Research theme for competitive and other funds (7):
2023 - iPS細胞由来CAR-T細胞
2023 - ワクチンを含む抗ウイルス薬 in vivo評価系に資する新規HTLV-1感染小動物モデルの作製
2020 - 2022 ハブ咬傷時に投与する安全な抗毒素抗体の開発
2018 - 2021 Expression and immunogenicity of recombinant vaccinia virus containing the HTLV-1 env gene
2021 - 抗CADM1-CAR-T細胞
2017 - 2020 抗ハブ毒モノクローナル抗体
2019 - 2023 抗CADM1抗体
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Papers (23):
Yuetsu Tanaka, Reiko Tanaka, Naoki Imaizumi, Mariko Mizuguchi, Yoshiaki Takahashi, Masaki Hayashi, Takashi Miyagi, Junnosuke Uchihara, Kazuiku Ohshiro, Hiroaki Masuzaki, et al. A protective role of HTLV-1 gp46-specific neutralizing and antibody-dependent cellular cytotoxicity-inducing antibodies in progression to adult T-cell leukemia (ATL). Frontiers in immunology. 2022. 13. 921606-921606
Mariko Mizuguchi, Mitsuyoshi Takatori, Shugo Sakihama, Manami Yoshita-Takahashi, Naoki Imaizumi, Yoshiaki Takahashi, Hiroo Hasegawa, Kennosuke Karube, Takuya Fukushima, Masataka Nakamura, et al. Acute type adult T-cell leukemia cells proliferate in the lymph nodes rather than in peripheral blood. Cancer gene therapy. 2022
Mizuguchi M, Takahashi Y, Tanaka R, Fukushima T, Tanaka Y. Conservation of a Neutralization Epitope of Human T-cell Leukemia Virus Type 1 (HTLV-1) among Currently Endemic Clinical Isolates in Okinawa, Japan. Pathogens (Basel, Switzerland). 2020. 9. 2