Kiyoshi Teshigawara

テシガワラキヨシ | Kiyoshi Teshigawara

Homepage URL (1)： http://kaken.nii.ac.jp/d/r/40403737.ja.html

Research field (4)： Pharmacology , Metabolism and endocrinology , Pathobiochemistry , Medical biochemistry

Research keywords (23)：糖尿病 , 脊髄損傷 , 突起伸展 , フィラミン , 糖脂質代謝 , アストロサイト , 軸索 , 骨格筋 , 神経 , 樹状突起 , デノソミン , グリア瘢痕 , シグナル伝達 , GLUT4トランスロケーション , インスリン受容体 , 可溶性インスリンレセプター , 血糖指標 , 転写因子 , Gq共役受容体 , 血中可溶性インスリン受容体 , インスリン , AS160 , 生理活性

Research theme for competitive and other funds (14)：

2020 - 2023 敗血症関連DAMPs拮抗因子HRGの血管保護作用機序の解明
2019 - 2022 Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.
2019 - 2022 Analysis dynamics of HMGB1 as a biosensor molecule and its multiple functions
2017 - 2020 敗血症治療のためのHRG血液製剤の創出
2016 - 2019 Functional characterization of histidine-rich glycoprotein (HRG) under the inflammatory conditions.

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Papers (80)：

Handong Qiao, Yuta Morioka, Dengli Wang, Keyue Liu, Shangze Gao, Hidenori Wake, Daiki Ousaka, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori. Protective effects of an anti-4-HNE monoclonal antibody against liver injury and lethality of endotoxemia in mice. European Journal of Pharmacology. 2023. 950. 175702-175702
Shangze Gao, Keyue Liu, Wenhan Ku, Dengli Wang, Hidenori Wake, Handong Qiao, Kiyoshi Teshigawara, Masahiro Nishibori. Histamine induced high mobility group box-1 release from vascular endothelial cells through H-1 receptor. FRONTIERS IN IMMUNOLOGY. 2022. 13
Dengli Wang, Daiki Ousaka, Handong Qiao, Ziyi Wang, Kun Zhao, Shangze Gao, Keyue Liu, Kiyoshi Teshigawara, Kenzo Takada, Masahiro Nishibori. Treatment of Marmoset Intracerebral Hemorrhage with Humanized Anti-HMGB1 mAb. CELLS. 2022. 11. 19
Wang Dengli, Ousaka Daiki, Qiao Handong, Wang Ziyi, Zhao Kun, Teshigawara Kiyoshi, Nishibori Masahiro. Treatment of intracerebral hemorrhage with humanized a-HMGB1 mAb in non-human primate brain. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 95. 2-YIA-43
Kazuki Hatayama, Ray H. Chen, Jordan Hanson, Kiyoshi Teshigawara, Joseph Qiu, Andre Santoso, Clémence Disdier, Sakura Nakada, Xiaodi Chen, Masahiro Nishibori, et al. High-mobility group box-1 and inter-alpha inhibitor proteins: In vitro binding and co-localization in cerebral cortex after hypoxic-ischemic injury. FASEB Journal. 2021. 35. 3

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MISC (42)：

Ayaka Tomohiro, Shinya Ukeshima, Shiho Kitaoka, Xiang Nie, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Masahiro Nishibori, Tomoyuki Furuyashiki. Roles and Mechanisms of Neuroinflammation in Stress and Depression. NEUROPSYCHOPHARMACOLOGY. 2019. 44. SUPPL 1. 120-121
Dengli Wang, Katsuyaku Ryu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori. Anti-HMGB1 therapy for intracerebral hemorrhage. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S98-S98
Hidenori Wake, Shuji Mori, Hideo Takahashi, Keyue Liu, Kiyoshi Teshigawara, Masahiro Nishibori. The role of histidine-rich glycoprotein on NETosis and immunothrombosis in septic condition. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S251-S251
Dengli Wang, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori. Anti-HMGB1 therapy for intracerebral hemorrhage. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2016. 130. 3. S88-S88
Hidenori Wake, Shuji Mori, Hideo Takahashi, Keyue Liu, Kiyoshi Teshigawara, Masahiro Nishibori. Imaging of neutrophil circulation in septic microvascular environment. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2016. 130. 3. S217-S217

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Patents (7)：

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Professional career (1)：

博士(医学) (神戸大学)

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