Tamura Tomohiko

タムラトモヒコ | Tamura Tomohiko

Affiliation and department：
Other affiliations (2)：

Homepage URL (1)： http://www-user.yokohama-cu.ac.jp/~immunol/

Research field (2)： Hematology and oncology , Immunology

Research keywords (12)： Monocytes/macrophages , Dendritic cells , Immune responses , Cell proliferation , Epigenome , Differentiation , Transcription factors , 免疫制御学 , 血液免疫学 , 造血幹細胞移植学 , 血液内科学 , サイトカイン

Research theme for competitive and other funds (30)：

2023 - 2025 転写因子・液-液相分離依存性クロマチンドメインによる免疫細胞分化制御
2022 - 2025 膵癌における腫瘍関連マクロファージのマスター転写因子を標的とした新規治療法への探索研究(代表)
2021 - 2024 Single-Cell RNA sequenceによるARDS病態の網羅的探索
2021 - 2024 インターフェロン制御因子5を標的とした急性呼吸窮迫症候群の分子標的治療の開発
2021 - 2024 Higher-order chromatin structure dynamics during dendritic cell development in vivo

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Papers (145)：

Mayoko Tsuji, Mitsuko Kondo, Akira Nishiyama, Tomohiko Tamura, Ayako Nakamura-Ishizu, Miho Koizumi, Hiroaki Honda, Etsuko Tagaya. STING/RANTES pathway in airway epithelium enhances Der p1-induced airway inflammation. Allergy. 2024. 79. 7. 2008-2011
Ayaka Iwata, Juri Maruyama, Shibata Natsuki, Akira Nishiyama, Tomohiko Tamura, Minoru Tanaka, Shigeyuki Shichino, Takao Seki, Toshihiko Komai, Tomohisa Okamura, et al. Egr2 drives the differentiation of Ly6Chi monocytes into fibrosis-promoting macrophages in metabolic dysfunction-associated steatohepatitis in mice. Communications biology. 2024. 7. 1. 681-681
Takaya Yamasaki, Akira Nishiyama, Nagomi Kurogi, Koutarou Nishimura, Shion Nishida, Daisuke Kurotaki, Tatsuma Ban, Jordan A. Ramilowski, Keiko Ozato, Atsushi Toyoda, et al. Physical and functional interaction among Irf8 enhancers during dendritic cell differentiation. Cell Reports. 2024. 43. 4. 114107-114107
Kenji Kubara, Kazuto Yamazaki, Takayuki Miyazaki, Keita Kondo, Daisuke Kurotaki, Tomohiko Tamura, Yuta Suzuki. Lymph node macrophages drive innate immune responses to enhance the anti-tumor efficacy of mRNA vaccines. Molecular therapy : the journal of the American Society of Gene Therapy. 2024
Shunichiro Tsukamoto, Toru Suzuki, Hiromichi Wakui, Tatsuki Uehara, Juri Ichikawa, Hiroshi Okuda, Kotaro Haruhara, Kengo Azushima, Eriko Abe, Shohei Tanaka, et al. Angiotensin II type 1 receptor-associated protein in immune cells: a possible key factor in the pathogenesis of visceral obesity. Metabolism: clinical and experimental. 2023. 149. 155706-155706

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MISC (51)：

藩龍馬, 佐藤豪, 菊地雅子, 菊地雅子, 西村謙一, 吉見竜介, 桐野洋平, 松本佳子, 日原裕恵, 伊藤昌史, et al. 全身性エリテマトーデスにおける転写因子IRF5の阻害は現行治療法の限界を克服した新規治療法となる可能性がある. 日本インターフェロン・サイトカイン学会学術集会抄録集. 2021. 85th (CD-ROM)
佐藤豪, 藩龍馬, 菊地雅子, 菊地雅子, 真鍋昭雄, 田形典子, 西村謙一, 吉見竜介, 桐野洋平, 松本佳子, et al. 転写因子IRF5を標的とした全身性エリテマトーデスの新規治療法開発. 日本インターフェロン・サイトカイン学会学術集会抄録集. 2019. 84th
川瀬航, 黒滝大翼, 鈴木裕太, 石原比呂之, 藩龍馬, 佐藤豪, 柳井秀元, 谷口維紹, 塚原克平, 田村智彦. IRF5siRNA含有生分解性脂質ナノ粒子はコンカナバリンA誘導性肝障害を改善する. 日本インターフェロン・サイトカイン学会学術集会抄録集. 2019. 84th
Tomohiko Tamura, Daisuke Kurotaki. [Progress in single-cell analysis of hematopoiesis]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2019. 60. 9. 1075-1083
Koichi Murakami, Daisuke Kurotaki, Wataru Kawase, Shunsuke Soma, Yumi Fukuchi, Hiroyoshi Kunimoto, Ryusuke Yoshimi, Shuhei Koide, Motohiko Oshima, Takako Hishiki, et al. Regulation of Mitophagy By O-Linked N-Acetylglucosamine Transferase Is Essential for Hematopoietic Stem Cell Maintenance. BLOOD. 2018. 132

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Education (2)：

1991 - 1995 Yokohama City University Graduate Graduate School of Medicine
1984 - 1990 Yokohama City University

Professional career (1)：

博士(医学) (横浜市立大学)

Work history (14)：

2018/10 - 現在 Yokohama City University Advanced Medical Research Center
2012/09 - 現在 Yokohama City University Advanced Medical Research Center
2009/09 - 現在 Yokohama City University Graduate School of Medicine, Graduate
2018/04 - 2023/03 Yokohama City University Graduate School of Medicine, Graduate
2007/07 - 2009/08 The University of Tokyo Graduate School of Medicine

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Association Membership(s) (7)：

INTERNATIONAL CYTOKINE & INTERFERON SOCIETY , THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS , THE AMERICAN SOCIETY OF HEMATOLOGY , THE JAPANESE CANCER ASSOCIATION , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , JAPANESE SOCIETY FOR IMMUNOLOGY , THE JAPANESE SOCIETY OF HEMATOLOGY

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