Tadahiro Numakawa

ヌマカワタダヒロ | Tadahiro Numakawa

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/40425690.ja.html

Research field (2)： Psychiatry , Neuroscience - general

Research keywords (8)： neural stem cells , cortex , Brain-derived neurotrophic factor , Brain disease , Neuroscience , Pharmacology , Neurotrophic factor , central nervous system

Research theme for competitive and other funds (17)：

2023 - 2026 iPS細胞を用いたメラノーマに対する新規がん免疫療法の開発
2020 - 2023 Development of novel pathological analysis and medicine in neuropathic Gaucher disease.
2020 - 2023 Role of the interaction between microglia and neuron in the defected neuronal function in the lysosomal storage disease
2017 - 2020 ゴーシェー病II型患者由来iPS細胞を用いた新規治療薬の開発
2016 - 2019 ヒト大脳皮質様オルガノイドを用いた脳疾患の病態解明

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Papers (112)：

Tadahiro Numakawa, Ryutaro Kajihara. An Interaction among Neurotrophic Factor BDNF and Stress-Related Glucocorticoids in the Pathophysiology of Alzheimer’s Disease. 2023
Tadahiro Numakawa, Ryutaro Kajihara. Involvement of brain-derived neurotrophic factor signaling in the pathogenesis of stress-related brain diseases. Frontiers in Molecular Neuroscience. 2023. 16
Tadahiro Numakawa, Ryutaro Kajihara. Neurotrophins and Other Growth Factors in the Pathogenesis of Alzheimer’s Disease. Life. 2023. 13. 3
Shuichi CHIBA, Tadahiro NUMAKAWA, Takuya MURATA, Mitsumori KAWAMINAMI, Toshiyuki HIMI. Enhanced social reward response and anxiety-like behavior with downregulation of nucleus accumbens glucocorticoid receptor in BALB/c mice. Journal of Veterinary Medical Science. 2023. 85. 1. 30-39
Tadahiro Numakawa, Haruki Odaka. The Role of Neurotrophin Signaling in Age-Related Cognitive Decline and Cognitive Diseases. International Journal of Molecular Sciences. 2022. 23. 14. 7726-7726

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MISC (38)：

山田弘, 五十嵐芳暢, 中津則之, 山縣友紀, 秋丸裕司, 秋丸恵理佳, 堀本勝久, 福井一彦, 江良択実, 沼川忠広, et al. 肝毒性インフォマティクスシステムの構築(AMEDプロジェクト). The Journal of Toxicological Sciences. 2019. 44. Suppl. S326-S326
T. Numakawa, N. Adachi, S. Chiba, E. Kumamaru, Y. Ooshima, K. Hashido, H. Kunugi. Possible mechanism underlying negative influence of glucocorticoids on BDNF-mediated neuronal function. JOURNAL OF NEUROCHEMISTRY. 2012. 123. 122-122
C. Wakabayashi, T. Numakawa, Y. Kiyama, T. Manabe, H. Kunugi, Y. Iwakura. Behavioral phenotype observed in IL-1Ra KO after chronic mild immobilization stress. JOURNAL OF NEUROCHEMISTRY. 2012. 123. 124-124
S. Kishi, T. Numakawa, H. Mizuno, N. Adachi, H. Kunugi, K. Hashido. Targeted molecule of brain-specific microRNA-132. JOURNAL OF NEUROCHEMISTRY. 2012. 123. 118-118
鈴木辰吾, 清末和之, 邱紅麗, 沼川忠広, 伊丹千晶, 笠間健嗣, 小島正己, 田中光一, 三木崇範, 竹内義喜. BDNFによるニューロンのコレステロール合成誘導とプレシナプス成熟のメカニズム. 解剖学雑誌. 2012. 87. 2. 43-43

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Education (2)：

1997 - 2000 Osaka University
1995 - 1997 大阪大学大学院理学研究科生物化学専攻修士課程

Professional career (1)：

理学博士 (大阪大学)

Work history (10)：

2023/10 - 現在 Kumamoto University Institute of Molecular Embryology and Genetics Assistant Professor
2014/11 - 2023/09 Kumamoto University
2004/05 - 2016/04 Tokyo Medical University
2010/04 - 2014/10 (独)国立精神・神経医療研究センター疾病研究第三部室長
2007/04 - 2011/03 Tokyo Medical and Dental University

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Committee career (2)：

2011 - 現在日本神経化学会評議員
2011 - 2012 日本神経化学会将来計画委員

Awards (4)：

2010/03 - 国立精神・神経センター神経研究所平成21年度優秀論文賞受賞
2009/06 - 日本神経化学会第10回日本神経化学会奨励賞受賞
2005/12 - 長寿科学振興財団長寿科学振興財団理事長賞受賞
2005/03 - 国立精神・神経センター神経研究所平成絵16年度優秀論文賞受賞

Association Membership(s) (5)：

THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE JAPAN NEUROSCIENCE SOCIETY , JAPANESE SOCIETY OF BIOLOGICAL PSYCHIATRY , Society for Neuroscience , American Society for Biochemistry and MolecularBiology

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