Iwasaki Tetsushi

イワサキテツシ | Iwasaki Tetsushi

Affiliation and department：
Job title： Assistant Professor

Research field (2)： Functional biochemistry , Cell biology

Research theme for competitive and other funds (10)：

2021 - 2024 Establishment of a basis for the development of anti-aging medicine using spontaneous senescent cells
2022 - 2023 がん細胞から生じる老化細胞の形成機構とその除去方法の確立
2020 - 2023 Basic research for the development of novel anticancer drugs targeting senescent cells induced by cancer treatment
2020 - 2022 ミネラルナノ粒子による高度細胞増殖技術の開発とそのメカニズム解析
2015 - 2018 多次元フローサイトメトリー法によるシグナル分子修飾の解析

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Papers (44)：

Ryoko Katasho, Taiki Nagano, Tetsushi Iwasaki, Shinji Kamada. Nectin-4 regulates cellular senescence-associated enlargement of cell size. Scientific Reports. 2023. 13. 1
Keitaro Nakagawa, Taiki Nagano, Ryoko Katasho, Tetsushi Iwasaki, Shinji Kamada. Integrin β1 transduces the signal forLY6D-induced macropinocytosis and mediates senescence-inducing stress-evoked vacuole formation viaFAK. FEBS Letters. 2022. 596. 21. 2768-2780
Yuki Yoshikawa, Keisuke Yuzu, Naoki Yamamoto, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Tetsushi Iwasaki, Masatomo So, Yuji Goto, Atsuo Tamura, et al. Pathway Dependence of the Formation and Development of Prefibrillar Aggregates in Insulin B Chain. Molecules. 2022. 27. 13. 3964-3964
Watson P Folk, Alpana Kumari, Tetsushi Iwasaki, Erica K Cassimere, Slovénie Pyndiah, Elizabeth Martin, Kelly Homlar, Daitoku Sakamuro. New Synthetic Lethality Re-Sensitizing Platinum-Refractory Cancer Cells to Cisplatin In Vitro: The Rationale to Co-Use PARP and ATM Inhibitors. International journal of molecular sciences. 2021. 22. 24
Taiki Nagano, Yuto Awai, Shione Kuwaba, Taiichi Osumi, Kentaro Mio, Tetsushi Iwasaki, Shinji Kamada. Riboflavin transporter SLC52A1, a target of p53, suppresses cellular senescence by activating mitochondrial complex II. Molecular Biology of the Cell. 2021. 32. 21. mbc.E21-05

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MISC (28)：

Alpana Kumari, Tetsushi Iwasaki, Walson P. Folk, Amy L. Abdulovic-Cui, Slovenie Pyndiah, George C. Prendergast, John M. Sedivy, Daitoku Sakamuro. c-MYC preserves genomic integrity during DNA replication: a paradigm shift of c-MYC. MOLECULAR CANCER RESEARCH. 2016. 14
T. Fukumoto, T. Iwasaki, T. Okada, T. Hashimoto, Y. Moon, M. Sakaguchi, Y. Fukami, C. Nishigori, M. Oka. High expression of Mcl-1 mediated by MEK-ERK1/2-STAT3 signaling pathway protects melanocytes and melanoma cells against ultraviolet B-induced apoptosis. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015. 135. S107-S107
Alexander A Tokmakov, Vasily E Stefanov, Tetsushi Iwasaki, Ken-Ichi Sato, Yasuo Fukami. Calcium signaling and meiotic exit at fertilization in Xenopus egg. International journal of molecular sciences. 2014. 15. 10. 18659-76
M. Oka, M. Sakaguchi, T. Iwasaki, Y. Fukami, C. Nishigori. Ser727 phosphorylation in STAT3 plays a crucial role in cell survival and nuclear translocation of STAT3 in human melanocytes and melanoma cells. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2012. 132. S24-S24
M. Sakaguchi, M. Oka, T. Iwasaki, Y. Fukami, C. Nishigori. Ser727 phosphorylation in STAT3 plays a crucial role in nuclear translocation of STAT3 and growth in human melanoma cells and melanocytes. PIGMENT CELL & MELANOMA RESEARCH. 2011. 24. 4. 791-792

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Lectures and oral presentations (83)：

FAD依存性酵素LSD2によるSASP因子の発現制御
(若手フロンティア研究会 2023 2023)
STEAP3は細胞内Fe2+とFADに依存して老化細胞にアポトーシスを誘導する
(第46回日本分子生物学会年会 2023 2023)
FAD依存性リシン特異的脱メチル化酵素2によるSASP因子の発現制御
(第46回日本分子生物学会年会 2023 2023)
老化細胞特異的な空胞形成を制御するLY6Dのタンパク質構造に基づく機能解析
(第46回日本分子生物学会年会 2023 2023)
LY6Dに依存した老化細胞特異的空胞形成におけるATP1A1の機能解析
(第46回日本分子生物学会年会 2023 2023)

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Professional career (2)：

Awards (1)：

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