2020 - 2023 Structural studies on the variety and universality of GlcNAc transferases
2017 - 2020 Structural studies on meta-stable conformations of bisected glycan
2015 - 2017 Structural studies on the pathological mechanism of dystroglycanopathy
2013 - 2017 Structural analysis of asymmetrically branched glycans
2014 - 2016 髄液内におけるN-GlcNAc型糖鎖生成機構の解明
2013 - 2015 脂質修飾蛋白質の輸送に関わるp24蛋白質複合体の構造基盤の解明
2012 - 2014 Structural basis for C-type lectin receptor in innate immunity
2012 - 2014 PSTによる神経細胞因子NCAMのポリシアル化機構の解明
2013 - 2014 脳型トランスフェリンの機能構造解析
2013 - 脂質修飾タンパク質輸送装置の構造生物学的研究
2012 - 2013 Development of a novel carbohydrate-detection probe based on 3D structural information
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Papers (65):
Seita Tomida, Masamichi Nagae, Yasuhiko Kizuka. Distinctive domains and activity regulation of core fucosylation enzyme FUT8. Biochimica et biophysica acta. General subjects. 2024. 1868. 4. 130561-130561
Shotaro Mori, Masamichi Nagae, Sho Yamasaki. Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. International Immunology. 2024
Emi Ito, Shinsuke Inuki, Yoshihiro Izumi, Masatomo Takahashi, Yuki Dambayashi, Lisa Ciacchi, Wael Awad, Ami Takeyama, Kensuke Shibata, Shotaro Mori, et al. Sulfated bile acid is a host-derived ligand for MAIT cells. Science immunology. 2024. 9. 91. eade6924
Reina F Osuka, Masamichi Nagae, Akito Ohuchi, Shiho Ohno, Yoshiki Yamaguchi, Yasuhiko Kizuka. The cancer-associated glycosyltransferase GnT-V (MGAT5) recognizes the N-glycan core via residues outside its catalytic pocket. FEBS letters. 2023. 597. 24. 3102-3113
Shigenari Ishizuka, J Hessel M van Dijk, Tomomi Kawakita, Yuji Miyamoto, Yumi Maeda, Masamichi Goto, Guillaume Le Calvez, L Melanie Groot, Martin D Witte, Adriaan J Minnaard, et al. PGL-III, a Rare Intermediate of Mycobacterium leprae Phenolic Glycolipid Biosynthesis, Is a Potent Mincle Ligand. ACS central science. 2023. 9. 7. 1388-1399
長田菜緒子, 長江雅倫, 長江雅倫, 中の三弥子, MISHRA Sushil K., DOERKSEN Robert J., 木塚康彦, 木塚康彦. Recognition of self N-glycan by lectin domain of GnT-IV glycosyltransferase. 日本糖質学会年会要旨集. 2023. 42nd
橋本雄太, 川出遥加, 森井爽, 中の三弥子, 長江雅倫, 長江雅倫, 木塚康彦, 木塚康彦. Analysis of the regulatory mechanisms of intracellular activity of GnT-III K346T mutant. 日本糖質学会年会要旨集. 2023. 42nd
富田晟太, 長江雅倫, 木塚康彦, 木塚康彦. Analysis of regulation mechanisms of activity of fucosyltransferase FUT8. 日本糖質学会年会要旨集. 2023. 42nd
1999 - 2001 Kyoto University Graduate School of Science
1995 - 1999 Kyoto University, Faculty of Science
Professional career (1):
博士(理学) (横浜市立大学)
Work history (8):
2020/04 - 現在 (兼任)大阪国際がんセンター
2020/01 - 現在 Osaka University Research Institute for Microbial Diseases
2019/04 - 現在 (兼任)名古屋大学大学院医学研究科 非常勤講師
2016/10 - 2020/01 The University of Tokyo Graduate School of Pharmaceutical Sciences Department of Pharmaceutical Chemistry
2013/04 - 2016/10 (兼任)東京医科歯科大学大学院 医歯学総合研究科 非常勤講師
2011/07 - 2016/10 RIKEN
2007/04 - 2011/06 Osaka University Institute for Protein Research
2004/04 - 2007/03 High Energy Accelerator Research Organization
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Awards (2):
2014/11 - 東京糖鎖研究会(GlycoTokyo) 奨励賞
2011/06 - PSSJ Young Scientist Award
Association Membership(s) (5):
THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH
, THE BIOPHYSICAL SOCIETY OF JAPAN
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN
, PROTEIN SCIENCE SOCIETY OF JAPAN