Okada Nobuhiro

オカダノブヒロ | Okada Nobuhiro

Affiliation and department：

Research field (2)： Molecular biology , Tumor biology

Research keywords (2)：分子生物学 , 腫瘍生物学

Research theme for competitive and other funds (14)：

2022 - 2025 Development of a breast cancer preventive treatment targeting the nutritional environment of fetal stage
2019 - 2022 Elucidation of the NFYA function in the acquisition of resistance to therapeutic drugs in breast cancer
2021 - 2022 胎児期環境により決定される疾患発症リスク診断法の開発
2021 - 2022 Development of a breast cancer preventive treatment targeting the nutritional environment of fetal stage
2021 - 2022 がん特異的糖代謝バランスを標的とした新規がん治療法の開発

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Papers (19)：

Mirei Date, Ai Miyamoto, Tomoko Honjo, Tsugumi Shiokawa, Hiroko Tada, Nobuhiro Okada, Junichiro Futami. Hydrophobicity and molecular mass-based separation method for autoantibody discovery from mammalian total cellular proteins. Protein science : a publication of the Protein Society. 2023. 32. 10. e4771
Nobuhiro Okada, Chihiro Ueki, Masahiro Shimazaki, Goki Tsujimoto, Susumu Kohno, Hayato Muranaka, Kiyotsugu Yoshikawa, Chiaki Takahashi. NFYA promotes malignant behavior of triple-negative breast cancer in mice through the regulation of lipid metabolism. Communications biology. 2023. 6. 1. 596-596
Goki Tsujimoto, Rin Ito, Kei Yoshikawa, Chihiro Ueki, Nobuhiro Okada. NFYA promotes the anti-tumor effects of gluconeogenesis in hepatocellular carcinoma through the regulation of PCK1 expression. Frontiers in cell and developmental biology. 2022. 10. 983599-983599
Jindan Sheng, Susumu Kohno, Nobuhiro Okada, Nobuyuki Okahashi, Kana Teranishi, Fumio Matsuda, Hiroshi Shimizu, Paing Linn, Naoko Nagatani, Minako Yamamura, et al. Treatment of Retinoblastoma 1-Intact Hepatocellular Carcinoma With Cyclin-Dependent Kinase 4/6 Inhibitor Combination Therapy. Hepatology (Baltimore, Md.). 2021. 74. 4. 1971-1993
Juan Du, Yanning Xu, Saki Sasada, Aung Ko Ko Oo, Ghmkin Hassan, Hafizah Mahmud, Apriliana Cahya Khayrani, Md Jahangir Alam, Kazuki Kumon, Ryo Uesaki, et al. Signaling Inhibitors Accelerate the Conversion of mouse iPS Cells into Cancer Stem Cells in the Tumor Microenvironment. Scientific reports. 2020. 10. 1. 9955-9955

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MISC (25)：

岡田宣宏, 辻本剛己. 乳がん細胞系譜転換における脂質代謝制御機構の解明. 金沢大学がん進展制御研究所がんの転移・薬剤耐性に関わる先導的共同研究拠点. 2020. 2019
岡田宣宏. Elucidation of the mechanism of cancer heterogeneity for preemptive breast cancer therapy. Annual Report of the Okayama Foundation for Science and Technology. 2020. 29
岡田宣宏, 辻本剛己, 吉川清次, 高橋智聡. NFYA splicing variant regulates the malignant progression of breast cancer. 日本癌学会学術総会抄録集(Web). 2020. 79th
辻本剛己, 高橋智聡, 岡田宣宏. Antitumor effect of gluconeogenesis induced by NFYA. 日本癌学会学術総会抄録集(Web). 2020. 79th
植木ちひろ, 辻本剛己, 河野晋, 高橋智聡, 岡田宣宏. 脂肪酸合成制御を介したNFYAによる乳がん悪性化機構への影響. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd

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Education (2)：

2005 - 2010 大阪大学大学院生命機能研究科 5年一貫制博士課程
2001 - 2005 Meiji University School of Agriculture Department of Life Sciences

Professional career (1)：

博士(理学) (大阪大学)

Work history (5)：

2023 - 現在 Kyoto Prefectural University of Medicine Graduate School of Medical Science
2018 - 2023 Okayama University
2016 - 2018 Kanazawa University Cancer Research Institute
2014 - 2016 京都大学大学院医学研究科DSKプロジェクト特定助教
2010 - 2014 University of California, Berkeley

Awards (4)：

2021 - 岡山県産業振興財団令和3年度岡山県産業振興財団科学技術賞
2018/07 - 岡山工学振興会平成30年度岡山工学振興会科学技術賞
2015/09 - 文部科学省科学研究費新学術領域研究「がん研究分野等の特性を踏まえた支援活動」平成27年度がん若手研究者ワークショップベストトーク賞
2009/10 - 日本生化学会第82回日本生化学会大会優秀プレゼンテーション賞

Association Membership(s) (1)：

THE JAPANESE CANCER ASSOCIATION

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