Toyoshima Manabu

トヨシママナブ | Toyoshima Manabu

Homepage URL (1)： http://kaken.nii.ac.jp/d/r/90582750.ja.html

Research field (1)： Psychiatry

Research keywords (13)：包括脳ネットワーク , 統合失調症 , NG2細胞 , NG2(+)細胞 , FABP7 , シグナルパスウェイ , iPS細胞 , 遺伝子改変マウス , 神経分化 , GABAA受容体 , 22q11.2欠失症候群 , カナビノイド受容体 , DNAChip

Research theme for competitive and other funds (5)：

2018 - 2021 カルボニルストレスにおけるCRMP2のAGE修飾の解析
2015 - 2018 統合失調症の神経発達障害に関わるmiRNAの分子基盤の解明
2013 - 2014 Effect of carbonyl stress on neural differentiation and development
2011 - 2012 Etiology elucidation of schizophrenia that focus on oligodendrocyte progenitor cells
2010 - 2010 The production of NG2 (+) cell conditional dysfunction mice for purposes of elucidation of schizophrenia.

Papers (23)：

Tetsuo Ohnishi, Shabeesh Balan, Manabu Toyoshima, Motoko Maekawa, Hisako Ohba, Akiko Watanabe, Yoshimi Iwayama, Yuko Fujita, Yunfei Tan, Yasuko Hisano, et al. Investigation of betaine as a novel psychotherapeutic for schizophrenia. EBioMedicine. 2019. 45. 432-446
Min Ma, Qian Ren, Jun Yang, Kai Zhang, Zhongwei Xiong, Tamaki Ishima, Yaoyu Pu, Sung Hee Hwang, Manabu Toyoshima, Yoshimi Iwayama, et al. Key role of soluble epoxide hydrolase in the neurodevelopmental disorders of offspring after maternal immune activation. Proceedings of the National Academy of Sciences of the United States of America. 2019. 116. 14. 7083-7088
Maekawa M, Ohnishi T, Balan S, Hisano Y, Nozaki Y, Ohba H, Toyoshima M, Shimamoto C, Tabata C, Wada Y, et al. Thiosulfate promotes hair growth in mouse model. Bioscience, biotechnology, and biochemistry. 2019. 83. 1. 114-122
Akiko Matsuura, Tamaki Ishima, Yuko Fujita, Yoshimi Iwayama, Shunsuke Hasegawa, Ryouka Kawahara-Miki, Motoko Maekawa, Manabu Toyoshima, Yusuke Ushida, Hiroyuki Suganuma, et al. Dietary glucoraphanin prevents the onset of psychosis in the adult offspring after maternal immune activation. Scientific reports. 2018. 8. 1. 2158-2158
Shabeesh Balan, Manabu Toyoshima, Takeo Yoshikawa. Contribution of induced pluripotent stem cell technologies to the understanding of cellular phenotypes in schizophrenia. Neurobiology of Disease. 2018. 131. 104162

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MISC (2)：

前川素子, 豊島学, 吉川武男. 現代社会とうつ病(6)遺伝子発現からみたうつ病の神経科学. 最新医学. 2011. 66. 10. 2400-2405
Brain science (82) NG2[(+)] cells and psychiatric illnesses. Psychiatry. 2010. 17. 4. 401-406

Work history (1)：

2013 - RIKEN

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