2018 - 2021 Elucidation of Muscle Aging using Random Mutagenesis
2015 - 2018 Development of transplantation therapy using hypoxically preconditioned cell sheets for lower limb ischemic ulcers
2015 - 2018 Activated cardiosphere-derived cell sheet therapy improves left ventricular function of old infarcted heart
2015 - 2018 Novel cell-based therapeutic strategies focusing on vessel maturation for severe peripheral vascular diseases
2015 - 2017 Challenges to rejuvenate aged-cardiac stem cells by genome editing to develop next generation therapeutic strategies for heart failure.
2014 - 2017 Clinical study on the protective effect of ischemic preconditioning against spinal cord injury
2014 - 2017 Synergistic effects of hypoxic preconditioning with apelin administration on cell-based therapy.
2013 - 2016 Therapeutic angiogenesis with preconditioned stem cells for clinical settings
2013 - 2015 Challenges for derivation of cardiac progenitors with microRNA regulation
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Papers (59)：
Kotaro Umamoto, Ryotaro Bouchi, Kotaro Soeda, Shosuke Satake, Tohru Hosoyama, Mitsuru Ohsugi, Kohjiro Ueki, Hiroshi Kajio. Association of biomarkers and Barthel Index with occurrence of age-related adverse health outcomes in individuals with diabetes. Journal of Diabetes Investigation. 2024
Hiromichi Tsushima, Hirobumi Tada, Azusa Asai, Mikako Hirose, Tohru Hosoyama, Atsushi Watanabe, Taro Murakami, Masataka Sugimoto. Roles of pigment epithelium-derived factor in exercise-induced suppression of senescence and its impact on lung pathology in mice. Aging. 2024
Tohru Hosoyama, Minako Kawai-Takaishi, Hiroki Iida, Yoko Yamamoto, Yuko Nakamichi, Tsuyoshi Watanabe, Marie Takemura, Shigeaki Kato, Akiyoshi Uezumi, Yasumoto Matsui. Lack of vitamin D signalling in mesenchymal progenitors causes fatty infiltration in muscle. Journal of cachexia, sarcopenia and muscle. 2024
Mutsumi Suganuma, Motoki Furutani, Tohru Hosoyama, Risa Mitsumori, Rei Otsuka, Marie Takemura, Yasumoto Matsui, Yukiko Nakano, Shumpei Niida, Kouichi Ozaki, et al. Identification of potential blood-based biomarkers for frailty by using an integrative approach. Gerontology. 2024
Minako Kawai-Takaishi, Yoshihiro Miyagawa, Takeshi Honda, Makoto Inui, Tohru Hosoyama. Postnatal Pdzrn3 deficiency causes acute muscle atrophy without alterations in endplate morphology. Biochemical and Biophysical Research Communications. 2024. 149542-149542
2021/04 - 現在 National Center for Geriatrics and Gerontrogy Department of Musculoskeletal Disease Associate Professor
2017/06 - 2021/03 National Center for Geriatrics and Gerontology Dept. of Regenerative Medicine Section Chief
2012/05 - 2017/05 Yamaguchi University Graduate School of Medicine Dept. of Surgery and Clinical Science Assistant Professor
2010/07 - 2012/04 Univ. of Wisconsin-Madison Dept. of Comparative Biosciences Research Associate
2008/04 - 2010/06 Univ. of Texas Health Science Center at San Antonio Greehey Children's Cancer Research Institute Postdoctoral Fellow
2005/07 - 2008/03 Univ. of Tokyo Dept. of Vet Phys Postdoctoral Fellow
2005/01 - 2005/06 Univ. of Tokyo Lab. of Cellular Biochemistry Postdoctoral Fellow
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Committee career (4)：
2022/11 - 現在 The Japanese Society for Regenerative Medicine Representative
2020/09 - 2023/12 Frontiers in Aging Review Editor
2019/12 - 2021/06 第44回日本基礎老化学会大会 プログラム委員
2017/07 - 2021/03 国立長寿医療研究センター 実験動物管理委員
Awards (5)：
2023/11 - 第10回日本サルコペニア・フレイル学会大会 優秀演題賞
2023/06 - IAGG-AOR2023 Outstanding Poster Presentation Award
2019/10 - The 5th Asian Conference for Frailty and Sarcopenia Best Poster Award
2018/11 - 第5回日本サルコペニア・フレイル学会大会 最優秀演題賞
2009/11 - Greehey Children's Cancer Research Institute GCCRI Director's Travel Grant Award
Association Membership(s) (6)：
Japan Association for Cachexia and Sarcopenia
, 日本筋学会
, THE JAPANESE SOCIETY FOR REGENERTIVE MEDICINE(JSRM)
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, JAPAN SOCIETY FOR BIOMEDICAL GERONTOLOGY
, 日本サルコペニア・フレイル学会
