Nagae Masamichi

ナガエマサミチ | Nagae Masamichi

Affiliation and department：
Job title：助教

Research field (1)： Structural biochemistry

Research keywords (2)：包括脳ネットワーク , Structural Biology

Research theme for competitive and other funds (13)：

2022 - 2027 Identification of self-derived molecules recognized by immune sensors
2021 - 2025 免疫細胞レクチンシグレックの新規リガンド結合部位の証明と新しい免疫制御機構の解明
2020 - 2023 Structural studies on the variety and universality of GlcNAc transferases
2017 - 2020 Structural studies on meta-stable conformations of bisected glycan
2015 - 2017 Structural studies on the pathological mechanism of dystroglycanopathy

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Papers (71)：

Ryosuke Takasaki, Emi Ito, Masamichi Nagae, Yuki Takahashi, Takuro Matsuoka, Wakana Yasue, Norihito Arichi, Hiroaki Ohno, Sho Yamasaki, Shinsuke Inuki. Development of Ribityllumazine Analogue as Mucosal-Associated Invariant T Cell Ligands. Journal of the American Chemical Society. 2024
Naoko Osada, Masamichi Nagae, Takahiro Yamasaki, Anne Harduin-Lepers, Yasuhiko Kizuka. Regulation of human GnT-IV family activity by the lectin domain. Carbohydrate research. 2024. 545. 109285-109285
Yuta Hashimoto, Haruka Kawade, WanXue Bao, Sayaka Morii, Miyako Nakano, Masamichi Nagae, Reiko Murakami, Yuko Tokoro, Misaki Nakashima, Zixuan Cai, et al. The K346T mutant of GnT-III bearing weak in vitro and potent intracellular activity. Biochimica et biophysica acta. General subjects. 2024. 1868. 9. 130663-130663
Yuko Tokoro, Masamichi Nagae, Miyako Nakano, Anne Harduin-Lepers, Yasuhiko Kizuka. LacdiNAc synthase B4GALNT3 has a unique PA14 domain and suppresses N-glycan capping. The Journal of biological chemistry. 2024. 300. 7. 107450-107450
Seita Tomida, Masamichi Nagae, Yasuhiko Kizuka. Corrigendum to "Distinctive domains and activity regulation of core fucosylation enzyme FUT8" [BBA General Subjects 1868 (2024)/130561]. Biochimica et biophysica acta. General subjects. 2024. 1868. 6. 130615-130615

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MISC (60)：

長田菜緒子, 長江雅倫, 中の三弥子, Mishra Sushil K., Doerksen Robert J., 舘野浩章, 木塚康彦. 糖転移酵素GnT-IVファミリーが持つユニークなレクチンドメインの役割. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-030]
長田菜緒子, 長江雅倫, 長江雅倫, 中の三弥子, MISHRA Sushil K., DOERKSEN Robert J., 木塚康彦, 木塚康彦. Recognition of self N-glycan by lectin domain of GnT-IV glycosyltransferase. 日本糖質学会年会要旨集. 2023. 42nd
橋本雄太, 川出遥加, 森井爽, 中の三弥子, 長江雅倫, 長江雅倫, 木塚康彦, 木塚康彦. Analysis of the regulatory mechanisms of intracellular activity of GnT-III K346T mutant. 日本糖質学会年会要旨集. 2023. 42nd
富田晟太, 長江雅倫, 木塚康彦, 木塚康彦. Analysis of regulation mechanisms of activity of fucosyltransferase FUT8. 日本糖質学会年会要旨集. 2023. 42nd
長田菜緒子, 長江雅倫, 木塚康彦. 糖転移酵素GnT-IVa,-IVbの糖タンパク質基質に対する選択性の研究. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 3T02a-06

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Lectures and oral presentations (58)：

A transient metabolite in Mycobacterium leprae PGL-I biosynthesis pathway is a potent PAMP
(U.S.-Japan Cooperative Medical Sciences Program 2023)
Structural studies of public TCR against SARS-CoV-2 peptide clarified the broad spectrum of the clonotype
(2022)
Self-antigen for mucosal-associated invariant T (MAIT) cell
(2022)
Self-antigen for mucosal-associated invariant T (MAIT) cells
(The 1st International School on Advanced Immunology 2022)
レクチン受容体による結晶性物質の認識機構に関する構造基盤の解明
(第41回日本糖質学会年会 2022)

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Education (3)：

2001 - 2004 Yokohama City University Graduate
1999 - 2001 Kyoto University Graduate School of Science
1995 - 1999 Kyoto University, Faculty of Science

Professional career (1)：

博士(理学) (横浜市立大学)

Work history (8)：

2020/04 - 現在 (兼任)大阪国際がんセンター
2020/01 - 現在 Osaka University Research Institute for Microbial Diseases
2019/04 - 現在 (兼任)名古屋大学大学院医学研究科非常勤講師
2016/10 - 2020/01 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Chemistry
2013/04 - 2016/10 (兼任)東京医科歯科大学大学院医歯学総合研究科非常勤講師

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Awards (2)：

2014/11 - 東京糖鎖研究会(GlycoTokyo) 奨励賞
2011/06 - PSSJ Young Scientist Award

Association Membership(s) (5)：

THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH , THE BIOPHYSICAL SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN , PROTEIN SCIENCE SOCIETY OF JAPAN

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