Rchr
J-GLOBAL ID：201301063989868015   Update date: Apr. 29, 2024

Saigusa Daisuke

サイグサ ダイスケ | Saigusa Daisuke
Affiliation and department：
Teikyo University Faculty of Pharma-Science

About Teikyo University Faculty of Pharma-Science


Job title： Associate Professor
Other affiliations (1)：
  • Tohoku University  Tohoku Medical Megabank Organization   Visiting Associate Professor
Research field  (1)： Pharmaceuticals - analytical and physicochemistry
Research keywords  (7)： Biomarker ,  Chromatography ,  Mass Spectrometry Imaging ,  Lipidomics ,  Analytical Chemistry ,  Mass Spectrometry ,  Metabolomics
Research theme for competitive and other funds  (20)：
  • 2023 - 2027 尿毒素による細胞内代謝失調を標的とした高齢者の慢性腎臓病合併症の治療開発
  • 2023 - 2026 Elucidation of spatio-temporal regulation mechanisms of brain pharmacokinetics by blood-brain, arachnoid and cerebrospinal fluid barriers
  • 2023 - 2026 投影型MSイメージング法による脂質ラフト含有スフィンゴ脂質の可視化技術開発
  • 2021 - 2024 前眼部組織間のトランスオミクス解析による包括的な眼圧上昇機序の解明
  • 2020 - 2023 高空間分解能MSイメージング法によるS1P組織分布の高感度可視化
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Papers (137)：
  • Mitsuharu Sato, Eiji Hishinuma, Naomi Matsukawa, Yoshiko Shima, Daisuke Saigusa, Ikuko N Motoike, Mana Kogure, Naoki Nakaya, Atsushi Hozawa, Shinichi Kuriyama, et al. Dietary habits and plasma lipid concentrations in a general Japanese population. Metabolomics : Official journal of the Metabolomic Society. 2024. 20. 2. 34-34
  • Sherif Rashad, Shadi Al-Mesitef, Abdulrahman Mousa, Yuan Zhou, Daisuke Ando, Guangxin Sun, Tomoko Fukuuchi, Yuko Iwasaki, Jingdong Xiang, Shane R Byrne, et al. Translational response to mitochondrial stresses is orchestrated by tRNA modifications. bioRxiv : the preprint server for biology. 2024
  • Masaru Doshi, Yujin Natori, Akira Ishii, Daisuke Saigusa, Shiro Watanabe, Makoto Hosoyamada, Yutaka Hirashima-Akae. Hypothermia increases adenosine monophosphate and xanthosine monophosphate levels in the mouse hippocampus, preventing their reduction by global cerebral ischemia. Scientific Reports. 2024. 14. 1
  • Tomoyuki Akiyama, Daisuke Saigusa, Takushi Inoue, Chiho Tokorodani, Mari Akiyama, Rie Michiue, Atsushi Mori, Eiji Hishinuma, Naomi Matsukawa, Takashi Shibata, et al. Exploration of urine metabolic biomarkers for new-onset, untreated pediatric epilepsy: A gas and liquid chromatography mass spectrometry-based metabolomics study. Brain & development. 2024
  • Kota Sato, Daisuke Saigusa, Taiki Kokubun, Amane Fujioka, Qiwei Feng, Ritsumi Saito, Akira Uruno, Naomi Matsukawa, Michiko Ohno-Oishi, Hiroshi Kunikata, et al. Reduced glutathione level in the aqueous humor of patients with primary open-angle glaucoma and normal-tension glaucoma. npj aging. 2023. 9. 1. 28-28
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MISC (156)：
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Books (5)：
  • メタボロミクス実践ガイド : サンプル調製からデータ解析まで、あなたに合った実験デザインと達人テクニック
    羊土社 2021 ISBN:9784758122511
  • Uremic toxins and guanidino compounds
    2017
  • Kidney Science
    2016
  • Bioactive Lipid Mediators
    Springer Nature 2015
  • Bioactive Lipid Mediators
    2013
Lectures and oral presentations  (27)：
  • 生体内メタボローム解析技術開発と疾患バイオマーカー探索研究への応用
    (第47回日本医用マススペクトル学会年会 2022)
  • Lipidomic Profiling in the Large-Scale Cohort for Biomarker Discovery and the Importance of Separation Science
    (Lipidomics, Gordon Research Conference 2022)
  • Evaluation for quantified values of lipidomic profiling in a large-scale cohort
    (iSLS10 2022)
  • Addressing accuracy of reference values in a large-scale cohort by MS-based metabolomics
    (Virtual Podium Asia Pacific (VPAP) 2021)
  • 疾患関連リゾリン脂質の高精密定量を目的とした分離分析系の開発について
    (第32回クロマトグラフィー科学会議 2021)
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Education (2)：
  • 2006 - 2009 Tohoku University Graduate School of Pharmaceutical Sciences
  • 2002 - 2006 Hoshi University
Professional career (1)：
  • Ph.D. (Tohoku University)
Work history (8)：
  • 2021/10 - 現在 Tohoku University Tohoku Medical Megabank Organization Associate Professor
  • 2021/10 - 現在 Faculty of Pharma-Scienses Laboratory of Biomedical and Analytical Sciences Associate Professor
  • 2022/09 - 2023/10 Turin University Visiting Professor
  • 2020/10 - 2021/09 University of Turin Visiting Professor
  • 2015/08 - 2021/09 Tohoku University Tohoku Medical Megabank Organization / Graduate School of Medicine Senior Assistant Professor
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Committee career (2)：
  • 2021/06 - 現在 The Mass Spectrometry Society of Japan Director
  • 2017/09 - 現在 Japanese Society for Biomedical Mass Spectrometry Councilor
Awards (4)：
  • 2022/09 - Japanese Society for Biomedical Mass Spectrometry Encouragement Award
  • 2014/05 - The Mass Spectrometry Society of Japan Best Presentation Award
  • 2011/10 - Research Group of Ganidino Compounds Young Encouragement Award
  • 2011/09 - Japanese Society for Biomedical Mass Spectrometry Poster Award
Association Membership(s) (11)：
Lipidomics-Standards-Initiative ,  Japan Society of Clinical Chemistry ,  Japan Human Proteome Organization ,  Metabolomics Society ,  The Mass Spectrometry Society of Japan ,  Japanese Society for Biomedical Mass Spectrometry ,  日本薬学会 ,  Japanese Society for Pharmaceutical Palliative Care and Sciences ,  The Japanese Biochemical Society ,  American Society of Mass Spectrometry ,  Mass Spectrometry Imaging Society
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