Rchr
J-GLOBAL ID:201301043207447783   Update date: Sep. 02, 2024

Mitsuru Ishikawa

イシカワ ミツル | Mitsuru Ishikawa
Affiliation and department:
Job title: Senior Assistant Professor
Other affiliations (2):
Research keywords  (21): マルチスケール脳 ,  scRNA-Seq ,  Bipolar disorder ,  Schizophrenia ,  Genome Editing ,  Epilepsy ,  神経科学 ,  neuroscience ,  developmental disorder ,  transcription factor ,  synapse ,  stem cell ,  iPS Cells ,  lncRNA ,  包括脳ネットワーク ,  神経分化 ,  発達障害 ,  自閉症スペクトラム ,  神経幹細胞 ,  iPS細胞 ,  転写因子
Research theme for competitive and other funds  (18):
  • 2024 - 2027 発達性てんかん性脳症の個別化医療を促進させる細胞種特異的iPS神経系培養基盤の導出
  • 2023 - 2027 発達性てんかん性脳症の個別化医療を促進させる細胞種特異的iPS神経系培養基盤の導出
  • 2023 - 2026 Molecular pathology investigation for targeted therapy of intractable pediatric epilepsy via mTOR pathway hyperactivation
  • 2022 - 2025 Custom generation of human brain cells: establishment of in vitro differentiation system for whole cell types
  • 2018 - 2023 Constructive understanding of bipolar disorder and schizophrenia by transomics and modeling
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Papers (53):
  • Yusuke Masano, Chika Saegusa, Mitsuru Ishikawa, Tatsuo Matsunaga, Hideyuki Okano, Masato Fujioka. Generation of an induced pluripotent stem cell line (KEIUi008-A) from a hearing loss patient with an A1555G mutation in mitochondrial DNA. Stem cell research. 2024. 78. 103452-103452
  • Nicolas Leventoux, Satoru Morimoto, Mitsuru Ishikawa, Shiho Nakamura, Fumiko Ozawa, Reona Kobayashi, Hirotaka Watanabe, Sopak Supakul, Satoshi Okamoto, Zhi Zhou, et al. Aberrant CHCHD2-associated mitochondriopathy in Kii ALS/PDC astrocytes. Acta neuropathologica. 2024. 147. 1. 84-84
  • Ryohei Takada, Michihiro Toritsuka, Takahira Yamauchi, Rio Ishida, Yoshinori Kayashima, Yuki Nishi, Mitsuru Ishikawa, Kazuhiko Yamamuro, Minobu Ikehara, Takashi Komori, et al. Granulocyte macrophage colony-stimulating factor-induced macrophages of individuals with autism spectrum disorder adversely affect neuronal dendrites through the secretion of pro-inflammatory cytokines. Molecular autism. 2024. 15. 1. 10-10
  • Hiroya Kobayashi, Koji Ueda, Satoru Morimoto, Mitsuru Ishikawa, Nicolas Leventoux, Ryogen Sasaki, Yoshifumi Hirokawa, Yasumasa Kokubo, Hideyuki Okano. Protein profiling of extracellular vesicles from iPSC-derived astrocytes of patients with ALS/PDC in Kii peninsula. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023. 44. 12. 4511-4516
  • 喜山 公輔, 渡部 博貴, 石川 充, 小林 菜々子, 篠崎 宗久, 嶋田 弘子, 岡野 栄之. APOE4-脳オルガノイドのマウスへの移植によるアルツハイマー病の病態解明への試み. Dementia Japan. 2023. 37. 4. 678-678
more...
MISC (27):
  • OTOMO Asako, OTOMO Asako, NISHIJIMA Keiko, MURAKAMI Yuta, ISHIKAWA Mitsuru, KIMURA Hiroshi, KIMURA Hiroshi, HADANO Shinji, HADANO Shinji. Evaluation of an FUS-linked ALS cellular model using the microfluidic cell culture system. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • YUDAHIRA Haruka, SATO Kai, SHIMAKURA Kento, ISHIKAWA Mitsuru, OTOMO Asako, HADANO Shinji. Functional association between two ALS-linked genes NEK1 and ALS2 affects neuronal phenotypes. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
  • OTOMO Asako, OTOMO Asako, NISHIJIMA Keiko, MURAKAMI Yuta, ISHIKAWA Mitsuru, KIMURA Hiroshi, KIMURA Hiroshi, HADANO Shinji, HADANO Shinji. Development of a microdevice suitable for the analysis of axonal morphology of motor neurons differentiated from human iPSCs. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
  • QIAN Emi, 吉松祥, 石川充, 岡野栄之. Visualization of subtype-specific GABAergic interneurons derived from human pluripotent stem cells. 日本神経化学会大会抄録集(Web). 2021. 64th
  • 銭映美, 石川充, 吉松祥, 岡野栄之. ヒトiPS細胞からのサブサイプ特異的な抑制性神経細胞の分化誘導と可視化. 日本再生医療学会総会(Web). 2021. 20th
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Lectures and oral presentations  (14):
  • bHLH型転写因子発現による神経分化プラットホームを用いた神経疾患解析へのアプローチ
    (【シンポジウム】BPCNPNPPP4 2022)
  • Diverse approaches to neuronal cell culture from iPS cells: toward a modeling for neurodevelopmental disorders
    (【シンポジウム】第95回日本薬理学会年会 2022)
  • 神経疾患の病態・創薬スクリーニングのためのロバストな神経分化誘導
    (【特別講演】リプロセル 第20回ウェビナー 2021)
  • 【Symposium】A Platform for Pathological Analysis Based on Robust and Subtype-specific Neuronal Differentiation from Human iPS Cells
    (5th Stanford-Keio Joint Seminar, SLDDDRS Webinar Series 2021)
  • ヒトiPS細胞を利用した神経変性疾患・精神疾患の病態・創薬スクリーニングの実例
    (【特別講演】第16回薬学部研究発表会, 高崎健康福祉大学 2021)
more...
Professional career (1):
  • 薬学 (富山大学)
Association Membership(s) (11):
日本再生医療学会 ,  日本薬学会 ,  日本生化学会 ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPAN NEUROSCIENCE SOCIETY ,  International Society for Stem Cell Research ,  Society for Neuroscience ,  日本薬理学会 ,  日本生物学的精神医学会 ,  日本ゲノム編集学会
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