年会. 28P-am125
  • Hiroo Takahashi, Sei-ichi Yoshihara, Yoichi Ogawa, Ryo Asahina, Tatsuro Kitano, Akio Tsuboi. A specific subtype of olfactory bulb interneurons is necessary for odor detection and odor-background segregation. CHEMICAL SENSES. 2016. 41. 9. E148-E148
  • Sei-ichi Yoshihara, Hiroo Takahashi, Akio Tsuboi. Molecular Mechanisms Regulating the Dendritic Development of Newborn Olfactory Bulb Interneurons in a Sensory Experience-Dependent Manner. FRONTIERS IN NEUROSCIENCE. 2016. 9
  • 高橋 弘雄, 坪井 昭夫. 嗅覚系におけるCO2センシングの分子機構 (特集 バイオセンサ). におい・かおり環境学会誌. 2015. 46. 3. 209-217
  • Hiroo Takahashi, Sei-Ichi Yoshihara, Ryo Asahina, Yoshiki Tamada, Akio Tsuboi. Characterization of newborn interneurons in the mouse olfactory bulb using postnatal electroporation. Electroporation Methods in Neuroscience. 2015. 93-103
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Education (1)：
  • 2000 - 2003 The Graduate University for Advanced Studies School of Life Science Department of Basic Biology
Professional career (1)：
  • Ph.D. (The Graduate University for Advanced Studies)
Work history (6)：
  • 2022/01 - 現在 Kagawa University Faculty of Medicine
  • 2018/10 - 2021/12 Kagawa University Faculty of Medicine
  • 2017/03 - 2018/09 Nara Medical University
  • 2006/10 - 2017/02 Nara Medical University
  • 2003/10 - 2006/09 National Institute for Basic Biology
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Association Membership(s) (3)：
THE JAPANESE ASSOCIATION FOR THE STUDY OF TASTE AND SMELL ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPANESE SOCIETY OF NEUROLOGY
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