YAMAMOTO Kiyofumi

ヤマモトキヨフミ | YAMAMOTO Kiyofumi

Affiliation and department：

Research field (2)： Clinical pharmacy , Physiology

Research theme for competitive and other funds (10)：

2023 - 2026 ATP受容体による島皮質グリア細胞-抑制性シナプス増強で生じる抗疼痛-不安作用の解明
2022 - 2025 The study using chemical genetics to reveal regulation mechanisms of insulocortical hyperactivities in the neuropathic pain model
2020 - 2023 味覚の臨界期を探るためのGRINレンズによる覚醒マウスの脳内イメージング法の確立
2019 - 2022 Mechanisms of insulocortical inhibitory synaptic transmission plasticity that regulates neuropathic pain
2016 - 2019 Trigeminal nerve transection-induced neuroplastic changes in the somatosensory and insular cortices in a rat ectopic pain model

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Papers (26)：

Kiyofumi Yamamoto, Qi-Yu Chen, Zhaoxiang Zhou, Masayuki Kobayashi, Min Zhuo. Cortical nitric oxide required for presynaptic long-term potentiation in the insular cortex. Philosophical Transactions of the Royal Society B: Biological Sciences. 2024. 379. 1906
Kiyofumi Yamamoto, Satoshi Kosukegawa, Masayuki Kobayashi. P2X receptor- and postsynaptic NMDA receptor-mediated long-lasting facilitation of inhibitory synapses in the rat insular cortex. Neuropharmacology. 2024. 245. 109817-109817
Yuka Nakaya, Kiyofumi Yamamoto, Masayuki Kobayashi. Descending projections from the insular cortex to the trigeminal spinal subnucleus caudalis facilitate excitatory outputs to the parabrachial nucleus in rats. Pain. 2023. 164. 3. e157-e173
Hirose K, Nakaya Y, Kitano K, Saito Y, Kaneko R, Yanagawa Y, Yamamoto K, Shirakawa T, Kobayashi M. Differential regulation of medium spiny and cholinergic neurons in the nucleus accumbens core by the insular and medial prefrontal cortices in the rat. Pflügers Archiv. 2021. 473. 12. 1911-1924
Synchronous inhibitory synaptic inputs to layer II/III pyramidal neurons in the murine barrel cortex2021. Brain Research. 2021. 1773. 14. 147686

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MISC (7)：

篠田雅路, 小林真之, 藤田智史, 山本清文, 久保亜抄子, 坐間学, 臼井緑, 岩田幸一. 上顎神経障害性疼痛抑制効果に対するミノサイクリン投与法の検討. PAIN RESEARCH. 2018. 33. 2. 149-149
Yamamoto K and Kobayashi M. Opposite roles in short-term plasticity for N-type and P/Q-type voltage-dependent calcium channels in GABAergic neuronal connections in the rat cerebral cortex. J Neurosci. 2018. 38. 9814-9828
Kiyofumi Yamamoto, Noriaki Koshikawa, Masayuki Kobayashi. Target-cell dependent synaptic modulation of inhibitory synapses by nitric oxide in rat insular cortex. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 180P-180P
Yuko Koyanagi, Kiyofumi Yamamoto, Yoshiyuki Oi, Noriaki Koshikawa, Masayuki Kobayashi. Presynaptic interneuron subtype-dependent modulation of synaptic transmission by beta-adrenoceptors in rat cerebral cortex. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 112. 186P-186P
Masayuki Kobayashi, Yuko Koyanagi, Kiyofumi Yamamoto, Noriaki Koshikawa. beta-Adrenoceptors differentially modulate inhibitory synaptic transmission depending on presynaptic interneuron subtype. NEUROSCIENCE RESEARCH. 2010. 68. E229-E229

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Lectures and oral presentations (12)：

P/Q- and N-type voltage-dependent calcium channels determine short-term plasticity of GABAergic synapses in the rat insular cortex.
(第62回歯科基礎医学会学術大会 2020)
カイニン酸受容体ー一酸化窒素」経路で誘発する島皮質シナプス長期可塑性
(142回薬理学会関東部会 2020)
Novel synaptic pathway originated from the olfactory bulb suppresses the excitation of pyramidal neurons in the insular cortex
(2nd Pain and Emotions Summer Meeting. 2018)
interneurons receive excitatory inputs from the piriform cortex.The agranular insular cortical fast-spiking
(第59回歯科基礎医学学会学術大会 2017)
N- and P/Q- type calcium channels differentially regulate short-term plasticity in rat cortical inhibitory synapses.
(第40回日本神経科学学会 2017)

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Professional career (1)：

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