Rchr
J-GLOBAL ID：201301007949375647   Update date: Nov. 02, 2024

Hidehito Tochio

トチオ ヒデヒト | Hidehito Tochio
Affiliation and department：
Kyoto University

About Kyoto University


Research field  (4)： Structural biochemistry ,  Immunology ,  Biophysics ,  Molecular biochemistry
Research keywords  (6)： NMR ,  Structural Biology ,  Innate Immunity ,  in-cell NMR ,  Ubiquitin chain ,  MyD88
Research theme for competitive and other funds  (23)：
  • 2016 - 2019 Structural biology of inflammatory response
  • 2014 - 2019 Development of analyzing methods for protein-protein interactions and protein dynamics by means of ODMR and in-cell NMR
  • 2016 - 2017 Diamond NVC for protein analysis
  • 2012 - 2016 Structural probing of RNA molecules with in-cell NMR
  • 2015 - 2016 直鎖型ポリユビキチン鎖合成の構造的基盤の解明
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Papers (114)：
  • Kazuki Kasai, Kayo Imamura, Masatoshi Uno, Naotaka Sekiyama, Tomoko Miyata, Fumiaki Makino, Ryusei Yamada, Yoshiki Takahashi, Noriyuki Kodera, Keiichi Namba, et al. From Monomers to Oligomers: Structural Mechanism of Receptor-Triggered MyD88 Assembly in Innate Immune Signaling. 2024
  • Kayo Imamura, Ken-Ichi Akagi, Yohei Miyanoiri, Hirokazu Tsujimoto, Takatsugu Hirokawa, Hideo Ashida, Kaori Murakami, Asuka Inoue, Ryoji Suno, Takahisa Ikegami, et al. Interaction modes of human orexin 2 receptor with selective and nonselective antagonists studied by NMR spectroscopy. Structure. 2024
  • Naotaka Sekiyama, Kiyofumi Takaba, Saori Maki-Yonekura, Ken-ichi Akagi, Yasuko Ohtani, Kayo Imamura, Tsuyoshi Terakawa, Keitaro Yamashita, Daigo Inaoka, Koji Yonekura, et al. ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures. Proceedings of the National Academy of Sciences. 2022. 119. 38
  • Xue-Ni Hou, Hidehito Tochio. Characterizing conformational ensembles of multi-domain proteins using anisotropic paramagnetic NMR restraints. Biophysical Reviews. 2022. 14. 1. 55-66
  • Xue-Ni Hou, Naotaka Sekiyama, Yasuko Ohtani, Feng Yang, Yohei Miyanoiri, Ken-ichi Akagi, Xun-Cheng Su, Hidehito Tochio. Conformational Space Sampled by Domain Reorientation of Linear Diubiquitin Reflected in Its Binding Mode for Target Proteins. ChemPhysChem. 2021. 22. 14. 1505-1517
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MISC (73)：
  • 徳永暉, 藤田宏明, WALINDA Erik, 大木出, 有吉眞理子, 杤尾豪人, 岩井一宏, 白川昌宏. 直鎖型ユビキチンリガーゼLUBACの安定化機構の構造基盤研究. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st
  • 白川昌宏, 五十嵐龍治, 源城拓哉, 外間進悟, 藤咲貴大, 寺田大紀, 田辺竜太郎, 大木出, 吉成洋祐, 杤尾豪人. ダイヤモンドNV中心(NVC)による量子センシングによる細胞内の物性測定. 日本分子生物学会年会プログラム・要旨集(Web). 2018. 41st
  • 宇野雅俊, 中山隆宏, 紺野宏記, 大西秀典, 白川昌宏, 杤尾豪人. 免疫シグナルハブタンパク質MyD88の分子内相互作用解析. 日本生化学会大会(Web). 2017. 90th. ROMBUNNO.1P-0122 (WEB ONLY)-0122]
  • 白川昌宏, 五十嵐龍治, 五十嵐龍治, 源城拓哉, 外間進悟, 藤咲貴大, 寺田大紀, 田辺竜太郎, 大木出, 吉成洋祐, et al. 光検出磁気共鳴法による生細胞における1分子運動の計測. Abstracts. Annual Meeting of the NMR Society of Japan. 2017. 56th
  • Tochio Hidehito. NMR analysis of proteins in the cells. Chemistry. 2016. 71. 7. 64-65
ｍore...
Patents (5)：
Education (3)：
  • 1994 - 1998 大阪大学大学院 理学研究科博士課程 生物科学専攻
  • 1992 - 1994 大阪大学大学院 理学研究科修士課程 有機化学専攻
  • 1988 - 1992 Osaka University
Professional career (1)：
  • 理学博士 (大阪大学)
Work history (4)：
  • 2014/07 - 現在 Kyoto University Graduate School of Science Professor
  • 2008/03 - 2014/06 Kyoto University Graduate School of Engineering Associate Professor
  • 2001/04 - 2008/03 Yokohama City University Assistant Professor
  • 1998/04 - 2001/03 The Hong Kong University of Science & Technology Depart of Biochemistry Research Associate
Association Membership(s) (3)：
THE BIOPHYSICAL SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  The Nuclear Magnetic Resonance Society of Japan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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