Yamaoka Yohsuke

Affiliation and department：

Research field (1)： Pharmaceuticals - chemistry and drug development

Research theme for competitive and other funds (8)：

2024 - 2027 Efficient Synthesis of Cyclobutanes by Multicomponent Reaction Using Ynolates and Its Application for Drug Discovery
2021 - 2024 新規発生法によるイノラートを用いた炭素四員環形成とその応用
2019 - 2022 Design, Synthesis and Evaluation of Biologically Active Molecules Based on Ring Strain
2018 - 2021 Divergent Synthesis of Nitrogen-Containing Heterocycles by Sequential Reactions and Its Application to Drug Discovery
2016 - 2019 Stereocontrolled synthesis of poly-substituted medium-sized cyclic compounds by electrocyclic ring opening reaction and the synthesis of biologically active molecules

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Papers (69)：

Mai Takagi, Ayana Nagatani, Kenichi Kawano, Ayami Hata, Azusa Yokoyama, Koichi Hayashida, Haruka Hoshi, Mao Sakurai, Tsuyoshi Oyama, Yusuke Kuroda, et al. Stable and Minimum Size Solubilization of Membrane Proteins with Cocktails of Phospholipid Analogues. ACS Applied Materials & Interfaces. 2024
Kazuma Kurokawa, Naoki Ogawa, Yusuke Kuroda, Yousuke Yamaoka, Hiroshi Takikawa, Kazunori Tsubaki, Kiyosei Takasu. Chromic properties of dibenzo[j,l]fluoranthenes exhibiting different resonance contributions. Organic & biomolecular chemistry. 2024
Eito Yoshioka, Yuuki Imoto, Yousuke Yamaoka, Tomoko Ikeda, Hiroki Takahashi, Ryousuke Tanaka, Naoki Hayashi, Hideto Miyabe. Intramolecular Cyclopropanation of Active Methylene Derivatives Based on FeCl2 or FeCl3-Promoted Radical-Polar Crossover Reactions. Chemistry - A European Journal. 2024
Yousuke Yamaoka, Hideto Miyabe. NHC-Catalyzed Reaction of Aldehydes for C(sp2)-O Bond Formation. Catalysts. 2024
Yousuke Yamaoka, Hidetaka Imahori, Motoki Namioka, Ryo Nishina, Yukiko Kobori, Motoki Ueda, Mitsuru Shindo, Kiyosei Takasu. Entry into Lithium Ynolates from α,α,α-Tribromomethyl Ketones: Synthesis of Cyclobutenes via the [2 + 2] Cycloaddition with α,β-Unsaturated Carbonyls. Organic Letters. 2024

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MISC (127)：

三和空知, 瀧川紘, 竹内莉奈, 小田島圭, 水沼諒, 山岡庸介, 潘東青, 加藤博章, 高須清誠. ABCトランスポーターとの共結晶形成を指向したローダミン誘導体の合成と評価. 次世代を担う有機化学シンポジウム講演要旨集. 2022. 20th
田渡司, 加藤律希, 山岡庸介, 高須清誠, 瀧川紘. Benzyne platform for intramolecular ene reaction, part 2: Application to expeditious synthesis of highly functionalized allenamides. 日本薬学会年会要旨集(Web). 2022. 142nd
瀧川紘, 加藤律希, 田渡司, 山岡庸介, 高須清誠. Benzyne platform for intramolecular ene reaction, part 1: Application to stereoselective arylation of allyl alcohols. 日本薬学会年会要旨集(Web). 2022. 142nd
三和空知, 水谷大地, 山岡庸介, 高須清誠, 瀧川紘. Synthesis and optical properties of helicene-xanthene hybrid dyes. 日本薬学会年会要旨集(Web). 2022. 142nd
山岡庸介, 梶原大悟, 瀧川紘, 高須清誠. Photoinduced domino reaction of ynamide leading to N-heterocycles. 日本薬学会年会要旨集(Web). 2022. 142nd

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Books (1)：

Methods and Applications of Cycloaddition Reactions in Organic Syntheses
Wiley-VCH 2013

Lectures and oral presentations (15)：

エン-イナミドを用いた含窒素複素環の合成法の開発と応用
(第44回反応と合成の進歩シンポジウム 2018)
ブレンステッド酸によるイナミドの分子内スピロ環化反応の開発
(第68回日本薬学会近畿支部総会・大会 2018)
イナミドを用いた新規スピロインドリン合成法の開発
(日本薬学会第138年会 2018)
ケテンシリルアセタールの触媒的(2+2)環化付加によるシクロブテンの合成
(日本プロセス化学会2017サマーシンポジウム 2017)
イナミドを用いた含窒素複素環合成
(イナミドを用いた含窒素複素環合成 2017)

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