Rchr
J-GLOBAL ID:201301012677721447
Update date: Jun. 19, 2024
Tsumoto Kunichika
ツモト クニチカ | Tsumoto Kunichika
Affiliation and department:
Job title:
准教授
Research field (1):
Physiology
Research keywords (9):
Bifurcation Phenomena
, Cardiomyocyte
, electrophysiology
, arrhythmia
, nonlinear dynamical system
, numerical computation
, mathematical modeling
, excitation propagation
, circadian rhythm
Research theme for competitive and other funds (10):
- 2024 - 2027 撃発活動によって惹起された頻脈性心室不整脈の持続機構の解明
- 2022 - 2025 分岐解析によるヒト心筋細胞モデルデータベース構築と心臓自動能発生機序の統合的解明
- 2021 - 2024 Mechanisms of triggered activity in lethal arrhythmias: in silico study
- 2019 - 2022 Theoretical and experimental study of controlling cardiac cell system dynamics using HL-1 mouse cardiomyocytes and a mathematical model
- 2017 - 2020 Mathematical analysis of arrhythmogenesis for bradycardia
- 2016 - 2019 The elucidation of mechanisms underlying triggered activity in inheritable lethal arrhythmias: in silico predictions
- 2010 - 2016 Research and development of a software platform for integrative multi-level systems biology
- 2012 - 2015 Roles of subcellular sodium channel redistribution in the generation of lethal arrhythmia: in silico study
- 2012 - 2015 Investigating mechanisms of ventricular arrhythmias induced in the Purkinje fiber network using computer simulation
- 2003 - 2004 遅延・断続特性を有する神経回路網の解析とその生体リズムへの応用に関する研究
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Papers (33):
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Kunichika Tsumoto, Takao Shimamoto, Yuma Aoji, Yukiko Himeno, Yu-hichi Kuda, Mamoru Tanida, Akira Amano, Yasutaka Kurata. Theoretical prediction of early afterdepolarization-evoked triggered activity formation initiating ventricular reentrant arrhythmias. Computer Methods and Programs in Biomedicine. 2023. 240. 107722-107722
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Kunichika Tsumoto, Yasutaka Kurata. Bifurcations and Proarrhythmic Behaviors in Cardiac Electrical Excitations. Biomolecules. 2022. 12. 3. 459-459
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Kunichika Tsumoto, Takashi Ashihara, Narumi Naito, Takao Shimamoto, Akira Amano, Yasutaka Kurata, Yoshihisa Kurachi. Specific decreasing of Na+ channel expression on the lateral membrane of cardiomyocytes causes fatal arrhythmias in Brugada syndrome. Scientific Reports. 2020. 10. 1
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津元国親, 倉田康孝. 講座:非線形力学系における分岐理論の解析・応用IV; 生体システムにみられる非線形現象:心臓不整脈の発症に関わる心筋細胞応答. システム/制御/情報. 2020. 64. 8. 322-327
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Yasutaka Kurata, Kunichika Tsumoto, Kenshi Hayashi, Ichiro Hisatome, Yuhichi Kuda, Mamoru Tanida. Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of Spontaneous SR Ca2+Release. Frontiers in Physiology. 2020. 10. 1545
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MISC (9):
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An integration of multi-level electrical activities in the heart: physiome/system biological approach towards in silico cardiology. 2011. 238. 3. 237-243
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村上 慎吾, 鈴木 慎悟, 倉智 嘉久, 津元 国親, 上島 豊, 野村 泰伸. 薬物誘発不整脈発生危険度の予測システム Arrhythmo predictor. 心電図. 2009. 29. Suppl.3. S-394
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Yoshinaga Tetsuya, Tsumoto Kunichika, Kawakami Hiroshi. Bifurcation and Global Behavior in Dynamically Coupled Neurons. Proceedings of the IEICE General Conference. 2002. 442-443
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Tsumoto K., Yoshinaga T., Kawakami H. Bifurcations in the Hodgkin-Huxley Equation with a Periodic α-function. Proceedings of the IEICE General Conference. 2001. 2001. 67-67
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SUGITA T., TSUMOTO K., KAWAKAMI H. Higher-harmonic Oscillations in a Tri-phase Duffing circuit. IEICE technical report. Nonlinear problems. 2000. 100. 469. 23-28
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Books (5):
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Phase response curves in neuroscience : theory, experiment, and analysis
Springer 2011 ISBN:9781493901548
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理論生物学 : 生命科学の新しい潮流
共立出版 2011 ISBN:9784320057135
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Computational electrophysiology : dynamical systems and bifurcations
Springer 2010 ISBN:9784431538615
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臨床医工学スキルアップ講座
大阪大学出版会 2010 ISBN:9784872593631
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Chaos in circuits and systems
World Scientific 2002 ISBN:9810249330
Lectures and oral presentations (155):
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第III群抗不整脈薬の催不整脈作用による致死性不整脈の起点としてのEAD誘発撃発活動形成の指向性
(第96回日本薬理学会年会 2023)
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心室不整脈の起点としてのEAD誘発撃発活動形成の指向性
(2023年度 生理学研究所心血管研究会 2023)
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運動ホルモンによる自律神経調節と高脂肪食性肥満への作用
(第32回日本病態生理学会大会 2023)
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心室性不整脈発症に関与する撃発活動形成の理論的機序: in silico研究
(第32回日本病態生理学会大会 2023)
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ヒト洞結節自動能の非線形力学的発生機序:数理モデル細胞の分岐解析による理論的検証
(第32回日本病態生理学会大会 2023)
more...
Education (4):
- 1999 - 2002 The University of Tokushima Graduate School of Engineering
- 1997 - 1999 The University of Tokushima Graduate School of Engineering
- 1995 - 1997 The University of Tokushima Faculty of Engineering Department of Electrical and Electronic Engineering
- 1990 - 1995 Miyagi National College of Technology Electric Engineering
Professional career (1):
Work history (5):
- 2018/08 - 現在 Kanazawa Medical University Faculty of Medicine Associate Professor
- 2010/10 - 2018/07 Osaka University Graduate School of Medicine Research Associate
- 2008/06 - 2010/09 Osaka University The Center for Advanced Medical Engineering and Informatics Specially Appointed Research Associate
- 2004/02 - 2008/05 Japan Science and Technology Agency Aihara Complexity Modelling Project, ERATO Postdoctoral research fellow
- 2002/04 - 2004/01 Takuma National College of Technology Department of Telecommunication Research assistant
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