Rchr
J-GLOBAL ID:201301036827144393   Update date: May. 13, 2024

Mitsuru Morimoto

モリモト ミツル | Mitsuru Morimoto
Affiliation and department:
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/70544344.ja.html
Research field  (1): Respiratory medicine
Research keywords  (5): 発現制御 ,  発生・分化 ,  呼吸器 ,  シグナル伝達 ,  細胞・組織
Research theme for competitive and other funds  (10):
  • 2023 - 2026 Establishment of an in vitro human pulmonary fibrosis model using a novel culture system of alveolar organoids
  • 2021 - 2023 Development of human alveolar organoid culture method using complete medium
  • 2020 - 2023 Establishment of human airway organoid by understanding airway development in single-cell resolution
  • 2019 - 2021 Developing alveolar organoid recapitulating injury-regeneration-imflammation-fibrosis
  • 2017 - 2020 Reconstructive analysis of molecular regulation in epithelial stem cell and its niche in the lung
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Papers (32):
  • Yasunori Enomoto, Hiroaki Katsura, Takashi Fujimura, Akira Ogata, Saori Baba, Akira Yamaoka, Miho Kihara, Takaya Abe, Osamu Nishimura, Mitsutaka Kadota, et al. Autocrine TGF-β-positive feedback in profibrotic AT2-lineage cells plays a crucial role in non-inflammatory lung fibrogenesis. Nature communications. 2023. 14. 1. 4956-4956
  • Takashi Fujimura, Yasunori Enomoto, Hiroaki Katsura, Taisaku Ogawa, Saori Baba, Akira Ogata, Akira Yamaoka, Katsuyuki Shiroguchi, Mitsuru Morimoto. Identifying a Lung Stem Cell Subpopulation by Combining Single-Cell Morphometrics, Organoid Culture, and Transcriptomics. Stem cells (Dayton, Ohio). 2023
  • Keishi Kishimoto, Kentaro Iwasawa, Alice Sorel, Carlos Ferran-Heredia, Lu Han, Mitsuru Morimoto, James M Wells, Takanori Takebe, Aaron M Zorn. Directed differentiation of human pluripotent stem cells into diverse organ-specific mesenchyme of the digestive and respiratory systems. Nature protocols. 2022. 17. 11. 2699-2719
  • Satomi Yogosawa, Makiko Ohkido, Takuro Horii, Yasumasa Okazaki, Jun Nakayama, Saishu Yoshida, Shinya Toyokuni, Izuho Hatada, Mitsuru Morimoto, Kiyotsugu Yoshida. Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. Communications Biology. 2021. 4. 1
  • Hirofumi Kiyokawa, Mitsuru Morimoto. Molecular crosstalk in tracheal development and its recurrence in adult tissue regeneration. Developmental dynamics : an official publication of the American Association of Anatomists. 2021. 250. 11. 1552-1567
more...
MISC (12):
  • 森本充. 呼吸器の複雑性の理解と再構成 -器官形成とオルガノイドー. 生体の科学;形態形成の統合的理解. 2022. 73. 4
  • 清川寛文, 森本充. 発生と再生に共通する組織幹細胞の増殖制御メカニズムTgfβ-Id軸の発見. 実験医学;カレントトピックス. 2022. 40. 3
  • 中山彰吾, 森本充. 呼吸器発生の解明が導く気管・肺胞オルガノイド培養技術の開発. 実験医学;人発生に挑むオルガノイド. 2021
  • 榎本泰典, 森本充. 肺胞オルガノイド. 臨床免疫・アレルギー学. 2021. 76. 4
  • 岸本圭史, 森本充. 呼吸器オルガノイド. 実験医学増刊号;オルガノイド実験スタンダード,第3章 組織幹細胞オルガノイド. 2019. 37. 5
more...
Professional career (1):
  • 博士(生命科学)
Work history (5):
  • 2012/10 - 現在 RIKEN
  • 2010/04 - 2012/09 国立遺伝学研究所 発生工学研究室
  • 2006/04 - 2010/03 Washington University in St.Louis
  • 2003/04 - 2006/03 国立遺伝学研究所 発生工学研究室
  • 2000/04 - 2003/03 東京薬科大学大学院 生命科学研究科
Awards (5):
  • 2019/06 - 花王芸術科学財団 花王科学賞
  • 2015/04 - 日本呼吸器学会学術講演会 International Session Award 英語口頭発表優秀者
  • 2014/04 - 文部科学省 文部科学大臣表彰 若手科学者賞
  • 2013/04 - International Session Award
  • 2012/07 - FASEB Science Research Conferences Jo Rae Wright Award
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