Takashi Matsuhira

マツヒラタカシ | Takashi Matsuhira

Affiliation and department：
Job title： Lecturer
Homepage URL (1)： https://chem.naramed-u.ac.jp/profile_matsuhira.html

Research field (4)： Biochemistry , Polymer chemistry , Structural/physical organic chemistry , Bioorganic chemistry

Research theme for competitive and other funds (8)：

2024 - 2028 Supramolecular hemoglobin hydrogel as a pro-healing dressing material for ischemic wounds
2021 - 2023 Starburst hemoglobin polymer with controlled physical properties as a red blood cell substitute
2021 - 2023 人工赤血球の一酸化炭素/酸素運搬機能の最適化による出血性ショック蘇生効果の向上
2017 - 2020 Synthesis and in vivo characterization of polymer-multilinked hemoglobin assembly as artificial oxygen carrier
2017 - 2020 Artificial red cells with a defense function to oxidative stress

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Papers (16)：

Semhar Ghirmai, Haizhou Wu, Michael Axelsson, Takashi Matsuhira, Hiromi Sakai, Ingrid Undeland. Exploring how plasma- and muscle-related parameters affect trout hemolysis as a route to prevent hemoglobin-mediated lipid oxidation of fish muscle. Scientific Reports. 2022. 12. 1. 13446
T. Matsuhira, K. Yamamoto, H. Sakai. Construction of Hemoglobin-Based Oxygen Carriers Using Supramolecular Polymerization. Artificial Blood. 2021. 29. 1. 50-56
Takashi Matsuhira, Hiromi Sakai. Artificial oxygen carriers, from nanometer- to micrometer-sized particles, made of hemoglobin composites substituting for red blood cells. Particuology. 2021. 64. 43-55
Takashi Matsuhira, Hiromi Sakai. Entropy-Driven Supramolecular Ring-Opening Polymerization of a Cyclic Hemoglobin Monomer for Constructing a Hemoglobin-PEG Alternating Polymer with Structural Regularity. Biomacromolecules. 2021. 22. 5. 1944-1954
M. Yamada, T. Matsuhira, K. Yamamoto, H. Sakai. Antioxidative pseudo-enzymatic activity of NADH coexisting with hemoglobin and its application to artificial red cells. Artificial Blood. 2020. 28. 1. 49-56

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MISC (40)：

松平崇, 酒井宏水. ヘモグロビンを架橋点に持つ超分子ポリマーゲルの刺激応答性. 人工血液. 2023. 31. 1. 31
Takashi Matsuhira, Hiromi Sakai. Ring-opening Polymerization of Huge Cyclic Monomers of PEGylated Hemoglobin (Division Topics). Chemistry & Chemical Industry. 2023. 76. 4. 261
松平崇, 酒井宏水. 二個のヘモグロビンが四分岐PEGに結合した二環式モノマーの合成と超分子開環重合による可逆的な自己組織化. 人工血液. 2022. 30. 1. 41
松平崇, 酒井宏水. ヘモグロビンを四分岐PEGで分子間架橋した超分子ゲルの合成とレオロジー特性. 日本バイオレオロジー学会誌. 2022. 36. 2. 56
T. Matsuhira, H. Sakai. 四分岐PEGを用いたヘモグロビンハイドロゲルの構築. Artificial Blood. 2021. 29. 1. 35

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Books (3)：

基礎生命化学ー分子から見た私たちー
かきく書房 2022 ISBN:9784991205200
Nanobiotherapeutic Based Blood Substitutes (Regenerative Medicine, Artificial Cells and Nanomedicine)
World Scientific Publishing Co. Pte. Ltd., Singapore 2021 ISBN:9789811228681
Nanobiotherapeutic Based Blood Substitutes (Regenerative Medicine, Artificial Cells and Nanomedicine)
World Scientific Publishing Co. Pte. Ltd., Singapore 2021 ISBN:9789811228681

Lectures and oral presentations (84)：

A synthetic strategy for hemoglobin-PEG architectures using supramolecular polymerization
(The 19th International Symposium on Blood Substitutes 2024 (ISBS 2024) 2024)
複合抗酸化剤の抗酸化能と作用機序 -相乗効果とリポソーム化効果について-
(第74回日本薬学会関西支部総会・大会 2024)
Multi-stimuli responsive hydrogel using subunit interaction of hemoglobin
(2024)
Oxygen-responsive viscoelasticity of hemoglobin-PEG gel
(2024)
Viscoelastic Switching of Supramolecular Polymer Gels Cross-linked by Inter-subunit Interactions in Hemoglobin
(2024)

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Education (3)：

2005 - 2008 Osaka University Graduate School of Science Department of Macromolecular Science
2003 - 2005 Osaka University Graduate School of Science Department of Macromolecular Science
1999 - 2003 Osaka University School of Science Department of Chemistry

Professional career (1)：

Work history (3)：

2021 - 現在 Nara Medical University Department of Chemistry 講師
2009 - 2021 Nara Medical University Department of Chemistry 助教
2008 - 2009 Osaka University Department of the Administration for Safety and Hygiene, laboratory of chemistry for environment and safety Ph.D researcher

Awards (4)：

2021/03/02 - 令和2年度最優秀FD活動(教養教育)表彰
2019/11/23 - Young Excellent Abstract Award of the 17th International Symposium on Blood Substitutes & Oxygen Therapeutics (XVII-ISBS-2019)
2019/03/04 - 平成30年度最優秀FD活動(教養教育)表彰
2018/12/04 - Best Oral Presentation Award of the International Symposium for Materials Scientists “Inspiration for Innovation by Interaction” (ISMS III)

Association Membership(s) (3)：

日本化学会 , 高分子学会 , 日本血液代替物学会

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