Rchr
J-GLOBAL ID：201301058024931977   Update date: May. 06, 2024

TAKAESU Giichi

タカエス ギイチ | TAKAESU Giichi
Affiliation and department：
University of the Ryukyus Tropical Biosphere Research Center

About University of the Ryukyus Tropical Biosphere Research Center


Job title： Associate Professor
Homepage URL  (2)： https://hostdefense.skr.u-ryukyu.ac.jp ,  http://www.tbc.u-ryukyu.ac.jp
Research field  (4)： Bacteriology ,  Immunology ,  Cell biology ,  Molecular biology
Research keywords  (8)： マクロファージ ,  炎症 ,  プログラム細胞死 ,  細胞内シグナル伝達 ,  Macrophages ,  Inflammation ,  Programmed cell death ,  Signal transduction
Research theme for competitive and other funds  (10)：
  • 2021 - 2024 Analysis of type 3 immune responses against M. tuberculosis infection and application to boost vaccine
  • 2020 - 2023 Analysis of molecular mechanism of mitochondrial damage and immune suppression induced by Mycobacterium tuberculosis
  • 2018 - 2021 Analysis of multiple defense mechanisms of "type 3 immune response" in mycobacteria infected lungs
  • 2018 - 2021 A role of TAB3 in host defense against mycobacterial infection
  • 2015 - 2018 Molecular mechanisms of cell death in macrophages and foam cells
Show all
Papers (50)：
  • Tanveer Ali, Huong Minh Nguyen, Naeem Abbas, Osamu Takeuchi, Shizuo Akira, Toshihiko Suzuki, Goro Matsuzaki, Giichi Takaesu. TAK1-binding protein 2 (TAB2) and TAB3 are redundantly required for TLR-induced cytokine production in macrophages. International Immunology. 2024
  • Tomomi Kurane, Tetsuro Matsunaga, Tomoaki Ida, Kazuko Sawada, Akira Nishimura, Masayuki Fukui, Masayuki Umemura, Masaaki Nakayama, Naoya Ohara, Sohkichi Matsumoto, et al. GRIM-19 is a target of mycobacterial Zn2+ metalloprotease 1 and indispensable for NLRP3 inflammasome activation. The FASEB Journal. 2022. 36. 1. e22096
  • 中田 光紀, 高江洲 義一, 梅村 正幸, 松崎 吾朗. 結核菌の病原因子Zmp1を標的とするVHH抗体の開発2. 琉球医学会誌. 2021. 40. 1-4. 68-68
  • NOBUYUKI MARUYAMA, MASATO UMIKAWA, HIROFUMI MATSUMOTO, TESSHO MARUYAMA, KAZUHIDE NISHIHARA, TOSHIYUKI NAKASONE, AKIRA MATAYOSHI, TAKAHIRO GOTO, FUSAHIRO HIRANO, AKIRA ARASAKI, et al. miR-935 Inhibits Oral Squamous Cell Carcinoma and Targets Inositol Polyphosphate-4-phosphatase Type IA (INPP4A). Anticancer Research. 2020. 40. 11. 6101-6113
  • Nakasone N, Ogura Y, Higa N, Toma C, Koizumi Y, Takaesu G, Suzuki T, Yamashiro T. Effects of Psidium guajava leaf extract on secretion systems of Gram-negative enteropathogenic bacteria. Microbiology and immunology. 2018. 62. 7. 444-453
ｍore...
MISC (19)：
  • 藏根友美, 高江洲義一, 高江洲義一, 松永哲郎, 井田智章, 澤田和子, 梅村正幸, 梅村正幸, 赤池孝章, 松崎吾朗, et al. A molecular mechanism of IL-β inhibition by mycobacterial effector protein. 日本生体防御学会学術総会講演抄録集. 2021. 32nd
  • 高江洲義一, 高江洲義一, 藏根友美, 澤田和子, 西村明, 松永哲郎, 井田智章, 梅村正幸, 梅村正幸, 赤池孝章, et al. A molecular mechanism of IL-1β inhibition by mycobacterial effector protein. 日本生体防御学会学術総会講演抄録集. 2020. 31st
  • 梅村正幸, 梅村正幸, 梅村正幸, 藏根友美, 中山真彰, 大原直也, 高江洲義一, 高江洲義一, 高江洲義一, 松崎吾朗, et al. 病原因子Zmp1欠損マイコバクテリアによるT細胞免疫応答への影響. 日本インターフェロン・サイトカイン学会学術集会抄録集. 2019. 84th
  • 梅村正幸, 梅村正幸, 木村倫和, 岩橋晃平, 藏根友美, 照屋尚子, 中山真彰, 大原直也, 高江洲義一, 高江洲義一, et al. マイコバクテリア病原因子Zmp1の自然免疫およびT細胞免疫応答への影響. 日本熱帯医学会大会プログラム抄録集. 2019. 60th
  • 梅村正幸, 儀間香南子, 高江洲義一, 中江進, 岩倉洋一郎, 松崎吾朗. マイコバクテリア感染肺に誘導されるIL-17A産生細胞の多様性. 日本インターフェロン・サイトカイン学会学術集会抄録集. 2018. 83. 96
ｍore...
Lectures and oral presentations  (14)：
  • A molecular mechanism of IL-1β inhibition by mycobacterial effector protein
    (The 93rd Annual Meeting of Japanese Society for Bacteriology 2020)
  • Identification and functional analysis of a host protein targeted by mycobacterial effector Zmp1
    (The 93rd Annual Meeting of Japanese Society for Bacteriology 2020)
  • Mechanism of mycobacteria specific IL-17A production of BCG infected lung-derived TCRgammadelta T cells
    (The 48th Annual Meeting of the Japanese Society for Immunology 2019)
  • Molecular basis of a mycobacterial effector protein for the development of host-directed therapy of tuberculosis
    (The 42nd Annual Meeting of the Molecular Biology Society of Japan 2019)
  • Effects of mycobacteria-derived Zmp1 on innate and T-cell immune responses
    (The 60th Annual Meeting for the Japanese Society of Tropical Medicine 2019)
ｍore...
Education (3)：
  • 1998 - 2001 Nagoya University Graduate School of Science Division of Biological Science
  • 1996 - 1998 Nagoya University Graduate School of Science Division of Biological Science
  • 1992 - 1996 Nagoya University School of Science
Professional career (2)：
  • Ph. D. in Molecular Biology (Nagoya University)
  • M.S. (Nagoya University)
Work history (7)：
  • 2016/05 - University of the Ryukyus Tropical Biosphere Research Center Associate Professor
  • 2012/10 - 2016/04 University of the Ryukyus Assistant Professor
  • 2009/01 - 2012/09 Keio University School of Medicine, Center for Integrated Medical Research
  • 2005/06 - 2008/12 Kyushu University Medical Institute of Bioregulation
  • 2003/06 - 2005/05 Mount Sinai School of Medicine Postdoc
Show all
Association Membership(s) (10)：
日本生体防御学会 ,  日本免疫学会 ,  日本細菌学会 ,  日本細胞生物学会 ,  日本分子生物学会 ,  Japanese Society for Host Defense Research ,  Japanese Society for Immunology ,  Japan Society for Bacteriology ,  Japan Society for Cell Biology ,  The Molecular Biology Society of Japan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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