2022 - 2025 Epigenetics for cancer metabolism regulation -elucidation of hemangiosarcoma pathogenesis and search for a novel therapeutic target -
2020 - 2022 Epigenetics of Hemangiosarcoma - The Roles of KDM2B and Hemangiosarcoma Mouse Model -
2020 - 2021 Generating mouse hemangiosarcoma model
2016 - 2020 Investigation of the mechanism of equine herpesvirus-1 latency using mice expressing a viral receptor
2018 - 2020 Unveiling the epigenetic mechanism of cellular differentiation in undifferentiated canine hemangiosarcoma cells
2016 - 2017 Regulation of abnormal endothelial cells - comparative pathology of hemangiosarcoma and tumor blood vessels -
2016 - 2017 Analysis of Notch signaling in canine hemangiosarcoma to search for novel treatment targets
2010 - 2015 Understanding the "genome adaptation" in fertilized embryo
2013 - 2015 Analysis of chromatin dynamics of mouse prenuclear zygote
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Papers (49):
Mayuko Maeda, Miou Abe, Keisuke Aoshima, Atsushi Kobayashi, Hideto Fukushi, Takashi Kimura. Identification of the Promoter Antisense Transcript Enhancing the Transcription of the Equine Herpesvirus-1 Immediate-Early Gene. Viruses. 2024. 16. 8
Mariko Miki, Ryo Daniel Obara, Kyohei Nishimura, Takao Shishido, Yoshinori Ikenaka, Ryoko Oka, Kenji Sato, Shouta M M Nakayama, Takashi Kimura, Atsushi Kobayashi, et al. FOUR-WEEK ORAL ADMINISTRATION OF BALOXAVIR MARBOXIL AS AN ANTI-INFLUENZA VIRUS DRUG SHOWS NO TOXICITY IN CHICKENS. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 2024. 55. 2. 313-321
N Nagata, K Aoshima, K Nakamura, M Takiguchi. Adrenocortical hypoperfusion detected by contrast-enhanced ultrasound in a dog with trilostane-induced hypoadrenocorticism. The Journal of small animal practice. 2023. 64. 11. 722-726
Yu Asari, Jumpei Yamazaki, Oo Thandar, Tamami Suzuki, Keisuke Aoshima, Kyosuke Takeuchi, Ryohei Kinoshita, Sangho Kim, Kenji Hosoya, Teita Ishizaki, et al. Diverse genome-wide DNA methylation alterations in canine hepatocellular tumours. Veterinary medicine and science. 2023
Atsushi Kobayashi, Tetsuya Hirata, Taishi Shimazaki, Yoshiko Munesue, Keisuke Aoshima, Takashi Kimura, Junko Nio-Kobayashi, Rie Hasebe, Atsuko Takeuchi, Yuichi Matsuura, et al. A point mutation in GPI-attachment signal peptide accelerates the development of prion disease. Acta neuropathologica. 2023. 145. 5. 637-650
鈴木玲海, 青島圭佑, 山崎淳平, 安井博宣, 平島一輝, 木村享史. Investigation of the roles of histone lactylation and glutamine metabolism in canine hemangiosarcoma. 日本癌学会学術総会抄録集(Web). 2023. 82nd