Rchr
J-GLOBAL ID:201201096798723090   Update date: Jun. 19, 2024

Tsuiji Hitomi

Tsuiji Hitomi
Affiliation and department:
Job title: Professor
Homepage URL  (1): https://sites.google.com/view/agusougou?usp=sharing
Research field  (3): Neuroscience - general ,  Molecular biology ,  Other
Research keywords  (6): 薬学教育 ,  筋萎縮性側索硬化症 ,  認知症 ,  スプライシング ,  ノンコーディングRNA ,  RNA疾患
Research theme for competitive and other funds  (5):
  • 2020 - 2024 RNA結合タンパク質量の増減による、筋萎縮性側索硬化症ALSの治療法開発
  • 2017 - 2020 Elucidation of pathophysiological implications of interneuron degeneration in frontotemporal dementia
  • 2013 - 2017 Common defects of RNA metabolism in motor neuron diseases SMA and ALS
  • 2011 - 2012 Defective RNA metabolism in motor neurons from Amyotrophic Lateral Scelosis patients
  • 2007 - 2008 Functional analysis of Gomafu, the mRNA-like non-coding RNA
Papers (23):
  • Antonios Apostolopoulos, Naohiro Kawamoto, Siu Yu A Chow, Hitomi Tsuiji, Yoshiho Ikeuchi, Yuichi Shichino, Shintaro Iwasaki. dCas13-mediated translational repression for accurate gene silencing in mammalian cells. Nature communications. 2024. 15. 1. 2205-2205
  • Shintaro Oya, Katsunari Korogi, Takao Kohno, Hitomi Tsuiji, Dmytro I Danylchuk, Andrey S Klymchenko, Yosuke Niko, Mitsuharu Hattori. The Plasma Membrane Polarity Is Higher in the Neuronal Growth Cone than in the Cell Body of Hippocampal and Cerebellar Granule Neurons. Biological & pharmaceutical bulletin. 2023. 46. 12. 1820-1825
  • Yuma Kato, Minnie Naganuma, Ikuma Nakagawa, Kazunari Onodera, Hideyuki Okano, Haruhisa Inoue, Mitsuharu Hattori, Yohei Okada, Hitomi Tsuiji. C9ORF72 dipeptide repeat proteins disrupt formation of GEM bodies and induce aberrant accumulation of survival of motor neuron protein. bioRxiv. 2021
  • Hiroto Inagaki, Nao Hosoda, Hitomi Tsuiji, Shin-ichi Hoshino. Direct evidence that Ataxin-2 is a translational activator mediating cytoplasmic polyadenylation. Journal of Biological Chemistry. 2020. 295. 47. 15810-15825
  • Eisuke Okugawa, Himari Ogino, Tomofumi Shigenobu, Yuko Yamakage, Hitomi Tsuiji, Hisashi Oishi, Takao Kohno, Mitsuharu Hattori. Physiological significance of proteolytic processing of Reelin revealed by cleavage-resistant Reelin knock-in mice. Scientific reports. 2020. 10. 1. 4471-4471
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MISC (8):
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Education (3):
  • 1994 - 1999 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • 1992 - 1994 The University of Tokyo Faculty of Pharmaceutical Sciences
  • 1990 - 1992 東京大学 理科II類
Professional career (1):
  • Ph.D (University of Tokyo)
Work history (9):
  • 2022/09 - 現在 Aichi Gakuin University Graduate School of Pharmacy, Studies of Pharmacy
  • 2022/04 - 現在 Nagoya City University Graduate School of Pharmaceutical Sciences Visiting Professor
  • 2022/04 - 現在 Aichi Gakuin University School of Pharmacy, Department of Pharmaceutical Health Care and Science Professor
  • 2014/04 - 2022/03 Nagoya City University Graduate School of Pharmaceutical Sciences
  • 2014 - 2015 Nagoya University
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Committee career (3):
  • 2023/04 - 現在 Japan Neuroscience Society Councilor
  • 2023/04 - 現在 日本薬学会 代議員
  • 2018/04 - 2022/03 日本RNA学会 会計幹事
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