Rchr
J-GLOBAL ID:201301038388809980   Update date: Sep. 23, 2024

Takamatsu Hiroyuki

タカマツ ヒロユキ | Takamatsu Hiroyuki
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/70401932.ja.html
Research field  (1): Hematology and oncology
Research keywords  (26): 抗HLAモノクローナル抗体 ,  二重特異性抗体 ,  CAR-T ,  マルチカラーフローサイトメトリー ,  次世代シークエンサー ,  質量分析 ,  微小残存病変 ,  多発性骨髄腫 ,  モエシン ,  自己抗体 ,  骨髄不全 ,  ハイブリドーマ ,  ノックアウトマウス ,  抗モエシン抗体 ,  再生不良性貧血 ,  TNF-α ,  ERK1 ,  2 ,  抗DRS-1抗体 ,  慢性関節リウマチ ,  FcRγ ,  hnRNPK ,  シグナル伝達 ,  免疫抑制療法 ,  PNH型血球 ,  P同型血球
Research theme for competitive and other funds  (9):
  • 2021 - 2025 Development of novel anti-HLA monoclonal antibodies and CAR-T therapy using B cells derived from donors
  • 2018 - 2021 Production of monoclonal antibodies using B cells derived from patients and their clinical application
  • 2015 - 2018 Development of novel treatments of myeloma based on MRD using next-generation sequencing and protein-array assay
  • 2012 - 2015 Identification of myelosuppressive cytokines taking advantage of genomic abnormalities of leukocytes in patients with aplastic anemia
  • 2009 - 2011 Generation of bone marrow failure model mice by autoantibodies inducing cytokine production
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Papers (91):
  • Laurent Garderet, Luuk Gras, Linda Koster, Laurien Baaij, Nada Hamad, Anita Dsouza, Noel Estrada-Merly, Parameswaran Hari, Wael Saber, Andrew J Cowan, et al. Global characteristics and outcomes of autologous hematopoietic stem cell transplantation for newly diagnosed multiple myeloma: A study of the worldwide network for blood and marrow transplantation (WBMT). American journal of hematology. 2024
  • Kento Morita, Shigehiro Karashima, Toshiki Terao, Kotaro Yoshida, Takeshi Yamashita, Takeshi Yoroidaka, Mikoto Tanabe, Tatsuya Imi, Yoshitaka Zaimoku, Akiyo Yoshida, et al. 3D CNN-based Deep Learning Model-based Explanatory Prognostication in Patients with Multiple Myeloma using Whole-body MRI. Journal of Medical Systems. 2024. 48. 1
  • Yasunori Kogure, Hiroshi Handa, Yuta Ito, Masaki Ri, Yuichi Horigome, Masaki Iino, Yoriko Harazaki, Takahiro Kobayashi, Masahiro Abe, Tadao Ishida, et al. ctDNA improves prognostic prediction in relapsed/refractory MM receiving ixazomib, lenalidomide, and dexamethasone. Blood. 2024
  • Yoshitaka Zaimoku, Takamasa Katagiri, Noriharu Nakagawa, Tatsuya Imi, Hiroyuki Maruyama, Hiroyuki Takamatsu, Ken Ishiyama, Hirohito Yamazaki, Toshihiro Miyamoto, Shinji Nakao. HLA Class I Allele Loss and Bone Marrow Transplantation Outcomes in Immune Aplastic Anemia. Transplantation and cellular therapy. 2023
  • Hiroki Mizumaki, Dung Cao Tran, Kohei Hosokawa, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Hiroyuki Takamatsu, Hirohito Yamazaki, Ken Ishiyama, Rena Yamazaki, Hiroshi Fujiwara, et al. Minor GPI(-) granulocyte populations in aplastic anemia and healthy individuals derived from a few PIGA-mutated hematopoietic stem progenitor cells. Blood cancer journal. 2023. 13. 1. 165-165
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MISC (113):
  • Laurent Garderet, Luuk Gras, Linda Koster, Anita D'Souza, Noel Estrada-Merly, Parameswaran Hari, Wael Saber, Andrew J. Cowan, Minako Iida, Shinichiro Okamoto, et al. Worldwide Network for Blood and Marrow Transplantation (WBMT) Global Study on Baseline Characteristics and Clinical Outcomes in NEWLY Diagnosed Multiple Myeloma Patients Undergoing Upfront Autologous STEM Cell Transplantation, a Study Off 61,725 Patients from 629 Centers. BLOOD. 2022. 140. 4839-4842
  • Laurent Garderet, Luuk Gras, Linda Koster, Anita D'Souza, Noel Estrada-Merly, Parameswaran Hari, Wael Saber, Andrew J. Cowan, Minako Iida, Shinichiro Okamoto, et al. International Differences in Baseline Characteristics and Practice Patterns in Patients with NEWLY Diagnosed Multiple Myeloma Undergoing Upfront Autologous STEM Cell Transplantation. BLOOD. 2022. 140. 5225-5227
  • Yoshitaka Zaimoku, Hiroki Mizumaki, Takeshi Yoroidaka, Noriharu Nakagawa, Tatsuya Imi, Hiroyuki Maruyama, Mikoto Tanabe, Noriaki Tsuji, Ryota Urushihara, Kohei Hosokawa, et al. HLA Class I Allele-Specific Pathology Defines Clinical Manifestations of Immune Aplastic Anemia. BLOOD. 2022. 140
  • 川島隼人, 丸山裕之, 萩原剛志, 吉野裕貴, 村宏樹, 井美達也, 吉田晶代, 材木義隆, 細川晃平, 高松博幸, et al. A case of late graft failure with PNH type positive blood cells post transplantation. 日本造血・免疫細胞療法学会総会プログラム・抄録集. 2022. 45th
  • 吉野裕貴, 井美達也, 川島隼人, 萩原剛志, 村宏樹, 松浦絵里香, 材木義隆, 細川晃平, 丸山裕之, 吉田晶代, et al. Acute ATLL in which PTCy haplotransplantation was performed with HHV-6 encephalitis treatment. 日本造血・免疫細胞療法学会総会プログラム・抄録集. 2022. 45th
more...
Patents (3):
  • ヒト抗HLAモノクローナル抗体の作製方法
  • 再生不良性貧血患者血清に存在する自己抗体の検出方法
  • 細胞の懸濁培養法
Professional career (2):
  • PhD (Kanazawa University)
  • MSc (Kyoto University)
Work history (6):
  • 2022/04 - 現在 Kanazawa University Faculty of Transdisciplinary Sciences for Innovation, Institute of Transdisciplinary Sciences for Innovation Professor
  • 2023/04 - 2024/03 カリフォルニア大学サンフランシスコ校臨床検査医学部門 客員教授
  • 2021/04 - 2022/03 Faculty of Transdisciplinary Sciences for Innovation, Institute of Transdisciplinary Sciences for Innovation, Kanazawa University Associate Professor
  • 2017/07 - 2021/03 Hematology and Respiratory Medicine, Kanazawa University Associate Professor
  • 2011/04 - 2017/06 Hematology and Respiratory Medicine, Kanazawa University Assistant Professor
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Committee career (13):
  • 2024 - 現在 日本骨髄腫学会 理事
  • 2023 - 現在 日本臨床検査医学会 臨床検査ガイドライン「多発性骨髄腫とM蛋白血症」担当
  • 2021 - 現在 日本血液学会 日本血液学会総会プログラム編集委員(多発性骨髄腫領域)
  • 2019/04 - 現在 日本血液学会 造血器腫瘍診療ガイドライン委員会-小委員会委員・疾患責任者(再発難治性骨髄腫
  • 2018/04 - 現在 日本血液学会 多発性骨髄腫研究実行委員
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Awards (9):
  • 2022/05 - 公益財団法人三谷研究開発支援財団 研究助成
  • 2017/07 - 金沢大学 新型コロナウイルス感染症対策支援ファンド
  • 2017/06 - 北陸地区国立大学 平成29年度北陸地区国立大学学術研究連携支援入選
  • 2014/12 - 先進医薬研究振興財団 2015年度血液医学分野 一般研究助成入選
  • 2014/09 - 北國新聞社 第28回北國がん基金研究助成入選
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Association Membership(s) (11):
Asian Myeloma Network (AMN) 会員 ,  日本癌学会 ,  日本生物工学会 ,  日本骨髄腫学会 ,  米国血液学会(International member) ,  日本臨床検査医学会 ,  日本老年医学会 ,  日本輸血・細胞治療学会 ,  日本造血細胞学会 ,  日本血液学会 ,  日本内科学会
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