Daisuke Yoshioka

ヨシオカダイスケ | Daisuke Yoshioka

Affiliation and department：

Research field (3)： Physiology , Neuroscience - general , Biophysics

Research keywords (4)： Axon initial segment , イオンチャネル , イノシトールリン脂質 , 1分子イメージング

Research theme for competitive and other funds (10)：

2022 - 2025 イノシトールリン脂質認識機構に立脚したイオンチャネルー脂質連関の理解
2022 - 2025 創薬基盤となる脂質によるイオンチャネル活性・動態調節機構の統括的理解
2023 - 2024 光操作を駆使したイオンチャネルの1分子動態解析
2021 - 2024 Visualization of turnover history of membrane proteins in CNS neuron
2023 - 2023 Single-Molecule Imaging to Reveal a Role of PI(4,5)P2-Channel Interactions in M-channel Trafficking Regulation in Neurons

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Papers (3)：

Daisuke Yoshioka, Yasushi Okamura. Coupling Between Functionality and Trafficking to the Axon Initial Segment in KCNQ2/3 K+Channels. 2024
Yasushi Okamura, Daisuke Yoshioka. What voltage-sensing phosphatases can reveal about the mechanisms of ion channel regulation by phosphoinositides. Biochemical Society Transactions. 2023. 51. 2. 827-839
Daisuke Yoshioka, Seiya Fukushima, Hiroyasu Koteishi, Daichi Okuno, Toru Ide, Satomi Matsuoka, Masahiro Ueda. Single-molecule imaging of PI(4,5)P2 and PTEN in vitro reveals a positive feedback mechanism for PTEN membrane binding. Communications Biology. 2020. 3. 1

MISC (5)：

好岡大輔, 岡村康司. 1分子イメージングによるPIP2を介したイオンチャネル動態制御の解析. 日本生理学雑誌(Web). 2022. 84. 1
YOSHIOKA Daisuke, YOSHIOKA Daisuke, KOTEISHI Hiroyasu, OKUNO Daichi, MATSUOKA Satomi, IDE Toru, UEDA Masahiro, UEDA Masahiro. PTEN-PI (4, 5)P₂ positive feedback mechanism for stabilizing asymmetric PI (3, 4, 5)P₃ localization in migrating cell. 生物物理(Web). 2018. 58. Supplement 1-2
好岡大輔, 福島誠也, 福島誠也, 奥野大地, 松岡里実, 井出徹, 上田昌宏, 上田昌宏. In vitro1分子イメージングによるPTEN-PI(4,5)P₂相互作用の解析. 日本細胞生物学会大会(Web). 2017. 69th
YOSHIOKA Daisuke, FUKUSHIMA Seiya, FUKUSHIMA Seiya, KOTEISHI Hiroyasu, OKUNO Daichi, MATSUOKA Satomi, IDE Toru, UEDA Masahiro, UEDA Masahiro. A mechanism of asymmetric PTEN distribution revealed by in vitro single-molecule imaging analysis. 日本細胞生物学会大会(Web). 2016. 68th
YOSHIOKA Daisuke, FUKUSHIMA Seiya, FUKUSHIMA Seiya, KOTEISHI Hiroyasu, OKUNO Daichi, MATSUOKA Satomi, IDE Toru, UEDA Masahiro, UEDA Masahiro. Phosphatidylinositol lipid PI(4,5)P2 enhances membrane binding of PTEN revealed by single-molecule imaging on artificial lipid bilayers. 日本蛋白質科学会年会プログラム・要旨集. 2016. 16th

Lectures and oral presentations (15)：

Single-Molecule Imaging Reveals Activity-Dependent Regulation Mechanism of M-channel Trafficking in Neurons
(NEURO2024 2024)
Correlation of M-channel activity and trafficking dynamics in neurons
(The 101st Annual Meeting of The Physiological Society of Japan 2024)
Single-Molecule Imaging to Reveal a Role of PI(4,5)P2-Channel Interactions in M-channel Trafficking Regulation in Neurons
(10th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS 2023))
神経における電位依存性カリウムチャネルの時空間動態解析
(2023年生理学研究所研究会 2023)
Imaging analysis of Nav and Kv channels trafficking mechanism in neurons
(The 46th Annual Meeting of the Japan Neuroscience Society 2023)

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Education (2)：

Professional career (1)：

Work history (4)：

Awards (6)：

2024/10 - Basic Biology Forum of Young Scientists, Osaka Univ. Best Presentation Award Single-molecule imaging reveals a correlation mechanism between M-channel functionality and trafficking dynamics in neurons
2023/11 - 10th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS 2023) k-MEDI hub Young Investigator Award Single-Molecule Imaging to Reveal a Role of PI(4,5)P2-Channel Interactions in M-channel Trafficking Regulation in Neurons
2021/11 - 第113回近畿生理学談話会若手優秀発表賞 1分子イメージングによるPIP2を介したイオンチャネル動態制御の解析
2021/06 - 一般財団法人蛋白質研究奨励会令和3年度金子・成田研究奨励金イノシトールリン脂質PIP2によるイオンチャネルの活性化と動態変化の相関
2020/02 - 国立研究開発法人理化学研究所理化学研究所理事長感謝状

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Association Membership(s) (4)：

日本神経科学学会 , PHYSIOLOGICAL SOCIETY OF JAPAN , Biophysical Society , 日本生物物理学会

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