Research field (1)：
Environmental and pharmaceutical development resources
Research keywords (1)：
Medicinal plants, Crude drug, Kampo medicine, Metabolomics, Mass spectrometry, Chemical ecology
Research theme for competitive and other funds (10)：
2022 - 2025 Research on functional enhancement of medicinal plants using allelochemicals derived from Asteraceae plants
2017 - 2022 Development and dissemination of theoretical mass-spectral libraries
2018 - 2021 Studies on the induction of secondary metabolites in medicinal plants of the Apiaceae family using insect-derived elicitors
2015 - 2018 Quality improvement of medicinal plants using insect-plant interaction
2009 - 2011 Analysis on genetic, chemical and pharmacological diversity of medicinal plants, towards sustainable uses of traditional medicines
2009 - 2010 Kampo-Kinome解析によるケミカルバイオロジーの展開
2008 - 2010 Studies on endogenous neuronal mediator with responsibility for anti-dementia effect of Kampo medicine
2007 - 2008 神経変性疾患に有効な伝統薬物分子の探索とその治療戦略
2005 - 2007 Investigation on Kampo Drug Resources in Asia and Analysis on Diversity ofMedicinal Plants
2005 - 2007 Identification of the intrinsic molecules which are involved in the generation of disease, and the analysis of the molecular mechanisms and functions, by using Wakan-yaku, Japanese traditional systematized medicine
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Papers (68)：
Yuto Nishidono, Hina Yahata, Kotaro Niwa, Aoi Kitajima, Yasuhiro Tezuka, Shiro Watanabe, Ken Tanaka. Fluctuations in the chemical constituents of <i>Panax ginseng</i> subterranean tissues with cultivation duration. Traditional & Kampo Medicine. 2022. 9. 1. 41-48
Nishidono Y, Niwa K, Kitajima A, Watanabe S, Tezuka Y, Arita M, Takabayashi J, Tanaka K. α-Linolenic acid in Papilio machaon larvae regurgitant induces a defensive response in Apiaceae. Phytochemistry. 2021. 188. 112796. 1-7
Sasaki K, Sasaki D, Sasaki K, Nishidono Y, Yamamori A, Tanaka K, Kondo A. Growth stimulation of Bifidobacterium from human colon by daikenchuto in an in vitro model of human intestinal microbiota. Scientific Reports. 2021. 11. 4580. 1-8
Zhuoer Chen, Shiro Watanabe, Yuto Nishidono, Ken Tanaka. Boiogito extract alters fecal bile acid profile in mice: Possible roles in changes in fecal and liver lipid levels. Traditional & Kampo Medicine. 2020. 7. 3. 138-145
Xoan Thi Le, Hang Thi Nguyet Pham, Tai Van Nugyen, Phuong Thi Nugyen, Ken Tanaka, Kinzo Matsumoto. Neuroprotective effects of Bacosides on ischemia-induced neuronal cell damage in organotypic hippocampal slice culture. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 180P-180P
Daishu Mizuki, Kinzo Matsumoto, Ken Tanaka, Hironori Fujiwara, Xoan T. Le, Yoshihiro Higuchi, Tsutomu Ishikawa. Antidepressant-like effects of Butea superba in mice exposed to chronic mild stress and its possible mechanism of action. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2014. 124. 129P-129P
Kinzo Matsumoto, Qi Zhao, Koichi Tsuneyama, Ken Tanaka, Feng Li, Takeshi Miyata. Chotosan ameliorates type 2 diabetes-induces cognitive deficits via improvement of central cholinergic and VEGF/PDGF systems in mice. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 186P-186P
Lectures and oral presentations (28)：
Characterization of the newly developed ginger cultivar as a novel resource for Kampo medicine
(International workshop on quality control of natural product 2013)
Trend of quality control of herbal medicines in Japan
(nternational workshop on quality control of natural product 2013)
RNA-Seq analysis of curcuminoid synthesis pathway of Curcumin longa
(The 2013 International Conference on AMT and BHI 2013)
玄米発酵による機能性成分の生成に関する研究
(日本生薬学会第60回年会 2013)
Asperoside B, a new iridoid trimer derivative from the roots of Dipsacus asper
(日本薬学会第133年会 2013)
