TOHRU HOSOYAMA

ホソヤマトオル | TOHRU HOSOYAMA

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Cell biology

Research keywords (5)： Aging , Sarcopenia , Regenerative Medicine , Skeletal Muscle , Stem Cell

Research theme for competitive and other funds (14)：

2024 - 2029 デジタルバイオマーカーによるフレイル評価のための学術的基盤構築と包括的妥当性検証
2022 - 2026 高齢者における内在能力の簡易評価票の開発のためのコホート研究
2022 - 2025 運動による老化細胞除去機構の解明ー慢性呼吸器疾患治療モデルへの展開
2022 - 2025 認知機能の側面を含めたフレイルの血液バイオマーカーの探索および予防介入への展開 (AMED-Frailty Biomarker Study: AMED-FBI Study)
2021 - 2024 ビタミンDシグナルによる骨格筋の維持制御機構とサルコペニア病態生理の解明

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Papers (59)：

Kotaro Umamoto, Ryotaro Bouchi, Kotaro Soeda, Shosuke Satake, Tohru Hosoyama, Mitsuru Ohsugi, Kohjiro Ueki, Hiroshi Kajio. Association of biomarkers and Barthel Index with occurrence of age-related adverse health outcomes in individuals with diabetes. Journal of Diabetes Investigation. 2024. 15. 11. 1675-1683
Hiromichi Tsushima, Hirobumi Tada, Azusa Asai, Mikako Hirose, Tohru Hosoyama, Atsushi Watanabe, Taro Murakami, Masataka Sugimoto. Roles of pigment epithelium-derived factor in exercise-induced suppression of senescence and its impact on lung pathology in mice. Aging. 2024. 16. 13. 10670-10693
Tohru Hosoyama, Minako Kawai-Takaishi, Hiroki Iida, Yoko Yamamoto, Yuko Nakamichi, Tsuyoshi Watanabe, Marie Takemura, Shigeaki Kato, Akiyoshi Uezumi, Yasumoto Matsui. Lack of vitamin D signalling in mesenchymal progenitors causes fatty infiltration in muscle. Journal of cachexia, sarcopenia and muscle. 2024. 15. 3. 907-918
Mutsumi Suganuma, Motoki Furutani, Tohru Hosoyama, Risa Mitsumori, Rei Otsuka, Marie Takemura, Yasumoto Matsui, Yukiko Nakano, Shumpei Niida, Kouichi Ozaki, et al. Identification of potential blood-based biomarkers for frailty by using an integrative approach. Gerontology. 2024. 70. 6. 630-638
Minako Kawai-Takaishi, Yoshihiro Miyagawa, Takeshi Honda, Makoto Inui, Tohru Hosoyama. Postnatal Pdzrn3 deficiency causes acute muscle atrophy without alterations in endplate morphology. Biochemical and Biophysical Research Communications. 2024. 149542-149542

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Professional career (1)：

Ph.D (Chiba University)

Work history (7)：

2021/04 - 現在 National Center for Geriatrics and Gerontrogy Department of Musculoskeletal Disease Associate Professor
2017/06 - 2021/03 National Center for Geriatrics and Gerontology Dept. of Regenerative Medicine Section Chief
2012/05 - 2017/05 Yamaguchi University Graduate School of Medicine Dept. of Surgery and Clinical Science Assistant Professor
2010/07 - 2012/04 Univ. of Wisconsin-Madison Dept. of Comparative Biosciences Research Associate
2008/04 - 2010/06 Univ. of Texas Health Science Center at San Antonio Greehey Children's Cancer Research Institute Postdoctoral Fellow

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Committee career (5)：

2024/11 - 現在日本サルコペニア・フレイル学会評議員
2022/11 - 現在 The Japanese Society for Regenerative Medicine Representative
2020/09 - 2023/12 Frontiers in Aging Review Editor
2019/12 - 2021/06 第44回日本基礎老化学会大会プログラム委員
2017/07 - 2021/03 国立長寿医療研究センター実験動物管理委員

Awards (6)：

2024/11 - 第11回日本サルコペニア・フレイル学会大会優秀演題賞
2023/11 - 第10回日本サルコペニア・フレイル学会大会優秀演題賞
2023/06 - IAGG-AOR2023 Outstanding Poster Presentation Award
2019/10 - The 5th Asian Conference for Frailty and Sarcopenia Best Poster Award
2018/11 - 第5回日本サルコペニア・フレイル学会大会最優秀演題賞

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Association Membership(s) (6)：

Japan Association for Cachexia and Sarcopenia , 日本筋学会 , THE JAPANESE SOCIETY FOR REGENERTIVE MEDICINE(JSRM) , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , JAPAN SOCIETY FOR BIOMEDICAL GERONTOLOGY , 日本サルコペニア・フレイル学会

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