Research field (2)：
Pharmacology
, Neuroscience - general
Research theme for competitive and other funds (16)：
2024 - 2027 ストレス抵抗性と抗うつ薬慢性作用に共通する神経機構の解明とその創薬展開
2021 - 2024 臓器感覚入力系におけるモノアミン神経細胞の情動表現解析
2020 - 2024 うつ病態発症・治療の決定因子の同定
2019 - 2024 負の情動下の意思決定行動変容の神経基盤:拡張扁桃体-大脳基底核回路の探求
2020 - 2023 Drug target finding based on the analysis of real world data
2018 - 2023 International collaboration for the study of drug action based on real-world clinical data
2020 - 2022 低分子から中分子に至るあらゆる化学構造のヒト作用予測モデルの開発
2019 - 2022 霊長類セロトニン系の光操作による心と体の相互関係のメカニズムの解明
2018 - 2021 The role of serotonin projection under negative emotions.
2018 - 2020 Identification of antidepressive serotonin projection as a possible target of cell transplantation therapy
2017 - 2019 Oligodendrocyte
2016 - 2019 Identification and pharmacological control of serotonergic projection involved in decision making
2016 - 2018 Genetic tools for circuit-based drug discovery
2014 - 2017 A research on the effects of miRNAs on serotonergic neuronal functions
2014 - 2015 Studies on mental disorder using patient-specific iPS cells
2012 - 2013 抗うつ薬の作用機構におけるグルタミン酸受容体の役割の解明
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Papers (116)：
Hikari Hatakama, Nozomi Asaoka, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko. Amelioration of obsessive-compulsive disorder by intracellular acidification of cortical neurons with a proton pump inhibitor. Translational psychiatry. 2024. 14. 1. 27-27
Yuto Fukui, Hisashi Shirakawa, Shuji Kaneko, Kazuki Nagayasu. Wild-Type DCTN1 Suppresses the Aggregation of DCTN1 Mutants Associated with Perry Disease. Biological & pharmaceutical bulletin. 2024. 47. 1. 253-258
Kazuki Nagayasu. Integrative Research of Neuropharmacology and Informatics Pharmacology for Mental Disorder. Biological & pharmaceutical bulletin. 2024. 47. 3. 556-561
HaiXiang Ma, LeYuan Gu, YuLing Wang, Qing Xu, Yuanli Zhang, WeiHui Shao, Qian Yu, XiTing Lian, Lu Liu, JiaXuan Gu, et al. The States of Different 5-HT Receptors Located in the Dorsal Raphe Nucleus Are Crucial for Regulating the Awakening During General Anesthesia. Molecular neurobiology. 2023. 60. 12. 6931-6948
Masashi Kakae, Hiroki Nakajima, Shota Tobori, Ayaka Kawashita, Jun Miyanohara, Misa Morishima, Kazuki Nagayasu, Takayuki Nakagawa, Eiji Shigetomi, Schuichi Koizumi, et al. The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production. Science advances. 2023. 9. 29. eadh0102
Osaka University School of Pharmaceutical Sciences
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Awards (4)：
2024/03 - 日本薬理学会 学術奨励賞
2023/03 - 日本薬学会 日本薬学会奨励賞
2019/08 - 生体機能と創薬シンポジウム 優秀発表賞
2016/01 - 日本薬学会 近畿支部奨励賞
Association Membership(s) (5)：
北米神経科学会
, THE JAPAN NEUROSCIENCE SOCIETY
, THE PHARMACEUTICAL SOCIETY OF JAPAN
, THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY
, THE JAPANESE PHARMACOLOGICAL SOCIETY
